| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Despicable Me | $46,287 | -42.8% | 9 | - | $5,143 | $144,800 | 2 | United International Pictures | false | false |
| 2 | 2 | The Social Network | $19,358 | -44.7% | 5 | - | $3,871 | $73,665 | 2 | Sony Pictures Releasing | false | false |
| 3 | 3 | Eat Pray Love | $15,560 | -22.3% | 6 | - | $2,593 | $182,914 | 4 | Sony Pictures Releasing | false | false |
| 4 | 4 | Step Up 3D | $13,509 | +3.5% | 3 | - | $4,503 | $236,685 | 5 | N/A | false | false |
| 5 | - | The Town | $7,251 | - | 1 | - | $7,251 | $7,251 | 1 | Warner Bros. | true | false |
| 6 | 5 | Devil | $5,053 | -40.3% | 4 | - | $1,263 | $40,384 | 3 | United International Pictures | false | false |
| 7 | 6 | Wall Street: Money Never Sleeps | $3,735 | -28.8% | 4 | - | $933 | $91,770 | 5 | 20th Century Fox International | false | false |
| 8 | - | Moomins and the Comet Chase | $3,386 | - | 2 | - | $1,693 | $3,386 | 1 | N/A | true | false |
| 9 | 7 | The Other Guys | $2,542 | -41.8% | 3 | -1 | $847 | $67,269 | 6 | Sony Pictures Releasing | false | false |
| 10 | - | Agora | $2,525 | - | 1 | - | $2,525 | $2,525 | 1 | N/A | true | false |
