| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Deathly Hallows: Part 1 | $3,023,307 | - | 188 | - | $16,081 | $3,054,609 | 1 | Warner Bros. | true | false |
| 2 | 2 | Unstoppable | $261,375 | -55.3% | 50 | - | $5,227 | $894,302 | 2 | 20th Century Fox International | false | false |
| 3 | 3 | Zot van A. | $226,610 | -60.9% | 36 | - | $6,294 | $3,306,485 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 4 | 1 | Despicable Me | $204,594 | -72.3% | 114 | -9 | $1,794 | $3,563,054 | 4 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Due Date | $163,378 | -60% | 48 | - | $3,403 | $1,114,066 | 3 | Warner Bros. | false | false |
| 6 | 5 | Potiche | $148,081 | -48% | 28 | +1 | $5,288 | $517,539 | 2 | Cinéart | false | false |
| 7 | - | The Joneses | $127,396 | - | 21 | - | $6,066 | $165,971 | 1 | Benelux Film Distributors | true | false |
| 8 | 6 | The Social Network | $104,234 | -57.5% | 41 | - | $2,542 | $1,565,527 | 4 | Sony Pictures Releasing | false | false |
| 9 | 7 | Little White Lies | $98,412 | -56.5% | 24 | - | $4,100 | $1,277,525 | 5 | Cinéart | false | false |
| 10 | 8 | Arthur 3: The War of the Two Worlds | $64,616 | -67.6% | 56 | - | $1,153 | $1,226,028 | 5 | Belga Films | false | false |
| 11 | 14 | Saint | $60,837 | -44.2% | 9 | - | $6,759 | $179,382 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 12 | 10 | Paranormal Activity 2 | $52,842 | -70.8% | 24 | -1 | $2,201 | $1,389,289 | 5 | Universal Pictures International (UPI) | false | false |
| 13 | 11 | Sinterklaas en het pakjesmysterie | $49,438 | -70.8% | 23 | +1 | $2,149 | $383,226 | 3 | N/A | false | false |
| 14 | 17 | Fair Game | $39,200 | -54.6% | 16 | - | $2,450 | $164,511 | 2 | Belga Films | false | false |
| 15 | 13 | The American | $38,609 | -69.1% | 35 | - | $1,103 | $802,369 | 4 | Benelux Film Distributors | false | false |
| 16 | 9 | Legend of the Guardians: The Owls of Ga'Hoole | $36,850 | -81.2% | 59 | -12 | $624 | $1,483,953 | 6 | Warner Bros. | false | false |
| 17 | 12 | Jackass 3D | $25,010 | -80.9% | 13 | -6 | $1,923 | $406,948 | 3 | Universal Pictures International (UPI) | false | false |
| 18 | 18 | A Turtle's Tale: Sammy's Adventures | $23,008 | -67.9% | 25 | +16 | $920 | $2,316,980 | 16 | Kinepolis Film Distribution (KFD) | false | false |
| 19 | 16 | Buried | $20,416 | -77.4% | 22 | -6 | $928 | $396,155 | 3 | Belga Films | false | false |
| 20 | - | Of Gods and Men | $20,224 | - | 26 | - | $777 | $1,213,975 | 11 | Benelux Film Distributors | false | false |
| 21 | 22 | You Will Meet a Tall Dark Stranger | $18,996 | -47.2% | 11 | - | $1,726 | $362,944 | 5 | Paradiso Entertainment | false | false |
| 22 | 20 | Eat Pray Love | $18,154 | -67.7% | 14 | -14 | $1,296 | $1,367,061 | 7 | Sony Pictures Releasing | false | false |
| 23 | 19 | Sarah's Key | $16,952 | -75.1% | 20 | - | $847 | $477,208 | 6 | Benelux Film Distributors | false | false |
| 24 | - | No et moi | $16,943 | - | 10 | - | $1,694 | $17,024 | 1 | Benelux Film Distributors | true | false |
| 25 | 15 | Charlie St. Cloud | $11,767 | -88.9% | 9 | -9 | $1,307 | $201,956 | 2 | Universal Pictures International (UPI) | false | false |
| 26 | 26 | The Princess of Montpensier | $7,065 | -67.7% | 5 | -7 | $1,413 | $83,883 | 3 | Universal Pictures International (UPI) | false | false |
| 27 | 21 | The Town | $7,056 | -83.6% | 8 | -12 | $882 | $1,229,114 | 8 | Warner Bros. | false | false |
| 28 | 27 | Turquaze | $6,205 | -63.1% | 5 | -2 | $1,241 | $366,467 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 29 | 31 | Oxygen | $5,988 | -34.1% | 15 | +2 | $399 | $888,323 | 11 | Kinepolis Film Distribution (KFD) | false | false |
| 30 | 28 | Black Venus | $5,227 | -59.3% | 5 | -3 | $1,045 | $43,852 | 3 | N/A | false | false |
| 31 | 32 | Draquila - L'Italia che trema | $4,867 | -36.2% | 4 | - | $1,216 | $16,552 | 2 | Alternative Films | false | false |
| 32 | - | 22nd of May | $4,835 | - | 5 | - | $967 | $4,835 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 33 | 30 | Beyond the Steppes | $4,531 | -55.7% | 5 | - | $906 | $16,747 | 2 | Benelux Film Distributors | false | false |
| 34 | 34 | Resident Evil: Afterlife | $3,664 | -33.3% | 2 | -1 | $1,832 | $971,137 | 8 | Belga Films | false | false |
| 35 | 33 | Poetry | $3,500 | -36.3% | 5 | - | $700 | $33,913 | 4 | Benelux Film Distributors | false | false |
| 36 | 38 | Kill Me Please | $3,227 | -33.3% | 4 | - | $806 | $49,116 | 3 | N/A | false | false |
| 37 | - | Lourdes | $2,831 | - | 7 | - | $404 | $2,831 | 1 | Benelux Film Distributors | true | false |
| 38 | - | Submarino | $2,684 | - | 4 | - | $671 | $2,998 | 1 | ABC Distribution | true | false |
| 39 | 37 | Illégal | $2,192 | -54.9% | 8 | -2 | $274 | $128,006 | 7 | N/A | false | false |
| 40 | 39 | Step Up 3D | $1,064 | -68.4% | 1 | -1 | $1,064 | $3,574,117 | 16 | Belga Films | false | false |
| 41 | 43 | Women Without Men | $627 | +454.9% | 1 | - | $627 | $29,039 | 12 | Benelux Film Distributors | false | false |
| 42 | 44 | Five Minutes of Heaven | $32 | -54.9% | 1 | - | $32 | $2,666 | 5 | Benelux Film Distributors | false | false |
