| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Last Airbender | $1,024,926 | - | 61 | - | $16,802 | $1,032,531 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Inception | $768,751 | -23.8% | 92 | +6 | $8,355 | $2,160,727 | 2 | Warner Bros. | false | false |
| 3 | - | Knight and Day 2010 Re-release | $668,264 | - | 85 | - | $7,861 | $770,436 | 1 | 20th Century Fox International | true | false |
| 4 | 2 | Shrek Forever After | $465,822 | -36.9% | 132 | - | $3,528 | $3,201,034 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Toy Story 3 | $382,652 | -18% | 106 | -2 | $3,609 | $3,606,860 | 6 | Walt Disney Pictures | false | false |
| 6 | 3 | The Karate Kid | $369,624 | -46.4% | 60 | - | $6,160 | $1,281,934 | 2 | Sony Pictures Releasing | false | false |
| 7 | 5 | The Twilight Saga: Eclipse | $284,071 | -35.4% | 90 | -2 | $3,156 | $5,699,674 | 5 | Belga Films | false | false |
| 8 | 6 | Killers | $71,951 | -50.1% | 33 | -6 | $2,180 | $821,617 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 9 | 7 | Predators | $60,411 | -56.6% | 35 | - | $1,726 | $611,723 | 3 | 20th Century Fox International | false | false |
| 10 | 8 | The Italian | $43,862 | -37% | 11 | - | $3,987 | $217,823 | 3 | Alternative Films | false | false |
| 11 | - | The Fourth Kind | $40,386 | - | 15 | - | $2,692 | $40,386 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 12 | 9 | Furry Vengeance | $31,574 | -38.4% | 22 | -6 | $1,435 | $107,584 | 2 | Belga Films | false | false |
| 13 | - | Splice 2010 Re-release | $31,268 | - | 15 | - | $2,084 | $57,062 | 1 | Benelux Film Distributors | true | false |
| 14 | 10 | Sex and the City 2 | $24,165 | -41.1% | 16 | -16 | $1,510 | $2,654,485 | 9 | Warner Bros. | false | false |
| 15 | 14 | Robin Hood | $17,226 | -35.3% | 9 | -6 | $1,914 | $3,196,022 | 12 | Universal Pictures International (UPI) | false | false |
| 16 | 13 | The Back-up Plan | $16,723 | -37.8% | 11 | -3 | $1,520 | $340,974 | 6 | Sony Pictures Releasing | false | false |
| 17 | 16 | My Afternoons with Margueritte | $14,967 | -13.1% | 17 | - | $880 | $180,539 | 6 | Cinéart | false | false |
| 18 | 11 | The A-Team | $10,537 | -74.2% | 22 | -20 | $478 | $1,171,592 | 7 | 20th Century Fox International | false | false |
| 19 | 17 | Babies | $9,473 | -21.9% | 8 | - | $1,184 | $28,660 | 2 | Cinéart | false | false |
| 20 | 12 | Prince of Persia: The Sands of Time | $7,704 | -72.6% | 9 | -4 | $856 | $2,245,926 | 11 | Walt Disney Pictures | false | false |
| 21 | - | Horn of Plenty 2010 Re-release | $6,180 | - | 3 | - | $2,060 | $6,301 | 1 | N/A | true | false |
| 22 | - | Me Too | $6,157 | - | 4 | - | $1,539 | $11,201 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 23 | 23 | Wandering Streams | $4,868 | +20.8% | 7 | +3 | $695 | $15,553 | 3 | N/A | false | false |
| 24 | 21 | Baaria | $3,597 | -20.1% | 7 | -1 | $513 | $37,119 | 5 | Paradiso Entertainment | false | false |
| 25 | 19 | Law Abiding Citizen | $3,467 | -58.4% | 2 | -2 | $1,733 | $455,179 | 9 | Belga Films | false | false |
| 26 | 22 | Hanni & Nanni | $3,351 | -22.5% | 3 | -1 | $1,117 | $31,098 | 7 | Universal Pictures International (UPI) | false | false |
| 27 | 29 | Cairo Time | $2,211 | -24.9% | 5 | +1 | $442 | $15,029 | 4 | ABC Distribution | false | false |
| 28 | 26 | On Tour | $1,947 | -44.8% | 6 | +2 | $324 | $18,053 | 5 | N/A | false | false |
| 29 | 32 | The Illusionist | $1,733 | +13.6% | 3 | - | $577 | $44,932 | 7 | Paradiso Entertainment | false | false |
| 30 | 20 | Brooklyn's Finest 2010 Re-release | $1,379 | -78% | 3 | -1 | $459 | $272,359 | 8 | Benelux Film Distributors | false | false |
| 31 | 31 | Alamar | $1,170 | -25.1% | 4 | - | $292 | $13,710 | 4 | Benelux Film Distributors | false | false |
| 32 | 33 | Chicas | $987 | -35.1% | 3 | - | $329 | $5,651 | 3 | Benelux Film Distributors | false | false |
| 33 | 34 | Enter the Void | $954 | -35.4% | 4 | - | $238 | $7,231 | 3 | Cinéart | false | false |
| 34 | 38 | Agora | $870 | -12.2% | 3 | -1 | $290 | $166,949 | 15 | Benelux Film Distributors | false | false |
| 35 | 41 | The Ghost Writer | $776 | +802.3% | 2 | - | $388 | $863,505 | 19 | Benelux Film Distributors | false | false |
| 36 | 37 | The Last Station 2010 Re-release | $565 | -46.3% | 3 | - | $188 | $28,463 | 7 | Belga Films | false | false |
