| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Smurfs | $1,644,029 | +27.1% | 178 | +12 | $9,236 | $4,861,836 | 2 | Sony Pictures Releasing | false | false |
| 2 | 2 | Harry Potter and the Deathly Hallows: Part 2 | $916,208 | -14.8% | 192 | -8 | $4,771 | $15,778,517 | 5 | Warner Bros. | false | false |
| 3 | - | Super 8 | $606,160 | - | 84 | - | $7,216 | $663,753 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | - | Mr. Popper's Penguins | $454,976 | - | 95 | - | $4,789 | $553,628 | 1 | Warner Bros. | true | false |
| 5 | 3 | Horrible Bosses | $335,312 | -15% | 86 | - | $3,898 | $1,725,207 | 3 | Warner Bros. | false | false |
| 6 | 5 | Cars 2 | $313,562 | +14.4% | 162 | -1 | $1,935 | $5,747,939 | 6 | Walt Disney Pictures | false | false |
| 7 | 6 | Captain America: The First Avenger | $175,548 | -35.3% | 74 | -1 | $2,372 | $1,346,514 | 3 | Universal Pictures International (UPI) | false | false |
| 8 | 4 | Green Lantern | $165,541 | -51.7% | 84 | - | $1,970 | $676,925 | 2 | Warner Bros. | false | false |
| 9 | 7 | Honey 2 | $136,860 | -22% | 30 | +1 | $4,562 | $442,448 | 2 | Universal Pictures International (UPI) | false | false |
| 10 | 8 | Monte Carlo | $124,335 | -10.3% | 47 | - | $2,645 | $749,123 | 3 | Warner Bros. | false | false |
| 11 | 9 | Bridesmaids | $116,912 | -6% | 59 | -4 | $1,981 | $2,345,021 | 6 | Universal Pictures International (UPI) | false | false |
| 12 | 14 | Kung Fu Panda 2 | $102,587 | +27.9% | 94 | -15 | $1,091 | $5,242,657 | 9 | Universal Pictures International (UPI) | false | false |
| 13 | 10 | Larry Crowne | $90,514 | -13.2% | 45 | +1 | $2,011 | $273,892 | 2 | Entertainment One | false | false |
| 14 | - | A Separation | $79,670 | - | 12 | - | $6,639 | $81,067 | 1 | Cinéart | true | false |
| 15 | 11 | Transformers: Dark of the Moon | $62,061 | -39.9% | 27 | -16 | $2,298 | $5,567,580 | 7 | Universal Pictures International (UPI) | false | false |
| 16 | 13 | Bad Teacher | $53,013 | -40.2% | 49 | -17 | $1,081 | $4,291,217 | 8 | Sony Pictures Releasing | false | false |
| 17 | 12 | Zookeeper | $49,592 | -48% | 48 | -8 | $1,033 | $924,898 | 4 | Sony Pictures Releasing | false | false |
| 18 | 17 | Pina | $44,953 | +17.6% | 14 | - | $3,210 | $595,694 | 6 | Cinéart | false | false |
| 19 | 19 | Penny's Shadow | $40,233 | +10.6% | 61 | -22 | $659 | $1,696,199 | 10 | Independent Films | false | false |
| 20 | 20 | The Tree of Life | $40,233 | +13.1% | 16 | - | $2,514 | $1,125,819 | 11 | Independent Films | false | false |
