| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Alice in Wonderland | $55,700 | +3.6% | 4 | - | $13,925 | $278,725 | 4 | Walt Disney Pictures | false | false |
| 2 | - | The Bounty Hunter | $46,908 | - | 6 | - | $7,818 | $46,908 | 1 | Sony Pictures Releasing | true | false |
| 3 | 4 | My Name Is Khan | $37,030 | +2.2% | 8 | - | $4,628 | $277,885 | 6 | 20th Century Fox International | false | false |
| 4 | 3 | Shutter Island | $32,018 | -19.5% | 10 | - | $3,201 | $147,724 | 3 | United International Pictures | false | false |
| 5 | 5 | Avatar | $30,328 | -10.9% | 7 | - | $4,332 | $2,192,348 | 15 | 20th Century Fox International | false | false |
| 6 | 2 | Green Zone | $25,524 | -39% | 10 | - | $2,552 | $70,987 | 2 | United International Pictures | false | false |
| 7 | 6 | From Paris with Love | $23,213 | -22.9% | 10 | - | $2,321 | $102,409 | 3 | N/A | false | false |
| 8 | 9 | The Wolfman | $11,607 | +12% | 9 | - | $1,289 | $134,677 | 5 | United International Pictures | false | false |
| 9 | - | The Lovely Bones | $10,170 | - | 8 | - | $1,271 | $10,170 | 1 | United International Pictures | true | false |
| 10 | 8 | Valentine's Day | $9,021 | -23.9% | 4 | -1 | $2,255 | $242,884 | 7 | Warner Bros. | false | false |
| 11 | 7 | When in Rome | $7,370 | -55.5% | 4 | - | $1,842 | $26,842 | 2 | Walt Disney Pictures | false | false |
| 12 | 10 | The Children | $7,219 | +1.7% | 4 | - | $1,804 | $25,241 | 3 | - | false | false |
| 13 | 11 | It's Complicated | $4,490 | -7.1% | 5 | - | $898 | $119,776 | 8 | United International Pictures | false | false |
| 14 | 12 | The Book of Eli | $3,800 | -20.7% | 4 | -2 | $950 | $260,605 | 9 | - | false | false |
| 15 | 13 | Up in the Air | $3,336 | -10.1% | 5 | - | $667 | $75,299 | 7 | United International Pictures | false | false |
| 16 | 14 | Percy Jackson & the Olympians: The Lightning Thief | $2,789 | -20.8% | 3 | - | $929 | $106,298 | 7 | 20th Century Fox International | false | false |
| 17 | 16 | Stag Night | $1,312 | -33.2% | 1 | -1 | $1,312 | $31,117 | 5 | N/A | false | false |
| 18 | 19 | Alvin and the Chipmunks: The Squeakquel | $494 | -3.5% | 1 | -1 | $494 | $150,452 | 14 | 20th Century Fox International | false | false |
| 19 | 18 | The Tournament | $379 | -58.1% | 1 | - | $379 | $17,651 | 4 | - | false | false |
| 20 | 15 | Sherlock Holmes | $300 | -89.3% | 1 | -1 | $300 | $397,144 | 13 | Warner Bros. | false | false |
| 21 | 21 | Old Dogs | $293 | +57.5% | 1 | - | $293 | $124,036 | 12 | Walt Disney Pictures | false | false |
| 22 | 17 | The Princess and the Frog | $222 | -81% | 2 | -1 | $111 | $78,687 | 13 | Walt Disney Pictures | false | false |
| 23 | 20 | 2012 | $221 | -28.7% | 1 | - | $221 | $1,100,706 | 20 | Sony Pictures Releasing | false | false |
| 24 | 25 | Did You Hear About the Morgans? | $38 | -19.1% | 1 | - | $38 | $61,799 | 9 | Sony Pictures Releasing | false | false |
