| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Resident Evil: Afterlife | $325,597 | - | 35 | - | $9,302 | $325,597 | 1 | Belga Films | true | false |
| 2 | 1 | Wall Street: Money Never Sleeps | $237,140 | -17.8% | 43 | - | $5,514 | $636,271 | 2 | 20th Century Fox International | false | false |
| 3 | - | The Town | $221,649 | - | 25 | - | $8,865 | $319,823 | 1 | Warner Bros. | true | false |
| 4 | 6 | Of Gods and Men | $108,236 | +8.7% | 24 | +1 | $4,509 | $602,442 | 4 | Benelux Film Distributors | false | false |
| 5 | 5 | Grown Ups | $106,799 | +5.2% | 28 | - | $3,814 | $654,642 | 4 | Sony Pictures Releasing | false | false |
| 6 | 4 | Inception | $105,591 | +2% | 69 | -17 | $1,530 | $5,755,394 | 11 | Warner Bros. | false | false |
| 7 | 7 | Oxygen | $96,300 | +4.5% | 23 | - | $4,186 | $545,780 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 8 | 3 | The Expendables | $89,504 | -21.1% | 40 | -12 | $2,237 | $2,543,802 | 7 | Benelux Film Distributors | false | false |
| 9 | 2 | Piranha 3D | $79,359 | -36.1% | 29 | - | $2,736 | $973,598 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 10 | - | Dinner for Schmucks | $73,581 | - | 21 | - | $3,503 | $158,246 | 1 | Universal Pictures International (UPI) | true | false |
| 11 | 9 | A Turtle's Tale: Sammy's Adventures | $72,519 | -4.6% | 51 | - | $1,421 | $1,879,880 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 12 | - | Turquaze | $63,177 | - | 9 | - | $7,019 | $65,578 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 13 | 8 | Step Up 3D | $62,924 | -27.9% | 44 | -6 | $1,430 | $3,457,430 | 9 | Belga Films | false | false |
| 14 | 10 | Marmaduke | $61,118 | -16.3% | 45 | - | $1,358 | $1,080,867 | 7 | 20th Century Fox International | false | false |
| 15 | 11 | The Sorcerer's Apprentice | $56,902 | -18.3% | 38 | -6 | $1,497 | $1,985,671 | 8 | Walt Disney Pictures | false | false |
| 16 | - | I Am Love | $49,627 | - | 10 | - | $4,962 | $62,466 | 1 | Cinéart | true | false |
| 17 | - | Outside the Law | $49,057 | - | 21 | - | $2,336 | $69,133 | 1 | N/A | true | false |
| 18 | 14 | Tamara Drewe | $36,320 | -16.6% | 12 | -1 | $3,026 | $199,298 | 3 | Cinéart | false | false |
| 19 | 13 | The Last Exorcism | $35,059 | -35.1% | 11 | -1 | $3,187 | $204,345 | 3 | Cinéart | false | false |
| 20 | 12 | Twelve | $33,883 | -42.3% | 15 | -1 | $2,258 | $128,669 | 2 | Benelux Film Distributors | false | false |
| 21 | 15 | Toy Story 3 | $26,873 | -20.2% | 26 | -12 | $1,033 | $5,418,409 | 15 | Walt Disney Pictures | false | false |
| 22 | 17 | The Switch | $25,009 | -11.8% | 20 | -9 | $1,250 | $647,708 | 6 | Paradiso Entertainment | false | false |
| 23 | 20 | Going the Distance | $23,392 | -7.2% | 22 | -7 | $1,063 | $326,239 | 4 | Warner Bros. | false | false |
| 24 | 16 | Salt | $22,951 | -25.3% | 18 | -6 | $1,275 | $1,726,412 | 9 | Sony Pictures Releasing | false | false |
| 25 | 19 | Shrek Forever After | $22,591 | -16.1% | 33 | -12 | $684 | $4,865,775 | 12 | Universal Pictures International (UPI) | false | false |
| 26 | 18 | Cats & Dogs: The Revenge of Kitty Galore | $21,867 | -22.8% | 38 | -10 | $575 | $1,409,806 | 9 | Warner Bros. | false | false |
| 27 | 21 | The Last Airbender | $15,718 | -33.8% | 23 | -5 | $683 | $3,234,332 | 10 | Universal Pictures International (UPI) | false | false |
| 28 | 23 | The Karate Kid | $11,866 | -12.8% | 14 | -2 | $847 | $2,334,451 | 11 | Sony Pictures Releasing | false | false |
| 29 | 24 | The Tree | $10,847 | -14.1% | 12 | - | $903 | $216,519 | 6 | Cinéart | false | false |
| 30 | 26 | Four Lovers | $8,439 | -23% | 7 | -1 | $1,205 | $27,816 | 2 | Benelux Film Distributors | false | false |
| 31 | 29 | Tinker Bell and the Lost Treasure | $7,251 | -0.4% | 8 | -1 | $906 | $155,951 | 7 | Walt Disney Pictures | false | false |
| 32 | 27 | The Killer Inside Me | $6,445 | -28.3% | 9 | -1 | $716 | $169,502 | 7 | Paradiso Entertainment | false | false |
| 33 | 32 | Benda Bilili! | $5,792 | +2.2% | 4 | - | $1,448 | $14,707 | 2 | Cinéart | false | false |
| 34 | 31 | The Secret in Their Eyes | $5,414 | -10.2% | 7 | - | $773 | $325,654 | 17 | N/A | false | false |
| 35 | 22 | Avatar 2010 Special Edition | $4,384 | -69.5% | 4 | -8 | $1,096 | $100,975 | 4 | 20th Century Fox International | false | false |
| 36 | 28 | Solutions locales pour un désordre global | $3,558 | -53.9% | 6 | -1 | $593 | $45,829 | 4 | N/A | false | false |
| 37 | 30 | Letters to Juliet | $3,044 | -56.1% | 12 | -7 | $253 | $353,165 | 6 | Belga Films | false | false |
| 38 | 36 | Uncle Boonmee Who Can Recall His Past Lives | $2,969 | -14.9% | 6 | -1 | $494 | $49,213 | 5 | N/A | false | false |
| 39 | - | The Italian | $2,910 | - | 7 | - | $415 | $376,901 | 12 | Alternative Films | false | false |
| 40 | 34 | Single by Contract | $2,873 | -25.3% | 4 | - | $718 | $14,093 | 3 | N/A | false | false |
| 41 | 33 | The Disappearance of Alice Creed | $2,027 | -52.9% | 5 | -5 | $405 | $65,982 | 3 | Benelux Film Distributors | false | false |
| 42 | 38 | The Twilight Saga: Eclipse | $1,535 | -45% | 6 | +1 | $255 | $6,741,344 | 14 | Belga Films | false | false |
| 43 | 35 | Love Crime | $1,520 | -59.9% | 10 | - | $152 | $164,361 | 7 | Benelux Film Distributors | false | false |
| 44 | 39 | Women Without Men | $1,484 | -39.1% | 2 | -1 | $742 | $23,914 | 5 | Benelux Film Distributors | false | false |
| 45 | 40 | Law Abiding Citizen | $1,443 | +15.5% | 1 | - | $1,443 | $501,962 | 18 | Belga Films | false | false |
| 46 | 41 | Furry Vengeance | $1,331 | +12.7% | 3 | -4 | $443 | $202,744 | 11 | Belga Films | false | false |
| 47 | 43 | The Ghost Writer | $794 | +45.2% | 2 | +1 | $397 | $920,970 | 28 | Benelux Film Distributors | false | false |
| 48 | 37 | The Runaways | $430 | -86.5% | 2 | -3 | $215 | $22,768 | 3 | Belga Films | false | false |
