| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Clash of the Titans | $73,710 | -28.5% | 9 | +1 | $8,190 | $211,927 | 2 | Warner Bros. | false | false |
| 2 | - | The Ghost Writer | $17,626 | - | 6 | - | $2,937 | $17,626 | 1 | Jaguar Film International Distribution | true | false |
| 3 | - | OceanWorld | $14,655 | - | 3 | - | $4,885 | $14,655 | 1 | Prime Pictures | true | false |
| 4 | 2 | The Bounty Hunter | $13,063 | -30.6% | 5 | -1 | $2,612 | $197,838 | 5 | Sony Pictures Releasing | false | false |
| 5 | - | Nanny McPhee Returns | $12,776 | - | 6 | - | $2,129 | $12,776 | 1 | United International Pictures | true | false |
| 6 | 7 | The Last Song | $10,897 | -13.8% | 5 | - | $2,179 | $77,381 | 4 | Walt Disney Pictures | false | false |
| 7 | 5 | Date Night | $10,188 | -21.5% | 5 | -2 | $2,037 | $54,303 | 3 | 20th Century Fox International | false | false |
| 8 | 4 | Remember Me | $9,872 | -27.9% | 5 | -1 | $1,974 | $80,194 | 4 | Jaguar Film International Distribution | false | false |
| 9 | 6 | How to Train Your Dragon | $7,133 | -44% | 5 | -2 | $1,426 | $126,010 | 5 | United International Pictures | false | false |
| 10 | - | Captain Alatriste: The Spanish Musketeer 2010 Re-release | $6,974 | - | 5 | - | $1,394 | $6,974 | 1 | Italian International Film | true | false |
| 11 | 3 | Alice in Wonderland | $6,329 | -58.5% | 6 | - | $1,054 | $426,763 | 8 | Walt Disney Pictures | false | false |
| 12 | 8 | Green Zone | $3,889 | -58% | 3 | -3 | $1,296 | $156,274 | 6 | United International Pictures | false | false |
| 13 | 9 | The Hurt Locker | $3,466 | -41.8% | 2 | -1 | $1,733 | $25,490 | 3 | N/A | false | false |
| 14 | 23 | Siraj El Wadi | $2,699 | +2,520.4% | 1 | - | $2,699 | $75,485 | 25 | Italian International Film | false | false |
| 15 | 13 | Dorian Gray | $2,673 | -36.9% | 1 | - | $2,673 | $28,522 | 4 | Prime Pictures | false | false |
| 16 | 15 | My Name Is Khan | $1,439 | -43.5% | 2 | -1 | $719 | $56,764 | 7 | 20th Century Fox International | false | false |
| 17 | 11 | Shutter Island | $1,254 | -71.8% | 2 | -1 | $627 | $164,315 | 7 | United International Pictures | false | false |
| 18 | 10 | Tooth Fairy | $1,245 | -77.4% | 3 | -3 | $415 | $43,369 | 4 | 20th Century Fox International | false | false |
| 19 | 17 | Dear John | $1,212 | +16.8% | 1 | - | $1,212 | $41,168 | 5 | N/A | false | false |
| 20 | 16 | Arthur and the Revenge of Maltazard | $1,085 | -45.6% | 4 | -1 | $271 | $17,002 | 4 | Walt Disney Pictures | false | false |
| 21 | 18 | When in Rome | $888 | -9.1% | 3 | -1 | $296 | $111,225 | 9 | Walt Disney Pictures | false | false |
| 22 | 19 | The Spy Next Door 2010 Re-release | $811 | -14.1% | 1 | - | $811 | $48,095 | 7 | N/A | false | false |
| 23 | 20 | From Paris with Love | $785 | +26% | 3 | - | $261 | $176,457 | 10 | Italian International Film | false | false |
| 24 | - | Everybody's Fine | $694 | - | 1 | - | $694 | $54,799 | 13 | Walt Disney Pictures | false | false |
| 25 | 22 | Agora | $215 | -45.7% | 1 | -1 | $215 | $133,622 | 17 | Italian International Film | false | false |
| 26 | - | Cold Souls | $133 | - | 1 | - | $133 | $133 | 1 | N/A | true | false |
| 27 | 21 | The Burning Plain | $133 | -74.5% | 1 | -1 | $133 | $16,202 | 6 | N/A | false | false |
