| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Expendables | $30,931 | -42.4% | 4 | - | $7,732 | $179,683 | 2 | N/A | false | false |
| 2 | - | Step Up 3D | $24,672 | - | 5 | - | $4,934 | $25,019 | 1 | N/A | true | false |
| 3 | - | Scott Pilgrim vs. the World | $13,953 | - | 3 | - | $4,651 | $23,523 | 1 | United International Pictures | true | false |
| 4 | 2 | Cats & Dogs: The Revenge of Kitty Galore | $12,943 | -25.4% | 5 | -1 | $2,588 | $38,334 | 2 | Warner Bros. | false | false |
| 5 | 3 | Salt | $9,256 | -42% | 4 | -2 | $2,314 | $154,827 | 3 | Sony Pictures Releasing | false | false |
| 6 | 4 | Inception | $6,629 | -30.7% | 4 | -1 | $1,657 | $449,575 | 6 | Warner Bros. | false | false |
| 7 | 5 | Letters to Juliet | $5,849 | -37.7% | 3 | -1 | $1,949 | $32,156 | 2 | N/A | false | false |
| 8 | 6 | Shrek Forever After | $4,674 | -27.7% | 7 | +2 | $667 | $289,142 | 7 | United International Pictures | false | false |
| 9 | 7 | Vampires Suck | $3,871 | -38.5% | 3 | - | $1,290 | $17,989 | 2 | 20th Century Fox International | false | false |
| 10 | 9 | The Karate Kid | $3,200 | -39.3% | 3 | -1 | $1,066 | $133,443 | 5 | Sony Pictures Releasing | false | false |
| 11 | - | The Human Centipede (First Sequence) | $3,041 | - | 1 | - | $3,041 | $3,041 | 1 | N/A | true | false |
| 12 | 8 | The Last Airbender | $2,762 | -53.9% | 4 | -1 | $690 | $57,054 | 3 | United International Pictures | false | false |
| 13 | 11 | Toy Story 3 | $2,170 | -16.3% | 2 | -1 | $1,085 | $420,922 | 11 | Walt Disney Pictures | false | false |
| 14 | 10 | The Sorcerer's Apprentice | $1,407 | -62.3% | 2 | -3 | $703 | $85,889 | 4 | Walt Disney Pictures | false | false |
| 15 | 12 | The Ugly Duckling and Me! | $612 | -9.3% | 2 | -1 | $306 | $7,890 | 4 | N/A | false | false |
| 16 | 15 | Knight and Day 2010 Re-release | $252 | -7% | 1 | -5 | $252 | $112,888 | 8 | 20th Century Fox International | false | false |
| 17 | 16 | 22 Bullets | $68 | -55.3% | 1 | - | $68 | $11,336 | 4 | N/A | false | false |
