| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Shutter Island | $1,072,830 | - | 65 | - | $16,505 | $1,072,830 | 1 | United International Pictures | true | false |
| 2 | 1 | Percy Jackson & the Olympians: The Lightning Thief | $417,384 | -46.7% | 73 | +2 | $5,717 | $1,438,713 | 2 | 20th Century Fox International | false | false |
| 3 | 2 | The Princess and the Frog | $216,376 | -32.1% | 67 | +2 | $3,229 | $1,080,310 | 3 | Walt Disney Pictures | false | false |
| 4 | 4 | The Wolfman | $139,990 | -52.3% | 41 | - | $3,414 | $1,348,818 | 3 | United International Pictures | false | false |
| 5 | 3 | Edge of Darkness | $139,569 | -53% | 58 | -4 | $2,406 | $559,809 | 2 | Roadshow Films | false | false |
| 6 | 7 | Avatar | $121,824 | -26.6% | 19 | -3 | $6,411 | $10,824,094 | 11 | 20th Century Fox International | false | false |
| 7 | 5 | Up in the Air | $98,572 | -47.4% | 37 | - | $2,664 | $1,516,626 | 4 | United International Pictures | false | false |
| 8 | 9 | A Single Man | $55,387 | -41.3% | 8 | +1 | $6,923 | $185,789 | 2 | Roadshow Films | false | false |
| 9 | 8 | Valentine's Day | $54,740 | -64.7% | 24 | -16 | $2,280 | $759,802 | 3 | Warner Bros. | false | false |
| 10 | 6 | Cloudy with a Chance of Meatballs | $53,852 | -71.1% | 27 | -33 | $1,994 | $413,728 | 5 | Sony Pictures Releasing | false | false |
