| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: On Stranger Tides | $44,502 | -38.2% | 12 | - | $3,708 | $181,773 | 2 | Walt Disney Pictures | false | false |
| 2 | - | The Hangover Part II | $38,823 | - | 7 | - | $5,546 | $55,965 | 1 | Warner Bros. | true | false |
| 3 | 2 | Rio | $7,463 | +23.2% | 14 | - | $533 | $315,491 | 7 | 20th Century Fox International | false | false |
| 4 | 3 | The White Lions | $2,280 | -57.3% | 10 | - | $228 | $119,408 | 5 | N/A | false | false |
| 5 | - | The Lincoln Lawyer | $1,721 | - | 5 | - | $344 | $1,721 | 1 | N/A | true | false |
| 6 | - | The Ages of Love | $1,510 | - | 2 | - | $755 | $6,575 | 1 | N/A | true | false |
| 7 | 5 | Just Go with It | $1,172 | -55.4% | 7 | -1 | $167 | $79,652 | 8 | Sony Pictures Releasing | false | false |
| 8 | 6 | Thor | $1,002 | -58.6% | 5 | - | $200 | $70,141 | 5 | United International Pictures | false | false |
| 9 | - | Something Borrowed | $994 | - | 3 | - | $331 | $12,329 | 3 | N/A | false | false |
| 10 | 9 | Water for Elephants | $982 | -18.4% | 5 | - | $196 | $27,957 | 6 | 20th Century Fox International | false | false |
| 11 | 4 | Red Riding Hood | $892 | -67.3% | 7 | - | $127 | $44,075 | 5 | Warner Bros. | false | false |
| 12 | 7 | Fast Five | $882 | -55.6% | 4 | - | $220 | $41,098 | 4 | United International Pictures | false | false |
| 13 | - | Love & Other Drugs | $718 | - | 4 | - | $179 | $21,564 | 11 | 20th Century Fox International | false | false |
| 14 | 8 | Unknown | $607 | -59.9% | 7 | - | $86 | $45,417 | 6 | Warner Bros. | false | false |
| 15 | 12 | The Rite | $412 | +24.1% | 7 | - | $58 | $46,496 | 7 | Warner Bros. | false | false |
| 16 | 10 | Hereafter | $364 | -48.6% | 4 | - | $91 | $28,795 | 9 | Warner Bros. | false | false |
| 17 | 11 | Source Code | $214 | -63.5% | 4 | - | $53 | $24,963 | 8 | N/A | false | false |
| 18 | 14 | Hop | $191 | +21.7% | 5 | - | $38 | $16,921 | 9 | Walt Disney Pictures | false | false |
| 19 | 18 | Battle Los Angeles | $150 | +66.7% | 4 | +2 | $37 | $27,958 | 11 | Sony Pictures Releasing | false | false |
| 20 | 15 | Rango | $143 | -4% | 5 | - | $28 | $52,411 | 11 | United International Pictures | false | false |
| 21 | 20 | Hall Pass | $105 | +94.4% | 7 | - | $15 | $33,345 | 11 | Warner Bros. | false | false |
| 22 | 16 | Black Swan | $87 | -17.1% | 5 | - | $17 | $103,749 | 12 | 20th Century Fox International | false | false |
| 23 | 13 | Limitless | $71 | -73.7% | 4 | - | $17 | $61,780 | 10 | N/A | false | false |
