| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Final Destination 5 | $34,249 | - | 9 | - | $3,805 | $34,249 | 1 | Warner Bros. | true | false |
| 2 | 2 | Rise of the Planet of the Apes | $25,867 | -34.8% | 6 | - | $4,311 | $80,666 | 2 | 20th Century Fox International | false | false |
| 3 | 1 | The Smurfs | $24,093 | -41.3% | 10 | -2 | $2,409 | $645,470 | 6 | Sony Pictures Releasing | false | false |
| 4 | - | Friends with Benefits | $21,341 | - | 5 | - | $4,268 | $29,434 | 1 | Sony Pictures Releasing | true | false |
| 5 | 3 | Crazy, Stupid, Love. | $10,699 | -42.9% | 7 | +1 | $1,528 | $67,364 | 3 | Warner Bros. | false | false |
| 6 | 4 | Horrible Bosses | $10,345 | -33.6% | 4 | -1 | $2,586 | $153,889 | 6 | Warner Bros. | false | false |
| 7 | - | Gnomeo & Juliet | $9,847 | - | 8 | - | $1,230 | $9,847 | 1 | N/A | true | false |
| 8 | 6 | Midnight in Paris | $9,401 | -28.2% | 6 | - | $1,566 | $343,813 | 9 | N/A | false | false |
| 9 | 7 | La Rodata | $8,638 | -9.2% | 5 | -2 | $1,727 | $168,567 | 7 | N/A | false | false |
| 10 | 5 | Green Lantern | $6,007 | -60.8% | 6 | - | $1,001 | $107,078 | 4 | Warner Bros. | false | false |
| 11 | 8 | Insidious | $4,091 | -50% | 3 | - | $1,363 | $40,020 | 4 | N/A | false | false |
| 12 | 9 | Larry Crowne | $3,822 | -45% | 4 | -2 | $955 | $65,417 | 4 | N/A | false | false |
| 13 | 10 | Rabbit Hole | $3,107 | -44.5% | 3 | - | $1,035 | $11,762 | 2 | N/A | false | false |
| 14 | - | Of Gods and Men | $2,834 | - | 1 | - | $2,834 | $2,834 | 1 | N/A | true | false |
| 15 | 13 | Blue Valentine | $2,535 | -16% | 2 | - | $1,267 | $6,459 | 2 | N/A | false | false |
| 16 | 11 | Zookeeper | $2,477 | -53.7% | 4 | -2 | $619 | $268,200 | 10 | Sony Pictures Releasing | false | false |
| 17 | 12 | Cowboys & Aliens | $1,372 | -70.2% | 4 | -1 | $343 | $21,628 | 3 | Paramount Pictures International | false | false |
| 18 | 14 | Incendies | $1,367 | -30% | 2 | - | $683 | $18,635 | 5 | N/A | false | false |
| 19 | 16 | The Human Resources Manager | $922 | -28.6% | 1 | - | $922 | $4,902 | 3 | N/A | false | false |
| 20 | 18 | The Lincoln Lawyer | $495 | -48.2% | 1 | - | $495 | $48,602 | 8 | N/A | false | false |
| 21 | 15 | Harry Potter and the Deathly Hallows: Part 2 | $400 | -72.7% | 1 | - | $400 | $558,523 | 9 | Warner Bros. | false | false |
| 22 | 20 | Mr. Popper's Penguins | $394 | -17.2% | 2 | - | $197 | $200,390 | 11 | 20th Century Fox International | false | false |
| 23 | 24 | Kung Fu Panda 2 | $39 | -70% | 1 | - | $39 | $798,202 | 14 | Paramount Pictures International | false | false |
