| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $405,720 | -23.3% | 112 | -5 | $3,622 | $12,835,979 | 9 | 20th Century Fox International | false | false |
| 2 | - | Edge of Darkness | $288,310 | - | 57 | - | $5,058 | $288,310 | 1 | Warner Bros. | true | false |
| 3 | 2 | Percy Jackson & the Olympians: The Lightning Thief | $141,967 | -42% | 65 | +1 | $2,184 | $499,223 | 2 | 20th Century Fox International | false | false |
| 4 | 4 | Toy Story 2 2009 Re-release | $128,976 | -31.7% | 30 | +1 | $4,299 | $418,777 | 2 | Walt Disney Pictures | false | false |
| 5 | 3 | The Wolfman | $111,283 | -45.2% | 67 | +2 | $1,660 | $867,178 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | - | The Imaginarium of Doctor Parnassus | $90,605 | - | 30 | - | $3,020 | $90,605 | 1 | Sony Pictures Releasing | true | false |
| 7 | 5 | Valentine's Day | $73,919 | -54.3% | 65 | -2 | $1,137 | $758,551 | 3 | Warner Bros. | false | false |
| 8 | 6 | Old Dogs | $57,862 | -41.1% | 67 | - | $863 | $1,434,910 | 6 | Walt Disney Pictures | false | false |
| 9 | - | A Serious Man | $53,690 | - | 15 | - | $3,579 | $53,690 | 1 | Universal Pictures International (UPI) | true | false |
| 10 | 11 | Birds of Paradise | $46,606 | -32.6% | 41 | - | $1,136 | $151,650 | 2 | Sony Pictures Releasing | false | false |
| 11 | 9 | The Girl with the Dragon Tattoo | $45,816 | -48.6% | 22 | -1 | $2,082 | $162,661 | 2 | N/A | false | false |
| 12 | 10 | Invictus | $43,324 | -43.9% | 50 | -2 | $866 | $842,041 | 5 | Warner Bros. | false | false |
| 13 | 8 | Sherlock Holmes | $39,091 | -57.5% | 79 | -11 | $494 | $2,668,578 | 7 | Warner Bros. | false | false |
| 14 | 7 | The Lovely Bones | $36,678 | -61% | 57 | +3 | $643 | $169,892 | 2 | Paramount Pictures International | false | false |
| 15 | 13 | Tooth Fairy | $23,957 | -50% | 52 | -2 | $460 | $457,900 | 4 | 20th Century Fox International | false | false |
| 16 | 12 | Alvin and the Chipmunks: The Squeakquel | $22,828 | -52.8% | 71 | -16 | $321 | $1,069,035 | 6 | 20th Century Fox International | false | false |
| 17 | 15 | Precious | $20,138 | -51.5% | 31 | +5 | $649 | $182,857 | 3 | N/A | false | false |
| 18 | 20 | An Education | $11,546 | -17.7% | 10 | +4 | $1,154 | $169,372 | 4 | Sony Pictures Releasing | false | false |
| 19 | 18 | Up in the Air | $10,546 | -57.1% | 49 | +8 | $215 | $706,680 | 6 | Paramount Pictures International | false | false |
| 20 | 19 | The Princess and the Frog | $10,168 | -58% | 40 | -4 | $254 | $1,923,251 | 8 | Walt Disney Pictures | false | false |
| 21 | 17 | It's Complicated | $9,150 | -63.6% | 34 | -7 | $269 | $1,297,895 | 8 | Universal Pictures International (UPI) | false | false |
| 22 | 16 | Law Abiding Citizen | $7,366 | -81.3% | 26 | -16 | $283 | $175,439 | 3 | Alfa Films | false | false |
| 23 | 30 | Zombieland | $6,656 | +563.6% | 8 | +5 | $832 | $97,968 | 5 | Sony Pictures Releasing | false | false |
| 24 | 21 | The Wedding Song | $5,876 | -56.4% | 6 | +1 | $979 | $22,418 | 2 | Primer Plano Film Group | false | false |
| 25 | 27 | The Young Victoria | $3,863 | +133.1% | 13 | +3 | $297 | $175,780 | 7 | Distribution Company | false | false |
| 26 | - | Easy Virtue | $3,396 | - | 3 | - | $1,132 | $99,396 | 7 | Sony Pictures Releasing | false | false |
| 27 | 23 | The Secret in Their Eyes | $2,836 | -50.7% | 15 | - | $189 | $9,234,235 | 29 | Distribution Company | false | false |
| 28 | 25 | Nine | $2,446 | -43.5% | 7 | +2 | $349 | $259,883 | 5 | Sony Pictures Releasing | false | false |
| 29 | 26 | Nora's Will | $2,282 | +16.5% | 3 | - | $760 | $47,707 | 5 | Primer Plano Film Group | false | false |
| 30 | 29 | Ninja Assassin | $2,249 | +98.7% | 12 | +6 | $187 | $128,680 | 8 | Warner Bros. | false | false |
| 31 | 22 | Astro Boy | $1,546 | -77.5% | 23 | -3 | $67 | $153,006 | 5 | Alfa Films | false | false |
| 32 | 24 | Daybreakers | $878 | -83.9% | 4 | -10 | $219 | $377,049 | 6 | Distribution Company | false | false |
| 33 | 28 | 2012 | $560 | -61.1% | 1 | -1 | $560 | $4,038,916 | 13 | Sony Pictures Releasing | false | false |
| 34 | 31 | Le code a changé | $388 | -55.1% | 3 | - | $129 | $135,795 | 9 | Alfa Films | false | false |
| 35 | 35 | Andres Doesn't Want to Take a Nap | $371 | -11.9% | 2 | -1 | $185 | $11,303 | 4 | Primer Plano Film Group | false | false |
| 36 | 33 | The Wind Journeys | $271 | -62.2% | 2 | - | $135 | $3,936 | 3 | Primer Plano Film Group | false | false |
| 37 | 37 | Let it Rain | $177 | -24.4% | 1 | - | $177 | $140,017 | 12 | Alfa Films | false | false |
| 38 | - | Halloween II | $155 | - | 1 | - | $155 | $119,642 | 8 | Distribution Company | false | false |
| 39 | 42 | Inglourious Basterds | $73 | -41.6% | 1 | - | $73 | $1,224,853 | 26 | Universal Pictures International (UPI) | false | false |
| 40 | 41 | Broken Embraces | $57 | -57.8% | 1 | - | $57 | $520,451 | 22 | Universal Pictures International (UPI) | false | false |
| 41 | 34 | Departures | $31 | -93.6% | 1 | -1 | $31 | $19,852 | 7 | Alfa Films | false | false |
| 42 | 32 | Paranormal Activity | $21 | -97.4% | 3 | - | $7 | $1,272,176 | 12 | Distribution Company | false | false |
| 43 | 40 | The Twilight Saga: New Moon | $21 | -84.4% | 1 | -2 | $21 | $3,302,766 | 15 | Alfa Films | false | false |
