| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Pirates of the Caribbean: On Stranger Tides | $72,047 | - | 12 | - | $6,003 | $93,172 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Rio | $6,060 | -53.3% | 14 | - | $432 | $303,348 | 6 | 20th Century Fox International | false | false |
| 3 | 4 | The White Lions | $5,339 | -19.3% | 10 | - | $533 | $113,969 | 4 | N/A | false | false |
| 4 | 5 | Red Riding Hood | $2,730 | -37% | 7 | - | $390 | $41,652 | 4 | Warner Bros. | false | false |
| 5 | 7 | Just Go with It | $2,626 | +23.6% | 8 | - | $328 | $77,379 | 7 | Sony Pictures Releasing | false | false |
| 6 | 2 | Thor | $2,421 | -65.9% | 5 | - | $484 | $66,400 | 4 | United International Pictures | false | false |
| 7 | 3 | Fast Five | $1,988 | -70.5% | 4 | - | $497 | $37,048 | 3 | United International Pictures | false | false |
| 8 | 6 | Unknown | $1,514 | -29.6% | 7 | - | $216 | $43,856 | 5 | Warner Bros. | false | false |
| 9 | 8 | Water for Elephants | $1,203 | -12.3% | 5 | - | $240 | $25,875 | 5 | 20th Century Fox International | false | false |
| 10 | 25 | Hereafter | $708 | +5,346.2% | 4 | - | $177 | $27,925 | 8 | Warner Bros. | false | false |
| 11 | 9 | Source Code | $586 | -47.4% | 4 | - | $146 | $24,056 | 7 | N/A | false | false |
| 12 | 10 | The Rite | $332 | -61.1% | 7 | - | $47 | $45,828 | 6 | Warner Bros. | false | false |
| 13 | 13 | Limitless | $270 | -33% | 4 | - | $67 | $61,512 | 9 | N/A | false | false |
| 14 | 15 | Hop | $157 | -43.5% | 5 | - | $31 | $16,532 | 8 | Walt Disney Pictures | false | false |
| 15 | 12 | Rango | $149 | -70.6% | 5 | - | $29 | $52,128 | 10 | United International Pictures | false | false |
| 16 | 21 | Black Swan | $105 | +5% | 5 | - | $21 | $103,472 | 11 | 20th Century Fox International | false | false |
| 17 | 14 | Potiche | $97 | -73.8% | 1 | - | $97 | $18,774 | 5 | N/A | false | false |
| 18 | 18 | Battle Los Angeles | $90 | -52.6% | 2 | - | $45 | $27,628 | 10 | Sony Pictures Releasing | false | false |
| 19 | 17 | How Do You Know | $90 | -58.7% | 1 | -3 | $90 | $27,087 | 13 | Sony Pictures Releasing | false | false |
| 20 | 23 | Hall Pass | $54 | -37.2% | 7 | - | $7 | $33,132 | 10 | Warner Bros. | false | false |
| 21 | 24 | Sucker Punch | $37 | -43.1% | 7 | - | $5 | $15,446 | 9 | Warner Bros. | false | false |
| 22 | 19 | Drive Angry | $16 | -90.8% | 8 | - | $2 | $41,251 | 12 | Warner Bros. | false | false |
