| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Clash of the Titans | $357,418 | -50% | 92 | -11 | $3,884 | $1,243,644 | 2 | Warner Bros. | false | false |
| 2 | 2 | How to Train Your Dragon | $108,539 | -13.5% | 52 | - | $2,087 | $1,282,845 | 5 | United International Pictures | false | false |
| 3 | 3 | Shutter Island | $89,830 | -25.6% | 32 | -2 | $2,807 | $495,679 | 3 | United International Pictures | false | false |
| 4 | - | The Bounty Hunter | $48,605 | - | 22 | - | $2,209 | $48,605 | 1 | Sony Pictures Releasing | true | false |
| 5 | - | Remember Me | $32,990 | - | 16 | - | $2,061 | $32,990 | 1 | N/A | true | false |
| 6 | - | The Girl with the Dragon Tattoo | $29,255 | - | 12 | - | $2,437 | $29,255 | 1 | Andes Films | true | false |
| 7 | 5 | The Young Victoria | $17,373 | -17.6% | 8 | - | $2,171 | $44,834 | 2 | N/A | false | false |
| 8 | - | Law Abiding Citizen | $17,028 | - | 19 | - | $896 | $17,028 | 1 | Transeuropa | true | false |
| 9 | 7 | The Secret in Their Eyes | $9,993 | -12.6% | 3 | - | $3,331 | $435,752 | 16 | N/A | false | false |
| 10 | 4 | Legion | $9,870 | -66.6% | 19 | -7 | $519 | $436,401 | 5 | Sony Pictures Releasing | false | false |
| 11 | 6 | Edge of Darkness | $8,622 | -58.9% | 13 | -15 | $663 | $178,383 | 4 | Warner Bros. | false | false |
| 12 | 10 | The Haunting in Connecticut | $3,256 | -41.9% | 6 | +3 | $542 | $209,713 | 15 | Transeuropa | false | false |
| 13 | 9 | Let the Right One In | $3,117 | -49.9% | 5 | - | $623 | $209,713 | 5 | N/A | false | false |
| 14 | 17 | Avatar | $2,797 | -11% | 13 | -1 | $215 | $10,401,569 | 19 | 20th Century Fox International | false | false |
| 15 | 8 | 500 Days of Summer | $2,745 | -57.4% | 4 | -1 | $686 | $129,643 | 7 | 20th Century Fox International | false | false |
| 16 | 16 | The Men Who Stare at Goats | $2,606 | -21.2% | 8 | +4 | $325 | $39,899 | 4 | Sony Pictures Releasing | false | false |
| 17 | 19 | Alvin and the Chipmunks: The Squeakquel | $1,274 | -35.8% | 3 | -2 | $424 | $1,411,629 | 13 | 20th Century Fox International | false | false |
| 18 | 15 | Percy Jackson & the Olympians: The Lightning Thief | $965 | -70.9% | 3 | -5 | $321 | $796,602 | 11 | 20th Century Fox International | false | false |
| 19 | 18 | [Rec]² | $911 | -61.8% | 5 | -3 | $182 | $96,032 | 6 | N/A | false | false |
| 20 | 14 | The Hurt Locker | $858 | -74.5% | 1 | -5 | $858 | $348,664 | 10 | N/A | false | false |
| 21 | 21 | Amelia | $789 | -32.1% | 5 | - | $157 | $10,020 | 3 | 20th Century Fox International | false | false |
| 22 | 11 | My Life in Ruins | $443 | -91.9% | 4 | -7 | $110 | $25,380 | 3 | N/A | false | false |
| 23 | 13 | Daybreakers | $379 | -89.9% | 4 | -7 | $94 | $57,061 | 4 | N/A | false | false |
| 24 | 12 | The Blind Side | $290 | -94% | 1 | -3 | $290 | $95,126 | 6 | Warner Bros. | false | false |
| 25 | 24 | Halloween II | $123 | -64.1% | 1 | -1 | $123 | $63,966 | 7 | N/A | false | false |
| 26 | 22 | The Burning Plain | $77 | -92.1% | 1 | -1 | $77 | $7,800 | 3 | N/A | false | false |
