| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Schuks Tshabalala's Survival Guide to South Africa | $469,215 | - | 110 | - | $4,265 | $469,215 | 1 | N/A | true | false |
| 2 | - | Sex and the City 2 | $273,380 | - | 71 | - | $3,850 | $273,380 | 1 | 20th Century Fox International | true | false |
| 3 | 1 | Prince of Persia: The Sands of Time | $210,347 | -26.6% | 93 | +1 | $2,261 | $632,945 | 2 | Walt Disney Pictures | false | false |
| 4 | 2 | Robin Hood | $102,312 | -31.5% | 73 | - | $1,401 | $671,730 | 3 | United International Pictures | false | false |
| 5 | 3 | Iron Man 2 | $100,502 | -25.2% | 78 | -1 | $1,288 | $2,011,748 | 5 | Paramount Pictures International | false | false |
| 6 | - | Green Zone 2010 Re-release | $69,115 | - | 45 | - | $1,535 | $69,115 | 1 | United International Pictures | true | false |
| 7 | - | Space Chimps 2: Zartog Strikes Back | $56,367 | - | 27 | - | $2,087 | $56,367 | 1 | United International Pictures | true | false |
| 8 | 4 | The Back-up Plan | $47,907 | -37.4% | 38 | -12 | $1,260 | $535,428 | 4 | Sony Pictures Releasing | false | false |
| 9 | 5 | The Last Song | $35,904 | -32.3% | 27 | -8 | $1,329 | $209,821 | 3 | Walt Disney Pictures | false | false |
| 10 | 6 | Kites | $18,646 | -46.6% | 12 | - | $1,553 | $63,593 | 2 | N/A | false | false |
| 11 | 11 | The Ghost Writer | $12,880 | -38.8% | 20 | - | $644 | $47,374 | 2 | NuMetro Distribution | false | false |
| 12 | 7 | I Now Pronounce You Black and White | $12,401 | -59.9% | 21 | -16 | $590 | $117,188 | 3 | N/A | false | false |
| 13 | 16 | A Serious Man | $12,107 | +22.5% | 8 | -2 | $1,513 | $45,116 | 3 | Ster-Kinekor Pictures | false | false |
| 14 | 9 | Hot Tub Time Machine | $11,787 | -47.5% | 30 | - | $392 | $49,034 | 2 | NuMetro Distribution | false | false |
| 15 | 8 | Jakhalsdans | $9,435 | -65.4% | 88 | +66 | $107 | $411,116 | 6 | N/A | false | false |
| 16 | - | The Last Station 2010 Re-release | $7,943 | - | 6 | - | $1,323 | $142,075 | 10 | Ster-Kinekor Pictures | false | false |
| 17 | 10 | Edge of Darkness | $7,505 | -64.4% | 16 | -24 | $469 | $239,495 | 4 | NuMetro Distribution | false | false |
| 18 | 13 | How to Train Your Dragon | $4,181 | -75.2% | 16 | -10 | $261 | $2,120,894 | 10 | United International Pictures | false | false |
| 19 | 19 | Love Happens | $3,474 | -44% | 6 | -7 | $579 | $184,451 | 5 | Ster-Kinekor Pictures | false | false |
| 20 | - | The Men Who Stare at Goats | $3,144 | - | 7 | - | $449 | $68,744 | 5 | NuMetro Distribution | false | false |
| 21 | 18 | Date Night | $3,033 | -62.2% | 7 | -11 | $433 | $804,514 | 8 | 20th Century Fox International | false | false |
| 22 | - | Seraphine | $2,789 | - | 3 | - | $929 | $20,067 | 4 | Ster-Kinekor Pictures | false | false |
| 23 | - | Paris 36 | $2,620 | - | 3 | - | $873 | $2,505 | 1 | Ster-Kinekor Pictures | true | false |
| 24 | 20 | Nanny McPhee Returns | $1,462 | -75.6% | 6 | -9 | $243 | $554,487 | 9 | United International Pictures | false | false |
| 25 | 22 | Shutter Island | $378 | +3% | 1 | - | $378 | $686,846 | 12 | United International Pictures | false | false |
| 26 | 21 | Leap Year | $357 | -87.4% | 4 | -7 | $89 | $287,113 | 7 | United International Pictures | false | false |
