Italian 2010 Weekend 40
October 7-10, 2010
Key:New This Week
| Rank | LW | Release | Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | Welcome to the South | $6,242,776 | +19.3% | 568 | +36 | $10,990 | $15,179,819 | 2 | Medusa Distribuzione |
| 2 | - | Step Up 3D | $3,312,589 | - | 339 | - | $9,771 | $3,312,589 | 1 | Eagle Pictures |
| 3 | 2 | Inception | $1,660,531 | -34.6% | 401 | -184 | $4,140 | $11,210,195 | 3 | Warner Bros. |
| 4 | - | Knight and Day 2010 Re-release | $1,235,593 | - | 374 | - | $3,303 | $1,235,593 | 1 | 20th Century Fox International |
| 5 | - | The Town | $1,056,842 | - | 254 | - | $4,160 | $1,057,268 | 1 | Warner Bros. |
| 6 | 3 | The Last Airbender | $875,068 | -49.6% | 244 | -194 | $3,586 | $7,373,672 | 3 | United International Pictures |
| 7 | - | A Second Childhood | $509,731 | - | - | - | - | $509,731 | 1 | 01 Distribution |
| 8 | 4 | La passione di Laura | $312,843 | -53.7% | - | - | - | $2,862,673 | 3 | 01 Distribution |
| 9 | 7 | Grown Ups | $221,624 | -55.6% | 145 | -57 | $1,528 | $954,685 | 2 | Sony Pictures Releasing |
| 10 | 6 | Eat Pray Love | $177,264 | -66.8% | 98 | -190 | $1,808 | $5,189,130 | 4 | Sony Pictures Releasing |
| 11 | - | The City of Your Final Destination | $175,821 | - | 50 | - | $3,516 | $175,821 | 1 | Teodora Film |
| 12 | 11 | The Black Sheep | $153,681 | -0.8% | 66 | +1 | $2,328 | $449,470 | 2 | BIM Distribuzione |
| 13 | 5 | Vampires Suck | $132,185 | -76.6% | 98 | -160 | $1,348 | $6,016,946 | 4 | 20th Century Fox International |
| 14 | 8 | Sharm el Sheikh - Un'estate indimenticabile | $121,982 | -67.4% | 62 | -114 | $1,967 | $4,335,986 | 4 | Medusa Distribuzione |
| 15 | 9 | Shrek Forever After | $116,508 | -50.3% | 76 | -63 | $1,533 | $23,666,719 | 7 | United International Pictures |
| 16 | - | Step Up 2: The Streets | $95,138 | - | 3 | - | $31,712 | $5,367,895 | 130 | Moviemax |
| 17 | 10 | Cats & Dogs: The Revenge of Kitty Galore | $58,674 | -71.6% | 52 | -104 | $1,128 | $1,830,910 | 4 | Warner Bros. |
| 18 | 13 | The Solitude of Prime Numbers | $45,391 | -66.9% | 35 | -65 | $1,296 | $4,623,924 | 5 | Medusa Distribuzione |
| 19 | 12 | Horse | $41,188 | -70.2% | 36 | -50 | $1,144 | $268,668 | 2 | Fandango |
| 20 | 15 | Somewhere | $36,753 | -45% | 22 | -15 | $1,670 | $2,759,035 | 6 | Medusa Distribuzione |
| 21 | 21 | Toy Story 3 | $13,268 | +12.7% | 16 | -4 | $829 | $18,839,510 | 14 | Walt Disney Pictures |
| 22 | 20 | London River 2010 Re-release | $8,486 | -36.1% | 5 | -4 | $1,697 | $324,215 | 7 | BIM Distribuzione |
| 23 | 14 | Resident Evil: Afterlife | $7,724 | -94.3% | 8 | -59 | $965 | $5,227,039 | 5 | Sony Pictures Releasing |
| 24 | 16 | Law Abiding Citizen | $6,486 | -84% | 4 | -16 | $1,621 | $6,595,412 | 7 | N/A |
| 25 | 23 | The Secret in Their Eyes | $5,318 | -25.8% | 3 | -2 | $1,772 | $1,527,233 | 19 | Lucky Red |
| 26 | 19 | 20 Cigarettes | $5,101 | -64.6% | 5 | -11 | $1,020 | $270,417 | 5 | Istituto Luce |
| 27 | - | The First Beautiful Thing | $3,620 | - | 2 | - | $1,810 | $9,115,665 | 39 | Medusa Distribuzione |
| 28 | 28 | Howl | $3,466 | -29.4% | 3 | +1 | $1,155 | $305,337 | 7 | Fandango |
| 29 | 25 | The Sorcerer's Apprentice | $2,909 | -48.9% | 4 | -8 | $727 | $9,855,204 | 8 | Walt Disney Pictures |
| 30 | 24 | The Karate Kid | $2,815 | -52.8% | 9 | -5 | $312 | $2,567,977 | 6 | Sony Pictures Releasing |
| 31 | 33 | North Face | $2,811 | -8.7% | 3 | +1 | $937 | $132,781 | 7 | N/A |
| 32 | 26 | My Son, My Son, What Have Ye Done | $2,787 | -46.9% | 5 | -2 | $557 | $61,108 | 5 | N/A |
| 33 | 31 | Basilicata Coast to Coast | $2,580 | -37.2% | 2 | -1 | $1,290 | $4,616,522 | 27 | Eagle Pictures |
| 34 | 30 | The Expendables | $2,329 | -43.6% | 3 | -2 | $776 | $4,104,395 | 6 | 01 Distribution |
