| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Big Mommas: Like Father, Like Son | $275,875 | - | 62 | - | $4,449 | $275,875 | 1 | NuMetro Distribution | true | false |
| 2 | 1 | Tangled | $218,728 | -17.4% | 76 | -7 | $2,878 | $2,277,561 | 5 | Ster-Kinekor Pictures | false | false |
| 3 | 3 | The King's Speech | $102,202 | -9.1% | 25 | - | $4,088 | $481,012 | 3 | Ster-Kinekor Pictures | false | false |
| 4 | 2 | How Do You Know | $84,800 | -35.9% | 44 | - | $1,927 | $268,503 | 2 | Ster-Kinekor Pictures | false | false |
| 5 | 8 | Saw 3D | $61,648 | -2.1% | 28 | - | $2,201 | $153,561 | 2 | Ster-Kinekor Pictures | false | false |
| 6 | - | The Fighter | $57,253 | - | 40 | - | $1,431 | $57,253 | 1 | Ster-Kinekor Pictures | true | false |
| 7 | 6 | The Tourist | $57,126 | -24.3% | 59 | -10 | $968 | $2,058,817 | 8 | Ster-Kinekor Pictures | false | false |
| 8 | 4 | The Green Hornet | $56,992 | -32.5% | 54 | -18 | $1,055 | $632,795 | 4 | Ster-Kinekor Pictures | false | false |
| 9 | 7 | Black Swan | $56,104 | -14.4% | 25 | - | $2,244 | $455,471 | 4 | NuMetro Distribution | false | false |
| 10 | 5 | Morning Glory | $53,223 | -30.1% | 60 | -1 | $887 | $339,202 | 3 | United International Pictures | false | false |
| 11 | 9 | Love & Other Drugs | $32,852 | -27.9% | 35 | -1 | $938 | $504,923 | 5 | NuMetro Distribution | false | false |
| 12 | 11 | The Next Three Days | $27,728 | -13.7% | 44 | - | $630 | $585,272 | 6 | NuMetro Distribution | false | false |
| 13 | 12 | True Grit | $23,609 | -24.2% | 12 | - | $1,967 | $71,619 | 2 | United International Pictures | false | false |
| 14 | 10 | 127 Hours | $22,750 | -30.3% | 18 | - | $1,263 | $71,453 | 2 | NuMetro Distribution | false | false |
| 15 | 14 | Gulliver's Travels | $17,362 | <0.1% | 26 | +4 | $667 | $956,551 | 8 | NuMetro Distribution | false | false |
| 16 | 13 | Burlesque | $13,259 | -40.4% | 20 | -6 | $662 | $554,028 | 6 | Ster-Kinekor Pictures | false | false |
| 17 | 17 | The Warrior's Way | $7,844 | -50.9% | 10 | -10 | $784 | $68,143 | 3 | NuMetro Distribution | false | false |
| 18 | - | Of Gods and Men | $7,389 | - | 8 | - | $923 | $7,389 | 1 | United International Pictures | true | false |
| 19 | 15 | Little Fockers | $7,159 | -57.5% | 12 | +3 | $596 | $1,956,834 | 10 | United International Pictures | false | false |
| 20 | - | The Concert | $6,435 | - | 6 | - | $1,072 | $206,551 | 8 | United International Pictures | false | false |
| 21 | 16 | Fair Game | $5,858 | -64% | 14 | -8 | $418 | $142,074 | 4 | NuMetro Distribution | false | false |
| 22 | 21 | Made in Dagenham | $2,318 | +6.5% | 3 | -2 | $772 | $111,748 | 6 | United International Pictures | false | false |
| 23 | 20 | Splice 2010 Re-release | $1,089 | -72% | 4 | - | $272 | $69,649 | 5 | United International Pictures | false | false |
