| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Shutter Island | $555,576 | -25.5% | 46 | - | $12,077 | $1,500,348 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | Avatar | $299,130 | -22.8% | 119 | -14 | $2,513 | $14,151,240 | 12 | 20th Century Fox International | false | false |
| 3 | 3 | The Princess and the Frog | $173,358 | -39.3% | 65 | - | $2,667 | $3,081,686 | 5 | Walt Disney Pictures | false | false |
| 4 | 4 | Percy Jackson & the Olympians: The Lightning Thief | $157,118 | -33.2% | 80 | - | $1,963 | $1,866,642 | 4 | 20th Century Fox International | false | false |
| 5 | 6 | Bo | $139,298 | -24.2% | 23 | - | $6,056 | $1,154,680 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 6 | 5 | Valentine's Day | $130,965 | -39.1% | 48 | - | $2,728 | $1,437,108 | 4 | 20th Century Fox International | false | false |
| 7 | 7 | The Pimp | $115,341 | -25.8% | 18 | - | $6,407 | $556,573 | 3 | Belga Films | false | false |
| 8 | 8 | From Paris with Love | $95,652 | -37.5% | 33 | - | $2,898 | $271,414 | 2 | Belga Films | false | false |
| 9 | - | Nine | $80,136 | - | 30 | - | $2,671 | $121,161 | 1 | Paradiso Entertainment | true | false |
| 10 | 9 | Edge of Darkness | $73,845 | -36.7% | 39 | -4 | $1,893 | $545,850 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 11 | 12 | A Single Man | $72,016 | -17.6% | 11 | - | $6,546 | $184,103 | 2 | Cinéart | false | false |
| 12 | - | Precious | $66,116 | - | 16 | - | $4,132 | $71,669 | 1 | A-Film Distribution | true | false |
| 13 | 11 | Planet 51 | $62,780 | -32.1% | 59 | -1 | $1,064 | $748,050 | 4 | Belga Films | false | false |
| 14 | - | Coursier | $60,627 | - | 16 | - | $3,789 | $60,627 | 1 | Belga Films | true | false |
| 15 | 10 | The Wolfman | $59,288 | -46.1% | 36 | - | $1,646 | $1,017,488 | 4 | Universal Pictures International (UPI) | false | false |
| 16 | 13 | Alvin and the Chipmunks: The Squeakquel | $44,804 | -35.7% | 42 | -6 | $1,066 | $4,336,228 | 11 | 20th Century Fox International | false | false |
| 17 | 14 | I Love You Phillip Morris | $40,067 | -37.3% | 24 | -3 | $1,669 | $325,698 | 3 | Belga Films | false | false |
| 18 | 17 | Oceans | $29,287 | -33.8% | 26 | +1 | $1,126 | $669,044 | 6 | Alternative Films | false | false |
| 19 | 20 | The Imaginarium of Doctor Parnassus | $25,424 | -29.4% | 16 | +2 | $1,589 | $347,866 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 20 | 15 | Cloudy with a Chance of Meatballs | $23,717 | -57% | 27 | -3 | $878 | $1,059,580 | 8 | Sony Pictures Releasing | false | false |
| 21 | 18 | Sherlock Holmes | $23,125 | -43% | 22 | -2 | $1,051 | $2,733,528 | 9 | Warner Bros. | false | false |
| 22 | 19 | Dossier K. | $22,701 | -37.2% | 12 | -3 | $1,891 | $3,647,774 | 13 | Kinepolis Film Distribution (KFD) | false | false |
| 23 | 16 | The Lovely Bones | $22,689 | -51.7% | 21 | -5 | $1,080 | $482,792 | 4 | Universal Pictures International (UPI) | false | false |
| 24 | 23 | An Education | $21,377 | -28.1% | 8 | - | $2,672 | $65,234 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 25 | 21 | Up in the Air | $17,789 | -49.2% | 11 | -5 | $1,617 | $1,090,292 | 7 | Universal Pictures International (UPI) | false | false |
| 26 | - | Together Is Too Much | $16,928 | - | 8 | - | $2,116 | $36,116 | 1 | Cinéart | true | false |
| 27 | 24 | A Serious Man | $16,885 | -38.6% | 13 | +1 | $1,298 | $452,688 | 7 | Universal Pictures International (UPI) | false | false |
| 28 | 25 | Invictus | $16,069 | -23.2% | 12 | -2 | $1,339 | $729,867 | 8 | Warner Bros. | false | false |
| 29 | 22 | Gainsbourg: A Heroic Life | $15,275 | -52.4% | 16 | -5 | $954 | $439,946 | 5 | Cinéart | false | false |
| 30 | - | Crazy Heart | $13,852 | - | 5 | - | $2,770 | $14,018 | 1 | 20th Century Fox International | true | false |
| 31 | 27 | Mr. Nobody | $11,191 | -31.9% | 15 | +2 | $746 | $807,056 | 8 | Belga Films | false | false |
| 32 | 26 | The Book of Eli | $10,931 | -45.7% | 11 | -7 | $993 | $555,003 | 5 | Paradiso Entertainment | false | false |
| 33 | 30 | Fantastic Mr. Fox | $9,878 | -20.6% | 17 | - | $581 | $67,849 | 3 | 20th Century Fox International | false | false |
| 34 | 29 | Vincere | $8,950 | -28.9% | 7 | -1 | $1,278 | $82,225 | 4 | ABC Distribution | false | false |
| 35 | - | Thelma, Louise et Chantal | $8,211 | - | 4 | - | $2,052 | $9,529 | 1 | Les Films de l'Elysée | true | false |
| 36 | 35 | The Concert | $6,295 | +36.6% | 11 | -1 | $572 | $817,027 | 17 | Cinéart | false | false |
| 37 | 32 | Did You Hear About the Morgans? | $4,948 | -46.6% | 9 | -5 | $549 | $756,459 | 6 | Sony Pictures Releasing | false | false |
| 38 | - | Tales from the Golden Age 2009 Re-release | $3,873 | - | 4 | - | $968 | $5,176 | 1 | N/A | true | false |
| 39 | 38 | The Girl Who Played with Fire | $3,306 | -5.7% | 7 | - | $472 | $191,212 | 8 | Benelux Film Distributors | false | false |
| 40 | 28 | The Boat Race | $3,142 | -75.4% | 5 | -1 | $628 | $23,734 | 2 | Cinéart | false | false |
| 41 | 37 | The Road | $2,745 | -30.2% | 13 | - | $211 | $359,515 | 6 | Benelux Film Distributors | false | false |
| 42 | 36 | Mary and Max | $2,542 | -40.2% | 3 | - | $847 | $8,277 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 43 | 40 | Silent Voice | $2,252 | -28.3% | 4 | - | $563 | $17,677 | 3 | Cinéart | false | false |
| 44 | 34 | OceanWorld | $2,237 | -56.4% | 7 | - | $319 | $71,727 | 4 | N/A | false | false |
| 45 | 44 | No One Knows About Persian Cats | $1,736 | -33.6% | 3 | - | $578 | $52,305 | 6 | Cinéart | false | false |
| 46 | 43 | The Barons | $1,706 | -37.7% | 8 | -1 | $213 | $1,266,035 | 18 | Cinéart | false | false |
| 47 | 49 | Katalin Varga | $473 | -50.7% | 1 | - | $473 | $1,622 | 2 | Benelux Film Distributors | false | false |
| 48 | - | Persécution | $454 | - | 2 | - | $227 | $454 | 1 | N/A | true | false |
| 49 | - | The Indian | $77 | - | 1 | - | $77 | $77 | 1 | Jekino | true | false |
