| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Step Up 3D | $685,540 | - | 68 | - | $10,081 | $685,540 | 1 | Belga Films | true | false |
| 2 | 2 | Inception | $615,665 | -19.9% | 92 | - | $6,692 | $3,004,624 | 3 | Warner Bros. | false | false |
| 3 | 1 | The Last Airbender | $544,681 | -46.9% | 58 | -3 | $9,391 | $1,807,675 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | - | Salt | $458,977 | - | 46 | - | $9,977 | $458,977 | 1 | Sony Pictures Releasing | true | false |
| 5 | 3 | Knight and Day 2010 Re-release | $444,603 | -33.5% | 85 | - | $5,230 | $1,406,269 | 2 | 20th Century Fox International | false | false |
| 6 | 4 | Shrek Forever After | $352,304 | -24.4% | 116 | -16 | $3,037 | $3,689,755 | 4 | Universal Pictures International (UPI) | false | false |
| 7 | - | Cats & Dogs: The Revenge of Kitty Galore | $320,851 | - | 71 | - | $4,519 | $345,929 | 1 | Warner Bros. | true | false |
| 8 | 5 | Toy Story 3 | $309,787 | -19% | 102 | -4 | $3,037 | $4,031,024 | 7 | Walt Disney Pictures | false | false |
| 9 | 6 | The Karate Kid | $270,260 | -26.9% | 60 | - | $4,504 | $1,657,328 | 3 | Sony Pictures Releasing | false | false |
| 10 | - | A Turtle's Tale: Sammy's Adventures | $200,745 | - | 30 | - | $6,691 | $209,029 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 11 | 7 | The Twilight Saga: Eclipse | $190,868 | -32.8% | 86 | -4 | $2,219 | $5,994,713 | 6 | Belga Films | false | false |
| 12 | - | With Love... from the Age of Reason | $55,378 | - | 13 | - | $4,259 | $68,095 | 1 | Cinéart | true | false |
| 13 | 8 | Killers | $52,118 | -27.6% | 21 | -12 | $2,481 | $896,636 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 14 | 10 | The Italian | $37,917 | -13.6% | 11 | - | $3,447 | $269,110 | 4 | Alternative Films | false | false |
| 15 | 9 | Predators | $33,218 | -45% | 28 | -7 | $1,186 | $664,800 | 4 | 20th Century Fox International | false | false |
| 16 | 12 | Furry Vengeance | $21,860 | -30.8% | 15 | -7 | $1,457 | $141,336 | 3 | Belga Films | false | false |
| 17 | 11 | The Fourth Kind | $19,154 | -52.6% | 12 | -3 | $1,596 | $74,825 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 18 | 14 | Sex and the City 2 | $15,948 | -34% | 11 | -5 | $1,449 | $2,679,611 | 10 | Warner Bros. | false | false |
| 19 | 17 | My Afternoons with Margueritte | $11,331 | -24.3% | 12 | -5 | $944 | $198,270 | 7 | Cinéart | false | false |
| 20 | 13 | Splice 2010 Re-release | $8,481 | -72.9% | 12 | -3 | $706 | $76,570 | 2 | Benelux Film Distributors | false | false |
| 21 | 19 | Babies | $8,246 | -13% | 7 | -1 | $1,178 | $40,042 | 3 | Cinéart | false | false |
| 22 | 15 | Robin Hood | $6,885 | -60% | 2 | -7 | $3,442 | $3,207,998 | 13 | Universal Pictures International (UPI) | false | false |
| 23 | 16 | The Back-up Plan | $6,210 | -62.9% | 5 | -6 | $1,242 | $352,040 | 7 | Sony Pictures Releasing | false | false |
| 24 | 18 | The A-Team | $5,952 | -43.5% | 10 | -12 | $595 | $1,180,013 | 8 | 20th Century Fox International | false | false |
| 25 | 22 | Me Too | $5,195 | -15.6% | 4 | - | $1,298 | $19,518 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 26 | 21 | Horn of Plenty 2010 Re-release | $4,723 | -23.6% | 2 | -1 | $2,361 | $12,478 | 2 | N/A | false | false |
| 27 | 24 | Baaria | $3,180 | -11.6% | 7 | - | $454 | $42,882 | 6 | Paradiso Entertainment | false | false |
| 28 | 23 | Wandering Streams | $3,142 | -35.5% | 3 | -4 | $1,047 | $20,406 | 4 | N/A | false | false |
| 29 | 25 | Law Abiding Citizen | $2,865 | -17.4% | 2 | - | $1,432 | $459,090 | 10 | Belga Films | false | false |
| 30 | - | Love Like Poison | $2,779 | - | 1 | - | $2,779 | $2,779 | 1 | Les Films de l'Elysée | true | false |
| 31 | 36 | The Last Station 2010 Re-release | $2,548 | +351% | 4 | +1 | $637 | $31,432 | 8 | Belga Films | false | false |
| 32 | 29 | The Illusionist | $2,057 | +18.7% | 4 | +1 | $514 | $49,068 | 8 | Paradiso Entertainment | false | false |
| 33 | 27 | Cairo Time | $1,916 | -13.3% | 3 | -2 | $638 | $17,699 | 5 | ABC Distribution | false | false |
| 34 | 26 | Hanni & Nanni | $1,866 | -44.3% | 3 | - | $622 | $33,775 | 8 | Universal Pictures International (UPI) | false | false |
| 35 | 35 | The Ghost Writer | $1,389 | +79% | 2 | - | $694 | $864,894 | 20 | Benelux Film Distributors | false | false |
| 36 | 32 | Chicas | $1,087 | +10.1% | 3 | - | $362 | $7,092 | 4 | Benelux Film Distributors | false | false |
| 37 | 28 | On Tour | $1,042 | -46.5% | 4 | -2 | $260 | $19,656 | 6 | N/A | false | false |
| 38 | 31 | Alamar | $608 | -48% | 4 | - | $152 | $14,702 | 5 | Benelux Film Distributors | false | false |
| 39 | 34 | Agora | $295 | -66.1% | 2 | -1 | $147 | $167,495 | 16 | Benelux Film Distributors | false | false |
