| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Alice in Wonderland | $3,360,921 | -30.7% | 442 | -125 | $7,603 | $18,600,456 | 3 | Walt Disney Pictures | false | false |
| 2 | 1 | Iron Man 2 | $2,913,911 | -40.1% | 595 | -31 | $4,897 | $9,216,609 | 2 | Paramount Pictures International | false | false |
| 3 | - | A Nightmare on Elm Street | $552,543 | - | 154 | - | $3,587 | $552,543 | 1 | Warner Bros. | true | false |
| 4 | 3 | Chico Xavier | $529,116 | -45.2% | 335 | -5 | $1,579 | $15,990,245 | 6 | Sony Pictures Releasing | false | false |
| 5 | - | The Spy Next Door 2010 Re-release | $252,390 | - | 92 | - | $2,743 | $252,390 | 1 | N/A | true | false |
| 6 | 4 | The Bounty Hunter | $166,200 | -56.8% | 79 | -52 | $2,103 | $3,039,258 | 4 | Sony Pictures Releasing | false | false |
| 7 | 5 | Whatever Works | $161,769 | -28.3% | 30 | - | $5,392 | $525,489 | 2 | N/A | false | false |
| 8 | - | Dear John | $88,402 | - | 33 | - | $2,678 | $88,402 | 1 | Sony Pictures Releasing | true | false |
| 9 | 6 | Date Night | $83,580 | -61% | 90 | -54 | $928 | $3,696,489 | 5 | 20th Century Fox International | false | false |
| 10 | 7 | How to Train Your Dragon | $61,594 | -61.8% | 177 | -24 | $347 | $12,737,449 | 7 | Paramount Pictures International | false | false |
| 11 | - | Segurança Nacional | $58,510 | - | 37 | - | $1,581 | $58,510 | 1 | Europa Filmes | true | false |
| 12 | 8 | The Best Things in the World | $43,084 | -53.2% | 71 | -52 | $606 | $1,059,786 | 4 | Warner Bros. | false | false |
| 13 | 10 | The Secret in Their Eyes | $32,698 | -26.2% | 21 | -2 | $1,557 | $1,470,366 | 11 | Europa Filmes | false | false |
| 14 | - | The Imaginarium of Doctor Parnassus | $29,914 | - | 6 | - | $4,985 | $37,362 | 1 | Sony Pictures Releasing | true | false |
| 15 | 14 | Green Zone 2010 Re-release | $27,478 | +81.7% | 27 | +12 | $1,017 | $475,118 | 4 | Paramount Pictures International | false | false |
| 16 | 9 | The Road | $24,001 | -52.2% | 11 | -43 | $2,181 | $315,318 | 3 | Paris Filmes | false | false |
| 17 | 13 | Shutter Island | $11,906 | -42.1% | 17 | -9 | $700 | $4,811,221 | 9 | Paramount Pictures International | false | false |
| 18 | 12 | The Book of Eli | $7,738 | -62.8% | 30 | -35 | $257 | $4,458,053 | 8 | Sony Pictures Releasing | false | false |
| 19 | 18 | Did You Hear About the Morgans? | $6,733 | -16.7% | 8 | +2 | $841 | $587,783 | 7 | Sony Pictures Releasing | false | false |
| 20 | 11 | The Blind Side | $5,800 | -74.2% | 10 | -20 | $580 | $2,999,353 | 8 | Warner Bros. | false | false |
| 21 | 15 | From Paris with Love | $3,935 | -64.6% | 28 | -13 | $140 | $1,303,514 | 5 | PlayArte Pictures | false | false |
| 22 | 19 | Mary and Max | $3,933 | -46.1% | 8 | -2 | $491 | $100,809 | 4 | PlayArte Pictures | false | false |
| 23 | 16 | The Box | $2,477 | -77.4% | 12 | -4 | $206 | $503,834 | 7 | N/A | false | false |
| 24 | 17 | Stolen Dreams | $1,646 | -82.8% | 9 | -18 | $182 | $80,402 | 2 | Europa Filmes | false | false |
| 25 | 21 | Old Dogs | $1,169 | -75.8% | 7 | +2 | $167 | $597,804 | 6 | Walt Disney Pictures | false | false |
| 26 | 25 | The Men Who Stare at Goats | $965 | -54.5% | 2 | -2 | $482 | $129,683 | 7 | Sony Pictures Releasing | false | false |
| 27 | 22 | It's Complicated | $826 | -82.4% | 4 | -3 | $206 | $4,694,495 | 11 | Universal Pictures International (UPI) | false | false |
| 28 | 27 | The Hurt Locker | $757 | -50.5% | 8 | +2 | $94 | $820,754 | 14 | N/A | false | false |
| 29 | 20 | Case 39 | $529 | -90.7% | 4 | -10 | $132 | $1,044,893 | 5 | Paramount Pictures International | false | false |
| 30 | 30 | Easy Virtue | $486 | -21.5% | 2 | - | $243 | $201,042 | 29 | Sony Pictures Releasing | false | false |
| 31 | 23 | Percy Jackson & the Olympians: The Lightning Thief | $426 | -85.4% | 6 | -16 | $71 | $9,290,334 | 13 | 20th Century Fox International | false | false |
| 32 | 29 | An Education | $300 | -73.5% | 4 | - | $75 | $333,008 | 12 | Sony Pictures Releasing | false | false |
| 33 | 26 | Valentine's Day | $272 | -84.7% | 2 | -5 | $136 | $4,405,954 | 12 | Warner Bros. | false | false |
| 34 | 34 | Zombieland | $194 | -14.2% | 1 | - | $194 | $408,234 | 15 | Sony Pictures Releasing | false | false |
| 35 | 33 | The Princess and the Frog | $175 | -33.5% | 3 | +1 | $58 | $4,074,350 | 22 | Walt Disney Pictures | false | false |
| 36 | 35 | High School Musical: O Desafio | $114 | +119.2% | 2 | +1 | $57 | $1,143,027 | 14 | Walt Disney Pictures | false | false |
