| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Other Guys | $3,097,109 | - | 441 | - | $7,022 | $3,097,109 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Devil | $1,262,380 | - | 338 | - | $3,734 | $1,262,380 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 1 | Resident Evil: Afterlife | $1,138,246 | -56.2% | 361 | - | $3,153 | $5,208,507 | 2 | Sony Pictures Releasing | false | false |
| 4 | 2 | Toy Story 3 | $911,670 | -21.6% | 455 | -21 | $2,003 | $112,287,643 | 9 | Walt Disney Pictures | false | false |
| 5 | 3 | Grown Ups | $803,567 | -29.6% | 387 | -10 | $2,076 | $9,851,950 | 4 | Sony Pictures Releasing | false | false |
| 6 | 5 | Tamara Drewe | $676,055 | -28.5% | 357 | -1 | $1,893 | $2,420,924 | 2 | Momentum Pictures | false | false |
| 7 | 4 | The Last Exorcism | $502,869 | -55.2% | 322 | +5 | $1,561 | $4,973,886 | 3 | Optimum Releasing | false | false |
| 8 | 13 | Marmaduke | $436,891 | -7% | 404 | -13 | $1,081 | $7,097,614 | 5 | 20th Century Fox International | false | false |
| 9 | 15 | Diary of a Wimpy Kid | $377,467 | -7.3% | 350 | -7 | $1,078 | $3,219,323 | 4 | 20th Century Fox International | false | false |
| 10 | 6 | Scott Pilgrim vs. the World | $364,704 | -46% | 295 | -79 | $1,236 | $7,525,837 | 4 | Universal Pictures International (UPI) | false | false |
| 11 | 7 | Going the Distance | $344,580 | -48.6% | 298 | -62 | $1,156 | $1,609,658 | 2 | Warner Bros. | false | false |
| 12 | 14 | Inception | $314,561 | -24.5% | 132 | -22 | $2,383 | $54,694,291 | 10 | Warner Bros. | false | false |
| 13 | 11 | Salt | $297,124 | -43.6% | 198 | -87 | $1,500 | $10,535,573 | 5 | Sony Pictures Releasing | false | false |
| 14 | 8 | Cyrus | $269,873 | -59.1% | 241 | -20 | $1,119 | $1,436,638 | 2 | 20th Century Fox International | false | false |
| 15 | 10 | The Expendables | $250,425 | -55.6% | 240 | -71 | $1,043 | $15,058,854 | 5 | Lionsgate Films | false | false |
