| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Last Airbender | $965,004 | - | 185 | - | $5,216 | $966,738 | 1 | United International Pictures | true | false |
| 2 | 2 | Inception | $248,123 | -30.6% | 112 | -5 | $2,215 | $2,155,939 | 4 | Warner Bros. | false | false |
| 3 | 1 | Cats & Dogs: The Revenge of Kitty Galore | $193,988 | -57.4% | 107 | -39 | $1,812 | $1,625,272 | 3 | Warner Bros. | false | false |
| 4 | 3 | Despicable Me | $97,152 | -53.4% | 92 | -27 | $1,056 | $2,487,693 | 5 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Oceans | $93,019 | -13.2% | 34 | -1 | $2,735 | $243,579 | 2 | Cine Colombia | false | false |
| 6 | 5 | Grown Ups | $90,872 | -14.1% | 49 | -1 | $1,854 | $645,070 | 4 | Sony Pictures Releasing | false | false |
| 7 | 6 | Predators | $45,377 | -57% | 48 | -8 | $945 | $441,041 | 3 | 20th Century Fox International | false | false |
| 8 | 7 | The Sorcerer's Apprentice | $41,731 | -53.9% | 37 | -36 | $1,127 | $2,875,534 | 7 | Walt Disney Pictures | false | false |
| 9 | - | Halloween II | $33,233 | - | 22 | - | $1,510 | $33,233 | 1 | Cine Colombia | true | false |
| 10 | 8 | Shrek Forever After | $18,865 | -66.7% | 39 | -16 | $483 | $6,650,943 | 8 | United International Pictures | false | false |
| 11 | 9 | Green Zone 2010 Re-release | $17,330 | -55% | 20 | -5 | $866 | $69,099 | 2 | United International Pictures | false | false |
| 12 | 11 | Cherry Blossoms | $4,209 | -37.4% | 5 | -2 | $841 | $107,034 | 8 | Cine Colombia | false | false |
| 13 | 12 | Toy Story 3 | $4,124 | -21.8% | 15 | -4 | $274 | $10,515,160 | 11 | Walt Disney Pictures | false | false |
| 14 | 10 | Salt | $3,280 | -80.2% | 5 | -14 | $656 | $820,023 | 6 | Sony Pictures Releasing | false | false |
| 15 | - | Two Lovers | $3,241 | - | 1 | - | $3,241 | $52,003 | 12 | Cine Colombia | false | false |
