| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Alice in Wonderland | $436,067 | -35.6% | 18 | - | $24,225 | $1,713,120 | 2 | Walt Disney Pictures | false | false |
| 2 | - | Green Zone | $158,347 | - | 17 | - | $9,314 | $205,758 | 1 | United International Pictures | true | false |
| 3 | - | The Hurt Locker | $125,453 | - | 13 | - | $9,650 | $160,330 | 1 | N/A | true | false |
| 4 | - | Did You Hear About the Morgans? | $74,467 | - | 27 | - | $2,758 | $91,228 | 1 | Sony Pictures Releasing | true | false |
| 5 | 2 | Shutter Island | $53,664 | -60.1% | 15 | -1 | $3,577 | $742,757 | 3 | United International Pictures | false | false |
| 6 | 5 | The Blind Side | $53,146 | -12.7% | 13 | - | $4,088 | $359,188 | 3 | Warner Bros. | false | false |
| 7 | 3 | Up in the Air | $37,712 | -52.9% | 16 | - | $2,357 | $190,077 | 2 | United International Pictures | false | false |
| 8 | 4 | Nodame Cantabile: The Movie II | $31,669 | -49.3% | 11 | - | $2,879 | $141,867 | 2 | N/A | false | false |
| 9 | 6 | Avatar | $22,543 | -38.1% | 6 | -3 | $3,757 | $13,441,856 | 13 | 20th Century Fox International | false | false |
| 10 | - | Brothers | $10,701 | - | 9 | - | $1,189 | $13,722 | 1 | N/A | true | false |
| 11 | 7 | Nine | $8,622 | -73.3% | 6 | -7 | $1,437 | $220,501 | 3 | N/A | false | false |
| 12 | 8 | Monga | $6,841 | -73.2% | 9 | -7 | $760 | $3,646,304 | 6 | Warner Bros. | false | false |
| 13 | - | A Prophet | $3,635 | - | 4 | - | $908 | $4,443 | 1 | N/A | true | false |
| 14 | 9 | Percy Jackson & the Olympians: The Lightning Thief | $2,606 | -86.5% | 3 | -10 | $868 | $1,180,488 | 5 | 20th Century Fox International | false | false |
| 15 | 11 | A Single Man | $1,399 | -84.4% | 3 | -4 | $466 | $20,234 | 2 | N/A | false | false |
| 16 | 12 | Valentine's Day | $474 | -88.6% | 1 | -3 | $474 | $560,927 | 5 | Warner Bros. | false | false |
| 17 | 13 | The Road | $116 | -96.8% | 1 | -4 | $116 | $34,774 | 3 | N/A | false | false |
| 18 | 20 | Villon's Wife | $44 | +37.5% | 1 | - | $44 | $19,879 | 5 | N/A | false | false |
