| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Crazy, Stupid, Love. | $52,302 | - | 5 | - | $10,460 | $52,302 | 1 | Warner Bros. | true | false |
| 2 | 1 | Harry Potter and the Deathly Hallows: Part 2 | $45,679 | -37% | 11 | - | $4,152 | $422,120 | 3 | Warner Bros. | false | false |
| 3 | 2 | Zookeeper | $35,693 | -29.4% | 9 | - | $3,965 | $117,321 | 2 | Sony Pictures Releasing | false | false |
| 4 | 6 | Horrible Bosses | $24,126 | -10.3% | 5 | +1 | $4,825 | $193,536 | 4 | Warner Bros. | false | false |
| 5 | 4 | Transformers: Dark of the Moon | $18,402 | -42.7% | 6 | -4 | $3,067 | $513,796 | 5 | United International Pictures | false | false |
| 6 | 5 | Mr. Popper's Penguins | $17,820 | -40.9% | 7 | -2 | $2,545 | $226,080 | 4 | 20th Century Fox International | false | false |
| 7 | 3 | Bridesmaids | $16,816 | -48% | 8 | -1 | $2,102 | $70,837 | 2 | United International Pictures | false | false |
| 8 | - | The Extraordinary Adventures of Adèle Blanc-Sec | $12,110 | - | 5 | - | $2,422 | $12,110 | 1 | N/A | true | false |
| 9 | - | The True Story of Puss'N Boots | $11,169 | - | 7 | - | $1,595 | $11,169 | 1 | N/A | true | false |
| 10 | - | Sami Oxide El Carbone | $5,995 | - | 2 | - | $2,997 | $58,519 | 4 | N/A | false | false |
| 11 | 9 | Bad Teacher | $4,235 | -47.9% | 1 | -2 | $4,235 | $233,496 | 6 | Sony Pictures Releasing | false | false |
| 12 | - | Black Death | $4,110 | - | 4 | - | $1,027 | $4,110 | 1 | N/A | true | false |
| 13 | 8 | The Ward | $2,544 | -73.8% | 5 | - | $508 | $19,260 | 2 | Italian International Film | false | false |
| 14 | 10 | Monte Carlo | $2,297 | -60.2% | 2 | -2 | $1,148 | $129,832 | 5 | 20th Century Fox International | false | false |
| 15 | 12 | Winnie the Pooh | $2,200 | -28.9% | 3 | -2 | $733 | $19,358 | 3 | Walt Disney Pictures | false | false |
| 16 | 11 | Cars 2 | $1,829 | -65.2% | 2 | - | $914 | $204,209 | 6 | Walt Disney Pictures | false | false |
| 17 | 7 | The Romantics | $1,825 | -82.4% | 3 | -2 | $608 | $18,681 | 2 | N/A | false | false |
| 18 | 13 | Fast Five | $1,340 | -23% | 1 | - | $1,340 | $519,841 | 13 | United International Pictures | false | false |
| 19 | 17 | Larry Crowne | $964 | +9.4% | 1 | - | $964 | $95,447 | 5 | Jaguar Film International Distribution | false | false |
| 20 | 16 | Sorry Mom | $748 | -26% | 2 | - | $374 | $105,508 | 8 | N/A | false | false |
| 21 | 19 | Pirates of the Caribbean: On Stranger Tides | $693 | +18.3% | 1 | - | $693 | $474,558 | 11 | Walt Disney Pictures | false | false |
| 22 | 21 | Jane Eyre | $317 | -13.9% | 1 | - | $317 | $20,646 | 9 | Italian International Film | false | false |
| 23 | 20 | The Father and the Foreigner | $245 | -35.9% | 1 | - | $245 | $1,364 | 3 | N/A | false | false |
| 24 | 15 | Kung Fu Panda 2 | $184 | -88.7% | 1 | - | $184 | $308,245 | 9 | United International Pictures | false | false |
| 25 | 18 | Honey 2 | $77 | -89.7% | 1 | -1 | $77 | $39,454 | 4 | United International Pictures | false | false |
| 26 | - | Eleanor's Secret 2010 Re-release | $26 | - | 1 | - | $26 | $747 | 10 | N/A | false | false |
