| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Rio | $12,983 | -34.9% | 14 | - | $927 | $291,255 | 5 | 20th Century Fox International | false | false |
| 2 | 4 | Thor | $7,092 | -34.3% | 5 | - | $1,418 | $58,749 | 3 | United International Pictures | false | false |
| 3 | 3 | Fast Five | $6,733 | -43.2% | 4 | - | $1,683 | $29,912 | 2 | United International Pictures | false | false |
| 4 | 2 | The White Lions | $6,614 | -49.5% | 10 | - | $661 | $102,693 | 3 | N/A | false | false |
| 5 | 5 | Red Riding Hood | $4,336 | -29.6% | 7 | - | $619 | $35,972 | 3 | Warner Bros. | false | false |
| 6 | 6 | Unknown | $2,150 | -50.3% | 7 | - | $307 | $39,776 | 4 | Warner Bros. | false | false |
| 7 | 7 | Just Go with It | $2,125 | -42.6% | 8 | - | $265 | $73,175 | 6 | Sony Pictures Releasing | false | false |
| 8 | 8 | Water for Elephants | $1,372 | -42.4% | 5 | - | $274 | $22,476 | 4 | 20th Century Fox International | false | false |
| 9 | 17 | Source Code | $1,115 | +218.6% | 4 | - | $278 | $22,437 | 6 | N/A | false | false |
| 10 | 10 | The Rite | $854 | -43.5% | 7 | - | $122 | $44,735 | 5 | Warner Bros. | false | false |
| 11 | 19 | Montevideo: Taste of a Dream | $521 | +98.9% | 19 | - | $27 | $2,192,931 | 21 | N/A | false | false |
| 12 | 16 | Rango | $506 | +34.2% | 5 | - | $101 | $51,892 | 9 | United International Pictures | false | false |
| 13 | 11 | Limitless | $403 | -46.7% | 4 | - | $100 | $60,733 | 8 | N/A | false | false |
| 14 | 14 | Potiche | $370 | -35.4% | 1 | - | $370 | $18,568 | 4 | N/A | false | false |
| 15 | 13 | Hop | $278 | -53.3% | 5 | - | $55 | $16,349 | 7 | Walt Disney Pictures | false | false |
| 16 | 12 | The King's Speech | $266 | -62.7% | 4 | - | $66 | $86,214 | 11 | N/A | false | false |
| 17 | 27 | How Do You Know | $218 | +113.7% | 4 | +1 | $54 | $26,917 | 12 | Sony Pictures Releasing | false | false |
| 18 | 22 | Battle Los Angeles | $190 | +38.7% | 2 | - | $95 | $27,414 | 9 | Sony Pictures Releasing | false | false |
| 19 | 20 | Drive Angry | $173 | -30.2% | 8 | - | $21 | $41,064 | 11 | Warner Bros. | false | false |
| 20 | 25 | Love & Other Drugs | $121 | +10% | 4 | - | $30 | $20,364 | 9 | 20th Century Fox International | false | false |
| 21 | 15 | Black Swan | $100 | -80% | 5 | - | $20 | $103,184 | 10 | 20th Century Fox International | false | false |
| 22 | 18 | He Ain't Like That | $90 | -67.2% | 9 | - | $10 | $62,358 | 9 | N/A | false | false |
| 23 | 21 | Hall Pass | $86 | -37.7% | 7 | - | $12 | $33,018 | 9 | Warner Bros. | false | false |
| 24 | 26 | Sucker Punch | $65 | -36.3% | 7 | - | $9 | $15,253 | 8 | Warner Bros. | false | false |
| 25 | 30 | Hereafter | $13 | -85.6% | 4 | - | $3 | $27,000 | 7 | Warner Bros. | false | false |
