| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Last Airbender | $31,804 | - | 6 | - | $5,300 | $35,315 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | The Expendables | $23,297 | -33% | 6 | - | $3,882 | $97,812 | 2 | Incognito Films | false | false |
| 3 | 2 | Cats & Dogs: The Revenge of Kitty Galore | $18,006 | -12.8% | 8 | - | $2,250 | $137,514 | 3 | Warner Bros. | false | false |
| 4 | - | Vampires Suck | $12,860 | - | 4 | - | $3,215 | $12,860 | 1 | Universal Pictures International (UPI) | true | false |
| 5 | 5 | Inception | $11,014 | -5.7% | 6 | - | $1,835 | $251,085 | 5 | - | false | false |
| 6 | 3 | The Sorcerer's Apprentice | $10,437 | -31.8% | 6 | - | $1,739 | $42,546 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 4 | Salt | $8,601 | -35.4% | 7 | - | $1,228 | $102,422 | 3 | ACME | false | false |
| 8 | - | The Girl with the Dragon Tattoo | $3,965 | - | 4 | - | $991 | $5,893 | 1 | Incognito Films | true | false |
| 9 | 9 | Toy Story 3 | $3,313 | +10.7% | 8 | -2 | $414 | $174,898 | 7 | Universal Pictures International (UPI) | false | false |
| 10 | 6 | Get Him to the Greek | $2,989 | -25.4% | 5 | - | $597 | $32,797 | 3 | Universal Pictures International (UPI) | false | false |
| 11 | 8 | Shrek Forever After | $2,814 | -7.9% | 7 | - | $402 | $602,421 | 12 | Universal Pictures International (UPI) | false | false |
| 12 | 11 | Predators | $2,496 | -0.5% | 6 | - | $416 | $61,409 | 4 | Universal Pictures International (UPI) | false | false |
| 13 | 10 | Grown Ups | $2,302 | -16.2% | 4 | - | $575 | $48,207 | 4 | Sony Pictures Releasing | false | false |
| 14 | 12 | Mother and Child | $1,739 | -17.9% | 2 | - | $869 | $7,164 | 2 | MEED Films | false | false |
| 15 | 7 | StreetDance 2 | $1,640 | -54.4% | 2 | -1 | $820 | $187,542 | 9 | N/A | false | false |
| 16 | 16 | Knight and Day 2010 Re-release | $636 | +421.3% | 2 | -5 | $318 | $98,308 | 6 | Universal Pictures International (UPI) | false | false |
| 17 | 17 | The Young Victoria | $580 | +400% | 2 | -1 | $290 | $42,021 | 10 | N/A | false | false |
| 18 | 14 | Letters to Juliet | $520 | +34.7% | 2 | +1 | $260 | $27,958 | 5 | ACME | false | false |
| 19 | - | Ice Age: Dawn of the Dinosaurs | $279 | - | 2 | - | $139 | $1,258,774 | 60 | Universal Pictures International (UPI) | false | false |
| 20 | 15 | The Twilight Saga: Eclipse | $192 | -30.2% | 1 | -1 | $192 | $278,952 | 8 | ACME | false | false |
| 21 | - | I Always Wanted to Be a Gangster | $182 | - | 1 | - | $182 | $5,896 | 78 | Universal Pictures International (UPI) | false | false |
| 22 | 24 | Alice in Wonderland | $151 | +586.4% | 2 | +1 | $75 | $490,893 | 25 | Universal Pictures International (UPI) | false | false |
| 23 | 18 | How to Train Your Dragon | $119 | +17.8% | 1 | -1 | $119 | $327,180 | 21 | Universal Pictures International (UPI) | false | false |
| 24 | 21 | Mid-August Lunch | $83 | +72.9% | 1 | - | $83 | $9,967 | 47 | N/A | false | false |
| 25 | - | The A-Team | $78 | - | 2 | - | $39 | $49,732 | 11 | Universal Pictures International (UPI) | false | false |
| 26 | - | Tulpan | $75 | - | 1 | - | $75 | $455 | 4 | - | false | false |
| 27 | 19 | Alvin and the Chipmunks: The Squeakquel | $59 | -36.6% | 1 | - | $59 | $294,593 | 35 | Universal Pictures International (UPI) | false | false |
| 28 | 25 | Small Crime | $56 | +700% | 1 | - | $56 | $3,332 | 15 | N/A | false | false |
| 29 | - | The Princess and the Frog | $54 | - | 1 | - | $54 | $247,990 | 30 | Universal Pictures International (UPI) | false | false |
| 30 | 22 | Prince of Persia: The Sands of Time | $45 | +36.4% | 1 | - | $45 | $169,314 | 13 | Universal Pictures International (UPI) | false | false |
| 31 | 23 | Shrek the Third | $43 | +48.3% | 1 | - | $43 | $579,094 | 168 | Universal Pictures International (UPI) | false | false |
| 32 | - | WALL·E | $29 | - | 1 | - | $29 | $418,374 | 110 | Universal Pictures International (UPI) | false | false |
| 33 | - | G-Force | $19 | - | 1 | - | $19 | $273,851 | 49 | Universal Pictures International (UPI) | false | false |
