| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Inception | $217,780 | +653.9% | 7 | - | $31,111 | $198,153 | 3 | - | false | false |
| 2 | - | Salt | $37,708 | - | 7 | - | $5,386 | $37,708 | 1 | ACME | true | false |
| 3 | - | Cats & Dogs: The Revenge of Kitty Galore | $32,960 | - | 8 | - | $4,120 | $39,580 | 1 | Warner Bros. | true | false |
| 4 | - | Get Him to the Greek | $9,043 | - | 5 | - | $1,808 | $10,428 | 1 | Universal Pictures International (UPI) | true | false |
| 5 | 2 | Predators | $8,420 | -60.2% | 6 | - | $1,403 | $46,930 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 3 | Grown Ups | $7,353 | -29.6% | 5 | - | $1,470 | $33,739 | 2 | Sony Pictures Releasing | false | false |
| 7 | 4 | Toy Story 3 | $4,870 | -53% | 10 | -3 | $487 | $167,123 | 5 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | StreetDance 2 | $3,904 | -40.1% | 4 | - | $976 | $179,320 | 7 | N/A | false | false |
| 9 | 7 | The Twilight Saga: Eclipse | $2,629 | -55.5% | 4 | -3 | $657 | $288,917 | 6 | ACME | false | false |
| 10 | 5 | Knight and Day 2010 Re-release | $2,095 | -70.8% | 7 | - | $299 | $98,860 | 4 | Universal Pictures International (UPI) | false | false |
| 11 | 9 | Letters to Juliet | $1,788 | -54.4% | 3 | -1 | $596 | $25,418 | 3 | ACME | false | false |
| 12 | 10 | Shrek Forever After | $1,385 | -59.7% | 5 | -2 | $277 | $618,512 | 10 | Universal Pictures International (UPI) | false | false |
| 13 | 8 | Turtle: The Incredible Journey | $888 | -77.9% | 2 | -3 | $444 | $23,714 | 3 | N/A | false | false |
| 14 | - | Mid-August Lunch | $596 | - | 1 | - | $596 | $9,909 | 45 | N/A | false | false |
| 15 | 14 | The Young Victoria | $313 | -7.1% | 2 | - | $156 | $42,141 | 8 | N/A | false | false |
| 16 | - | Shrek the Third | $297 | - | 1 | - | $297 | $606,371 | 166 | Universal Pictures International (UPI) | false | false |
| 17 | - | It's Complicated | $141 | - | 1 | - | $141 | $95,087 | 30 | Universal Pictures International (UPI) | false | false |
| 18 | 19 | Coco Before Chanel | $119 | +38.4% | 1 | - | $119 | $85,332 | 23 | N/A | false | false |
| 19 | 21 | Alvin and the Chipmunks: The Squeakquel | $93 | +106.7% | 1 | -1 | $93 | $308,346 | 33 | Universal Pictures International (UPI) | false | false |
| 20 | - | Robin Hood | $91 | - | 2 | - | $45 | $202,126 | 13 | Universal Pictures International (UPI) | false | false |
| 21 | - | When in Rome | $41 | - | 1 | - | $41 | $55,449 | 21 | Universal Pictures International (UPI) | false | false |
| 22 | 25 | Bad Lieutenant: Port of Call New Orleans | $40 | +344.4% | 1 | - | $40 | $28,812 | 25 | N/A | false | false |
| 23 | - | The Princess and the Frog | $34 | - | 1 | - | $34 | $259,771 | 28 | Universal Pictures International (UPI) | false | false |
| 24 | - | Tulpan | $23 | - | 1 | - | $23 | $288 | 2 | - | false | false |
| 25 | 20 | Dorian Gray | $14 | -74.5% | 1 | - | $14 | $35,123 | 15 | N/A | false | false |
| 26 | - | The Wolfman | $10 | - | 1 | - | $10 | $57,373 | 26 | Universal Pictures International (UPI) | false | false |
| 27 | 23 | Nanny McPhee Returns | $3 | -82.4% | 1 | - | $3 | $24,573 | 15 | Universal Pictures International (UPI) | false | false |
