| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Friends with Benefits | $543,243 | - | 86 | - | $6,316 | $667,479 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Crazy, Stupid, Love. | $235,780 | -50.7% | 90 | +2 | $2,619 | $1,616,686 | 3 | Warner Bros. | false | false |
| 3 | - | Colombiana | $192,878 | - | 41 | - | $4,704 | $255,413 | 1 | Dutch FilmWorks (DFW) | true | false |
| 4 | 3 | Midnight in Paris | $153,728 | -35.7% | 55 | +14 | $2,795 | $511,554 | 2 | Paramount Pictures International | false | false |
| 5 | - | Shark Night | $146,527 | - | 51 | - | $2,873 | $185,471 | 1 | Entertainment One | true | false |
| 6 | 2 | The Smurfs | $140,744 | -53% | 160 | +3 | $879 | $8,156,948 | 8 | Sony Pictures Releasing | false | false |
| 7 | 4 | De president | $118,474 | -48% | 76 | -1 | $1,558 | $428,622 | 2 | A-Film Distribution | false | false |
| 8 | 5 | Rise of the Planet of the Apes | $92,785 | -42.8% | 80 | -18 | $1,159 | $2,872,990 | 6 | Warner Bros. | false | false |
| 9 | 7 | Harry Potter and the Deathly Hallows: Part 2 | $76,801 | -37% | 98 | -22 | $783 | $17,278,061 | 11 | Warner Bros. | false | false |
| 10 | - | Isabelle | $71,436 | - | 63 | - | $1,133 | $71,436 | 1 | A-Film Distribution | true | false |
| 11 | 6 | Final Destination 5 | $67,030 | -49.6% | 57 | -10 | $1,175 | $1,610,381 | 5 | Warner Bros. | false | false |
| 12 | 8 | Conan the Barbarian | $45,925 | -60.9% | 49 | -33 | $937 | $488,667 | 3 | Benelux Film Distributors | false | false |
| 13 | 10 | Mr. Popper's Penguins | $45,259 | -43.6% | 89 | - | $508 | $1,679,324 | 7 | Warner Bros. | false | false |
| 14 | 12 | Melancholia | $35,949 | -44.6% | 23 | - | $1,563 | $527,213 | 5 | Wild Bunch Distribution | false | false |
| 15 | 15 | The Devil's Double | $32,316 | -44.4% | 19 | -3 | $1,700 | $387,975 | 3 | A-Film Distribution | false | false |
| 16 | 9 | Horrible Bosses | $31,946 | -62.3% | 42 | -18 | $760 | $2,874,135 | 9 | Warner Bros. | false | false |
| 17 | 11 | Apollo 18 | $30,199 | -61.6% | 29 | -1 | $1,041 | $144,058 | 2 | Entertainment One | false | false |
| 18 | 14 | Flypaper | $25,392 | -57.5% | 18 | -3 | $1,410 | $378,762 | 4 | Independent Films | false | false |
| 19 | 16 | Cars 2 | $20,960 | -54.8% | 105 | -13 | $199 | $6,037,506 | 12 | Walt Disney Pictures | false | false |
| 20 | 13 | Cowboys & Aliens | $16,939 | -71.9% | 26 | -37 | $651 | $996,633 | 5 | Universal Pictures International (UPI) | false | false |
