| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Wall Street: Money Never Sleeps | $288,553 | - | 43 | - | $6,710 | $304,430 | 1 | 20th Century Fox International | true | false |
| 2 | 3 | Piranha 3D | $124,140 | -15.7% | 29 | -1 | $4,280 | $806,517 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 3 | 1 | The Expendables | $113,463 | -31.9% | 52 | - | $2,181 | $2,259,614 | 6 | Benelux Film Distributors | false | false |
| 4 | 2 | Inception | $103,493 | -31.5% | 86 | -6 | $1,203 | $5,219,730 | 10 | Warner Bros. | false | false |
| 5 | 4 | Grown Ups | $101,510 | -23.9% | 28 | - | $3,625 | $526,965 | 3 | Sony Pictures Releasing | false | false |
| 6 | 5 | Of Gods and Men | $99,545 | -13.6% | 23 | +3 | $4,328 | $420,375 | 3 | Benelux Film Distributors | false | false |
| 7 | 6 | Oxygen | $92,134 | -18.1% | 23 | +1 | $4,005 | $393,841 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 8 | 7 | Step Up 3D | $87,242 | -21.1% | 50 | -4 | $1,744 | $3,129,748 | 8 | Belga Films | false | false |
| 9 | 13 | A Turtle's Tale: Sammy's Adventures | $76,055 | +30.8% | 51 | -4 | $1,491 | $1,650,850 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 10 | 14 | Marmaduke | $73,034 | +26.3% | 45 | -3 | $1,622 | $933,424 | 6 | 20th Century Fox International | false | false |
| 11 | 8 | The Sorcerer's Apprentice | $69,636 | -24.1% | 44 | -7 | $1,582 | $1,768,770 | 7 | Walt Disney Pictures | false | false |
| 12 | - | Twelve | $58,682 | - | 16 | - | $3,667 | $72,781 | 1 | Benelux Film Distributors | true | false |
| 13 | 9 | The Last Exorcism | $54,017 | -39.7% | 12 | - | $4,501 | $145,264 | 2 | Cinéart | false | false |
| 14 | 10 | Tamara Drewe | $43,528 | -34.5% | 13 | - | $3,348 | $137,710 | 2 | Cinéart | false | false |
| 15 | 18 | Toy Story 3 | $33,693 | +8.1% | 38 | -5 | $886 | $4,998,600 | 14 | Walt Disney Pictures | false | false |
| 16 | 11 | Salt | $30,739 | -52.7% | 24 | -12 | $1,280 | $1,695,872 | 8 | Sony Pictures Releasing | false | false |
| 17 | 15 | The Switch | $28,369 | -44.5% | 29 | +1 | $978 | $570,769 | 5 | Paradiso Entertainment | false | false |
| 18 | 21 | Cats & Dogs: The Revenge of Kitty Galore | $28,323 | +14.3% | 48 | -11 | $590 | $1,284,862 | 8 | Warner Bros. | false | false |
| 19 | 19 | Shrek Forever After | $26,923 | -8.5% | 45 | -5 | $598 | $4,495,639 | 11 | Universal Pictures International (UPI) | false | false |
| 20 | 12 | Going the Distance | $25,220 | -60.4% | 29 | -1 | $869 | $273,854 | 3 | Warner Bros. | false | false |
| 21 | 16 | The Last Airbender | $23,740 | -36.8% | 28 | -10 | $847 | $2,980,326 | 9 | Universal Pictures International (UPI) | false | false |
| 22 | 20 | Avatar 2010 Special Edition | $14,355 | -42.3% | 12 | -2 | $1,196 | $89,713 | 3 | 20th Century Fox International | false | false |
| 23 | 26 | The Karate Kid | $13,601 | -10.3% | 16 | -6 | $850 | $2,320,908 | 10 | Sony Pictures Releasing | false | false |
| 24 | 25 | The Tree | $12,634 | -17.4% | 12 | +1 | $1,052 | $186,894 | 5 | Cinéart | false | false |
| 25 | 22 | Knight and Day 2010 Re-release | $12,312 | -42.2% | 20 | -7 | $615 | $2,289,600 | 9 | 20th Century Fox International | false | false |
| 26 | - | Four Lovers | $10,956 | - | 8 | - | $1,369 | $17,998 | 1 | Benelux Film Distributors | true | false |
| 27 | 24 | The Killer Inside Me | $8,994 | -43.4% | 10 | - | $899 | $147,675 | 6 | Paradiso Entertainment | false | false |
| 28 | 34 | Solutions locales pour un désordre global | $7,724 | +60.9% | 7 | +1 | $1,103 | $37,069 | 3 | N/A | false | false |
| 29 | 28 | Tinker Bell and the Lost Treasure | $7,281 | -23.5% | 9 | -4 | $809 | $135,893 | 6 | Walt Disney Pictures | false | false |
| 30 | 23 | Letters to Juliet | $6,940 | -60.6% | 19 | -1 | $365 | $322,327 | 5 | Belga Films | false | false |
| 31 | 30 | The Secret in Their Eyes | $6,032 | +8.8% | 7 | - | $861 | $295,095 | 16 | N/A | false | false |
| 32 | - | Benda Bilili! | $5,669 | - | 4 | - | $1,417 | $5,891 | 1 | Cinéart | true | false |
| 33 | 17 | The Disappearance of Alice Creed | $4,304 | -88% | 10 | -2 | $430 | $57,379 | 2 | Benelux Film Distributors | false | false |
| 34 | 33 | Single by Contract | $3,844 | -29.5% | 4 | - | $961 | $9,963 | 2 | N/A | false | false |
| 35 | 29 | Love Crime | $3,786 | -42.5% | 10 | -7 | $378 | $151,089 | 6 | Benelux Film Distributors | false | false |
| 36 | 31 | Uncle Boonmee Who Can Recall His Past Lives | $3,489 | -36.6% | 7 | -1 | $498 | $41,834 | 4 | N/A | false | false |
| 37 | 27 | The Runaways | $3,178 | -74.1% | 5 | -2 | $635 | $19,018 | 2 | Belga Films | false | false |
| 38 | 32 | The Twilight Saga: Eclipse | $2,791 | -49% | 5 | -9 | $558 | $6,259,361 | 13 | Belga Films | false | false |
| 39 | 37 | Women Without Men | $2,438 | -12.5% | 3 | - | $812 | $19,433 | 4 | Benelux Film Distributors | false | false |
| 40 | 43 | Law Abiding Citizen | $1,249 | -30.6% | 1 | - | $1,249 | $464,564 | 17 | Belga Films | false | false |
| 41 | 39 | Furry Vengeance | $1,181 | -55.4% | 7 | +1 | $168 | $186,831 | 10 | Belga Films | false | false |
| 42 | 40 | The Fourth Kind | $640 | -71.4% | 3 | -1 | $213 | $100,808 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 43 | 46 | The Ghost Writer | $547 | -53.3% | 1 | -2 | $547 | $852,365 | 27 | Benelux Film Distributors | false | false |
| 44 | 44 | The Last Station 2010 Re-release | $488 | -70.7% | 3 | -1 | $162 | $55,426 | 15 | Belga Films | false | false |
| 45 | 41 | Ondine | $362 | -83.3% | 3 | -1 | $120 | $32,605 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 46 | 45 | Get Him to the Greek | $313 | -79.3% | 4 | +1 | $78 | $55,973 | 6 | Universal Pictures International (UPI) | false | false |
| 47 | 47 | The Blonde with Bare Breasts | $213 | -54.1% | 2 | -4 | $106 | $6,577 | 5 | Benelux Film Distributors | false | false |
