| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | The Princess and the Frog | $4,918,893 | +10.2% | 700 | +3 | $7,026 | $25,207,038 | 4 | Walt Disney Pictures | false | false |
| 2 | - | Valentine's Day | $4,784,524 | - | 408 | - | $11,726 | $4,784,524 | 1 | Warner Bros. | true | false |
| 3 | 1 | Avatar | $4,596,717 | -5.6% | 529 | -51 | $8,689 | $152,714,341 | 10 | 20th Century Fox International | false | false |
| 4 | - | The Pimp | $4,454,916 | - | 465 | - | $9,580 | $4,454,916 | 1 | N/A | true | false |
| 5 | 3 | Sherlock Holmes | $2,810,284 | -25.7% | 667 | -3 | $4,213 | $14,683,858 | 3 | Warner Bros. | false | false |
| 6 | 5 | Oceans | $2,592,055 | -13.6% | 581 | +3 | $4,461 | $19,026,472 | 4 | N/A | false | false |
| 7 | 4 | Percy Jackson & the Olympians: The Lightning Thief | $2,556,096 | -24.6% | 555 | +23 | $4,605 | $6,897,253 | 2 | 20th Century Fox International | false | false |
| 8 | 8 | Planet 51 | $1,607,823 | +13.8% | 459 | -10 | $3,502 | $5,663,091 | 3 | N/A | false | false |
| 9 | - | Edge of Darkness | $1,567,346 | - | 357 | - | $4,390 | $1,567,346 | 1 | Metropolitan Filmexport | true | false |
| 10 | - | From Paris with Love | $1,479,358 | - | 437 | - | $3,385 | $1,479,358 | 1 | Europa Filmes | true | false |
| 11 | - | Together Is Too Much | $1,329,141 | - | 271 | - | $4,904 | $1,329,141 | 1 | StudioCanal | true | false |
| 12 | 6 | Invictus | $1,318,520 | -26% | 440 | -46 | $2,996 | $24,666,808 | 6 | Warner Bros. | false | false |
| 13 | - | Fantastic Mr. Fox | $863,825 | - | 147 | - | $5,876 | $863,825 | 1 | 20th Century Fox International | true | false |
| 14 | 9 | I Love You Phillip Morris | $763,150 | -40.9% | 198 | - | $3,854 | $2,395,467 | 2 | Europa Filmes | false | false |
| 15 | 7 | The Wolfman | $679,625 | -56.6% | 359 | -12 | $1,893 | $2,621,927 | 2 | Universal Pictures International (UPI) | false | false |
| 16 | 10 | The Lovely Bones | $580,145 | -54% | 285 | -16 | $2,035 | $2,174,440 | 2 | Paramount Pictures International | false | false |
| 17 | 13 | Up in the Air | $421,978 | -46.3% | 145 | -106 | $2,910 | $6,303,497 | 4 | Paramount Pictures International | false | false |
| 18 | 12 | Dumas | $349,628 | -59.9% | 233 | -48 | $1,500 | $1,465,639 | 2 | UGC Distribution | false | false |
| 19 | 11 | Protéger & servir | $319,629 | -69.2% | 221 | -120 | $1,446 | $3,705,893 | 3 | N/A | false | false |
| 20 | 14 | Brothers | $306,988 | -54.3% | 121 | -63 | $2,537 | $2,538,466 | 3 | Wild Bunch Distribution | false | false |
| 21 | - | The Boat Race | $91,809 | - | 39 | - | $2,354 | $91,809 | 1 | Pyramide Distribution | true | false |
| 22 | - | Tatarak | $47,395 | - | 20 | - | $2,369 | $47,395 | 1 | N/A | true | false |
| 23 | 21 | Did You Hear About the Morgans? | $17,341 | -63.4% | 33 | -29 | $525 | $3,995,986 | 5 | Sony Pictures Releasing | false | false |
