| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Eat Pray Love | $234,668 | -41.4% | 83 | - | $2,827 | $812,641 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Paranormal Activity 2 | $224,082 | - | 39 | - | $5,745 | $224,082 | 1 | Paramount Pictures International | true | false |
| 3 | - | Life as We Know It | $132,850 | - | 50 | - | $2,657 | $132,850 | 1 | Roadshow Films | true | false |
| 4 | 2 | The Town | $84,596 | -40.3% | 38 | - | $2,226 | $278,250 | 2 | Warner Bros. | false | false |
| 5 | 3 | Despicable Me | $66,696 | -38.9% | 82 | +4 | $813 | $2,997,528 | 6 | United International Pictures | false | false |
| 6 | - | Made in Dagenham | $45,155 | - | 36 | - | $1,254 | $51,085 | 1 | Paramount Pictures International | true | false |
| 7 | 4 | The Other Guys | $43,379 | -47.2% | 36 | -5 | $1,204 | $668,300 | 4 | Sony Pictures Releasing | false | false |
| 8 | - | Four Lions | $42,914 | - | 29 | - | $1,479 | $89,238 | 1 | Hopscotch Films | true | false |
| 9 | 5 | The Last Airbender | $34,141 | -49.5% | 58 | -3 | $588 | $1,482,571 | 5 | Paramount Pictures International | false | false |
| 10 | 7 | Legend of the Guardians: The Owls of Ga'Hoole | $33,214 | -30% | 78 | -1 | $425 | $323,671 | 3 | Roadshow Films | false | false |
| 11 | 6 | Dinner for Schmucks | $30,428 | -48.7% | 42 | +2 | $724 | $258,011 | 3 | Paramount Pictures International | false | false |
| 12 | 13 | The Insatiable Moon | $15,698 | +7.7% | 22 | -2 | $713 | $85,418 | 3 | Rialto Distribution | false | false |
| 13 | 8 | Vampires Suck | $14,710 | -55.7% | 32 | -5 | $459 | $372,212 | 4 | 20th Century Fox International | false | false |
| 14 | 9 | Wall Street: Money Never Sleeps | $14,439 | -54.7% | 33 | -14 | $437 | $525,109 | 5 | 20th Century Fox International | false | false |
| 15 | 12 | Farewell | $13,837 | -30.8% | 14 | - | $988 | $63,674 | 2 | Hopscotch Films | false | false |
| 16 | 10 | Cats & Dogs: The Revenge of Kitty Galore | $12,913 | -56.6% | 53 | -22 | $243 | $763,779 | 5 | Roadshow Films | false | false |
| 17 | 11 | Buried | $8,683 | -65.2% | 34 | -6 | $255 | $122,081 | 3 | Hoyts Distribution | false | false |
| 18 | 17 | Animal Kingdom | $7,196 | -32.4% | 16 | - | $449 | $153,876 | 6 | Madman Entertainment | false | false |
| 19 | 16 | The Sorcerer's Apprentice | $6,966 | -40.9% | 20 | -10 | $348 | $721,059 | 6 | Walt Disney Pictures | false | false |
| 20 | 15 | Inception | $6,648 | -48.3% | 15 | -8 | $443 | $4,437,734 | 14 | Warner Bros. | false | false |
| 21 | 23 | The Concert | $6,327 | -22.8% | 11 | -1 | $575 | $321,278 | 10 | Hopscotch Films | false | false |
| 22 | 14 | Grown Ups | $5,524 | -60.3% | 16 | -23 | $345 | $618,562 | 6 | Sony Pictures Releasing | false | false |
| 23 | 19 | Diary of a Wimpy Kid | $5,439 | -45% | 29 | -9 | $187 | $289,749 | 5 | 20th Century Fox International | false | false |
| 24 | 20 | I Am Love | $4,565 | -53.6% | 14 | -2 | $326 | $312,441 | 7 | Rialto Distribution | false | false |
| 25 | 24 | Harry Brown | $4,502 | -39.1% | 16 | -2 | $281 | $368,842 | 10 | Hoyts Distribution | false | false |
| 26 | 25 | Exit Through the Gift Shop | $4,125 | -34.7% | 9 | - | $458 | $180,964 | 7 | Madman Entertainment | false | false |
| 27 | 21 | Mother and Child | $3,895 | -58.7% | 12 | -3 | $324 | $172,142 | 6 | Hopscotch Films | false | false |
| 28 | - | Detective Dee: The Mystery of the Phantom Flame | $2,928 | - | 3 | - | $976 | $7,890 | 1 | Incubate | true | false |
| 29 | 22 | Tomorrow, When the War Began | $2,612 | -71.9% | 15 | -9 | $174 | $1,026,705 | 8 | Paramount Pictures International | false | false |
| 30 | - | Jhootha Hi Sahi | $1,853 | - | 3 | - | $617 | $1,853 | 1 | Mind Blowing Films | true | false |
| 31 | 27 | The Girl Who Played with Fire | $1,805 | -38.5% | 12 | - | $150 | $795,353 | 13 | Rialto Distribution | false | false |
| 32 | 40 | Legend of the Fist: The Return of Chen Zhen | $1,751 | +335.6% | 2 | - | $875 | $62,043 | 5 | N/A | false | false |
| 33 | 26 | A Prophet | $1,621 | -52.2% | 4 | - | $405 | $64,828 | 7 | Sony Pictures Releasing | false | false |
| 34 | 28 | The Expendables | $1,234 | -35.8% | 8 | -4 | $154 | $793,916 | 8 | Roadshow Films | false | false |
| 35 | 37 | With or Without You | $1,062 | +26.3% | 4 | - | $265 | $81,279 | 36 | - | false | false |
| 36 | 36 | The Runaways | $1,036 | +8.1% | 6 | - | $172 | $103,330 | 7 | Hoyts Distribution | false | false |
| 37 | 39 | I, Don Giovanni | $889 | +70.3% | 4 | +1 | $222 | $32,806 | 11 | - | false | false |
| 38 | 44 | Letters to Juliet | $807 | +976% | 1 | - | $807 | $372,866 | 24 | Hoyts Distribution | false | false |
| 39 | - | The Red Circle 2010 Re-release | $592 | - | 1 | - | $592 | $592 | 1 | - | true | false |
| 40 | 32 | Going the Distance | $484 | -59% | 6 | - | $80 | $299,203 | 8 | Warner Bros. | false | false |
| 41 | 34 | Skin | $471 | -54.4% | 5 | -1 | $94 | $126,454 | 12 | - | false | false |
| 42 | 31 | Beauty and the Beast 2010 3D Release | $457 | -62.4% | 1 | - | $457 | $60,233 | 11 | Walt Disney Pictures | false | false |
| 43 | 30 | Picture Me | $364 | -71.2% | 5 | -4 | $72 | $9,788 | 4 | Vendetta Films | false | false |
| 44 | - | I'm Still Here | $358 | - | 1 | - | $358 | $10,043 | 6 | Roadshow Films | false | false |
| 45 | 33 | South Solitary | $347 | -67.7% | 1 | - | $347 | $12,142 | 5 | Hoyts Distribution | false | false |
| 46 | - | The Gay Divorcee 2010 Re-release | $333 | - | 2 | - | $166 | $3,137 | 10 | - | false | false |
| 47 | - | Knock Out | $209 | - | 2 | - | $104 | $953 | 2 | - | false | false |
| 48 | - | Aakrosh | $185 | - | 2 | - | $92 | $5,148 | 2 | - | false | false |
| 49 | - | It's a Wonderful Afterlife | $126 | - | 1 | - | $126 | $42,104 | 9 | Hoyts Distribution | false | false |
| 50 | 35 | The Leopard 2010 Re-release | $117 | -88.4% | 1 | - | $117 | $1,287 | 2 | - | false | false |
| 51 | 41 | Touch of Evil 2010 Re-release | $75 | -59.7% | 1 | - | $75 | $1,302 | 3 | - | false | false |
| 52 | - | The Wages of Fear 2010 Re-release | $67 | - | 1 | - | $67 | $1,098 | 6 | - | false | false |
| 53 | 46 | The Big Red One 2010 Re-release | $12 | -47.8% | 1 | - | $12 | $468 | 4 | - | false | false |
