| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Despicable Me | $711,528 | - | 170 | - | $4,185 | $1,006,878 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Eat Pray Love | $503,166 | -17.2% | 91 | +1 | $5,529 | $1,627,799 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | RED | $488,062 | - | 79 | - | $6,178 | $488,062 | 1 | Entertainment One | true | false |
| 4 | - | Life as We Know It | $387,089 | - | 82 | - | $4,720 | $483,733 | 1 | Warner Bros. | true | false |
| 5 | 2 | Tirza | $184,849 | -26.4% | 69 | -1 | $2,678 | $990,675 | 3 | Independent Films | false | false |
| 6 | 7 | Fuchsia the Mini-Witch | $172,472 | +32.8% | 92 | +1 | $1,874 | $421,463 | 2 | Walt Disney Pictures | false | false |
| 7 | 3 | Legend of the Guardians: The Owls of Ga'Hoole | $139,954 | -32.1% | 156 | -6 | $897 | $897,065 | 3 | Warner Bros. | false | false |
| 8 | - | Briefgeheim | $130,817 | - | 100 | - | $1,308 | $130,817 | 1 | A-Film Distribution | true | false |
| 9 | 6 | The American | $104,474 | -19.9% | 35 | - | $2,984 | $1,265,116 | 5 | Benelux Film Distributors | false | false |
| 10 | 4 | Grown Ups | $100,843 | -47% | 51 | -8 | $1,977 | $2,010,825 | 6 | Sony Pictures Releasing | false | false |
| 11 | 5 | Wall Street: Money Never Sleeps | $92,083 | -49.6% | 69 | -19 | $1,334 | $1,254,140 | 4 | Warner Bros. | false | false |
| 12 | 8 | Inception | $85,508 | -30.3% | 56 | -20 | $1,526 | $9,603,041 | 13 | Warner Bros. | false | false |
| 13 | - | Sinterklaas en het pakjesmysterie | $55,105 | - | 106 | - | $519 | $67,069 | 1 | Entertainment One | true | false |
| 14 | 13 | Ernst & Bobbie en 'Het geheim van de Monta Rossa' | $49,778 | +4.5% | 101 | - | $492 | $149,224 | 2 | A-Film Distribution | false | false |
| 15 | 9 | Resident Evil: Afterlife | $46,751 | -58.3% | 25 | -24 | $1,870 | $872,799 | 4 | Entertainment One | false | false |
| 16 | - | The Killer Inside Me | $41,546 | - | 14 | - | $2,967 | $59,476 | 1 | Paradiso Entertainment | true | false |
| 17 | - | Happily Ever After | $36,939 | - | 47 | - | $785 | $45,917 | 1 | Independent Films | true | false |
| 18 | 10 | Devil | $35,221 | -55.1% | 17 | -18 | $2,071 | $795,614 | 5 | Universal Pictures International (UPI) | false | false |
| 19 | 19 | The Secret in Their Eyes | $25,533 | +9.6% | 15 | +1 | $1,702 | $559,880 | 8 | Wild Bunch Distribution | false | false |
| 20 | 14 | The New Daughter | $23,557 | -48.3% | 8 | - | $2,944 | $120,755 | 2 | Entertainment One | false | false |
