| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Escort in Love | $2,139,775 | -19.8% | 485 | +13 | $4,411 | $7,499,667 | 2 | 01 Distribution | false | false |
| 2 | - | No Strings Attached | $974,215 | - | 258 | - | $3,776 | $975,872 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 2 | Amici miei - Come tutto ebbe inizio | $789,015 | -51.4% | 373 | -100 | $2,115 | $4,242,084 | 2 | Filmauro | false | false |
| 4 | - | Sucker Punch | $705,944 | - | 279 | - | $2,530 | $705,944 | 1 | Warner Bros. | true | false |
| 5 | 3 | Rango | $634,999 | -47.6% | 316 | -81 | $2,009 | $6,596,443 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | Dylan Dog: Dead of Night | $542,778 | -51.6% | 238 | -12 | $2,280 | $2,918,734 | 2 | Moviemax | false | false |
| 7 | 6 | Gnomeo & Juliet | $412,124 | -42.1% | 275 | -2 | $1,498 | $1,926,091 | 2 | Walt Disney Pictures | false | false |
| 8 | 5 | The Rite | $395,841 | -54.1% | 160 | -117 | $2,474 | $4,657,234 | 3 | Warner Bros. | false | false |
| 9 | - | Frozen | $366,081 | - | 102 | - | $3,589 | $366,081 | 1 | N/A | true | false |
| 10 | - | The Last Fashion Show | $364,868 | - | 325 | - | $1,122 | $364,958 | 1 | Medusa Distribuzione | true | false |
| 11 | 8 | The King's Speech | $308,506 | -25.6% | 114 | -26 | $2,706 | $11,451,350 | 9 | Eagle Pictures | false | false |
| 12 | 7 | StreetDance 2 | $285,815 | -57.5% | 160 | -67 | $1,786 | $1,643,751 | 2 | Eagle Pictures | false | false |
| 13 | - | Silvio Forever | $256,979 | - | 104 | - | $2,470 | $256,979 | 1 | Lucky Red | true | false |
| 14 | - | Never Let Me Go | $240,037 | - | 99 | - | $2,424 | $240,037 | 1 | 20th Century Fox International | true | false |
| 15 | 10 | The Kids Are All Right | $186,567 | -42% | 81 | -40 | $2,303 | $1,560,490 | 3 | Lucky Red | false | false |
| 16 | 9 | Black Swan | $162,786 | -51.3% | 86 | -67 | $1,892 | $8,130,352 | 6 | 20th Century Fox International | false | false |
| 17 | 11 | La vita facile | $86,962 | -72.1% | 56 | -118 | $1,552 | $3,629,129 | 4 | Medusa Distribuzione | false | false |
| 18 | 14 | Sorelle mai | $79,221 | -25.5% | 37 | -4 | $2,141 | $272,859 | 2 | Teodora Film | false | false |
| 19 | 12 | The Fighter | $78,100 | -64.7% | 39 | -66 | $2,002 | $3,044,691 | 4 | Eagle Pictures | false | false |
| 20 | 15 | The Jewel | $70,509 | -30.4% | 26 | -17 | $2,711 | $1,205,614 | 4 | BIM Distribuzione | false | false |
| 21 | 19 | True Grit | $22,057 | -47.5% | 12 | -9 | $1,838 | $4,080,682 | 6 | Universal Pictures International (UPI) | false | false |
| 22 | - | Space Dogs | $20,729 | - | 47 | - | $441 | $20,729 | 1 | One Movie | true | false |
| 23 | 30 | On Tour | $17,823 | +23.3% | 11 | +1 | $1,620 | $47,103 | 2 | N/A | false | false |
| 24 | 24 | Winter's Bone | $17,783 | -36.2% | 9 | -5 | $1,975 | $481,005 | 6 | Bolero Film | false | false |
| 25 | 13 | The Ages of Love | $17,246 | -85.5% | 15 | -78 | $1,149 | $9,284,301 | 5 | Filmauro | false | false |
| 26 | 26 | Another Year | $14,570 | -34.6% | 4 | -4 | $3,642 | $1,112,497 | 8 | BIM Distribuzione | false | false |
| 27 | 25 | Beyond | $12,452 | -49.8% | 11 | -2 | $1,132 | $59,549 | 2 | Sacher Distribuzione | false | false |
| 28 | 32 | Barney's Version | $10,630 | -5.4% | 4 | -2 | $2,657 | $3,591,952 | 11 | Medusa Distribuzione | false | false |
| 29 | 29 | Le stelle inquiete | $9,107 | -41.4% | 4 | -1 | $2,276 | $64,635 | 3 | Bolero Film | false | false |
| 30 | 16 | All at Sea | $7,965 | -84.7% | 6 | -73 | $1,327 | $626,012 | 3 | 01 Distribution | false | false |
| 31 | 17 | Piranha 3D | $7,838 | -83.1% | 7 | -27 | $1,119 | $1,999,598 | 4 | BIM Distribuzione | false | false |
| 32 | 22 | 6 Souls | $6,561 | -78% | 3 | -4 | $2,187 | $672,570 | 5 | Moviemax | false | false |
| 33 | 31 | The Return of Don Camillo | $6,556 | -45.8% | 2 | -1 | $3,278 | $127,840 | 3 | N/A | false | false |
| 34 | 20 | The Immature | $6,432 | -78.7% | 4 | -10 | $1,608 | $21,251,294 | 10 | Medusa Distribuzione | false | false |
| 35 | 23 | Women Vs Men | $6,218 | -78.2% | 6 | -12 | $1,036 | $16,301,309 | 8 | Medusa Distribuzione | false | false |
| 36 | 42 | The Salt of Life | $5,939 | +47% | 3 | +1 | $1,979 | $1,179,250 | 7 | 01 Distribution | false | false |
| 37 | 28 | Hard Times | $5,798 | -68.1% | 8 | -19 | $724 | $148,498 | 3 | N/A | false | false |
| 38 | 47 | We Believed | $5,607 | +194% | 7 | +2 | $801 | $2,049,532 | 20 | 01 Distribution | false | false |
| 39 | - | Qualunquemente | $5,569 | - | 2 | - | $2,784 | $22,275,172 | 10 | 01 Distribution | false | false |
| 40 | - | Made in Dagenham | $5,175 | - | 3 | - | $1,725 | $1,265,114 | 17 | Lucky Red | false | false |
| 41 | - | Amici ahrarara | $4,900 | - | 2 | - | $2,450 | $2,430,275 | 524 | Filmauro | false | false |
| 42 | 37 | 127 Hours | $4,873 | -3.4% | 4 | -2 | $1,218 | $893,172 | 5 | 20th Century Fox International | false | false |
| 43 | - | Cradle 2 the Grave | $4,574 | - | 1 | - | $4,574 | $246,828 | 408 | Warner Bros. | false | false |
| 44 | 34 | In a Better World | $4,501 | -34.7% | 2 | -1 | $2,250 | $716,760 | 16 | Teodora Film | false | false |
| 45 | 45 | Biutiful | $4,195 | +43.1% | 4 | +1 | $1,048 | $442,570 | 8 | Universal Pictures International (UPI) | false | false |
| 46 | 35 | Gulliver's Travels | $4,185 | -37.3% | 5 | -6 | $837 | $4,863,940 | 8 | 20th Century Fox International | false | false |
| 47 | 36 | Gangor | $3,933 | -27.9% | 4 | -1 | $983 | $51,032 | 3 | N/A | false | false |
| 48 | - | Street Fighter | $3,444 | - | 1 | - | $3,444 | $2,794,549 | - | Sony Pictures Releasing | - | false |
| 49 | 18 | Unknown | $3,207 | -93% | 3 | -21 | $1,069 | $2,266,824 | 5 | Warner Bros. | false | false |
| 50 | 27 | Una cella in due | $2,751 | -86.3% | 3 | -4 | $917 | $353,508 | 4 | N/A | false | false |
