| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Harry Potter and the Deathly Hallows: Part 1 | $466,215 | -38.3% | 20 | - | $23,310 | $1,954,443 | 2 | Warner Bros. | false | false |
| 2 | - | The Next Three Days | $160,490 | - | 18 | - | $8,916 | $210,058 | 1 | N/A | true | false |
| 3 | - | Megamind | $51,943 | - | 18 | - | $2,885 | $64,488 | - | United International Pictures | - | false |
| 4 | 2 | Unstoppable | $41,716 | -49.1% | 15 | -2 | $2,781 | $819,966 | 3 | 20th Century Fox International | false | false |
| 5 | 4 | Confessions | $41,659 | -31.2% | 7 | - | $5,951 | $574,778 | 5 | N/A | false | false |
| 6 | - | Love Life | $39,404 | - | 6 | - | $6,567 | $54,791 | 1 | N/A | true | false |
| 7 | 3 | Skyline | $20,092 | -74.7% | 15 | -3 | $1,339 | $711,597 | 3 | N/A | false | false |
| 8 | - | Fair Game | $16,653 | - | 14 | - | $1,189 | $22,060 | 1 | Long Shong Entertainment Multimedia Company | true | false |
| 9 | - | Bayside Shakedown 3: Set the Guys Loose | $13,986 | - | 8 | - | $1,748 | $17,811 | 1 | N/A | true | false |
| 10 | 6 | Villain | $8,351 | -43.4% | 3 | - | $2,783 | $41,967 | 2 | N/A | false | false |
| 11 | 5 | The Social Network | $5,736 | -83.1% | 7 | -16 | $819 | $507,089 | 4 | Sony Pictures Releasing | false | false |
| 12 | - | Uncle Boonmee Who Can Recall His Past Lives | $3,714 | - | 3 | - | $1,238 | $5,173 | 1 | N/A | true | false |
| 13 | 7 | Saw 3D | $3,220 | -76% | 2 | -5 | $1,610 | $695,862 | 5 | N/A | false | false |
| 14 | 10 | Room in Rome | $2,412 | -34.5% | 2 | - | $1,206 | $12,439 | 2 | N/A | false | false |
| 15 | 12 | Howl | $943 | -49% | 1 | -1 | $943 | $6,444 | 2 | N/A | false | false |
| 16 | 13 | Nowhere Boy | $653 | -63.6% | 1 | -1 | $653 | $10,450 | 3 | N/A | false | false |
| 17 | - | The Servant | $474 | - | 1 | - | $474 | $825 | 1 | N/A | true | false |
| 18 | 17 | All About Love | $465 | -33.6% | 1 | -1 | $465 | $10,385 | 3 | N/A | false | false |
| 19 | 15 | Letters to God | $220 | -76.7% | 1 | -1 | $220 | $22,362 | 4 | N/A | false | false |
| 20 | 14 | RED | $129 | -90.9% | 1 | -2 | $129 | $986,414 | 7 | N/A | false | false |
