| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Valentine's Day | $2,501,582 | -62.5% | 373 | - | $6,706 | $10,799,874 | 2 | Warner Bros. | false | false |
| 2 | - | Shutter Island | $2,499,967 | - | 250 | - | $9,999 | $2,499,967 | 1 | Paramount Pictures International | true | false |
| 3 | 2 | Avatar | $1,685,627 | -33.4% | 254 | -30 | $6,636 | $94,848,215 | 10 | 20th Century Fox International | false | false |
| 4 | 4 | Percy Jackson & the Olympians: The Lightning Thief | $967,308 | -33.6% | 229 | - | $4,224 | $2,751,782 | 2 | 20th Century Fox International | false | false |
| 5 | 3 | The Wolfman | $658,897 | -60.3% | 246 | +1 | $2,678 | $2,826,788 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | - | From Paris with Love | $487,605 | - | 153 | - | $3,186 | $487,605 | 1 | Hoyts Distribution | true | false |
| 7 | - | The Blind Side | $308,639 | - | 181 | - | $1,705 | $313,707 | - | Roadshow Films | - | false |
| 8 | - | The Hurt Locker | $276,011 | - | 46 | - | $6,000 | $354,438 | 1 | Roadshow Films | true | false |
| 9 | 11 | It's Complicated | $263,763 | -28.5% | 150 | -57 | $1,758 | $13,736,264 | 7 | Universal Pictures International (UPI) | false | false |
| 10 | 7 | Up in the Air | $261,932 | -39.3% | 123 | -35 | $2,129 | $6,724,065 | 6 | Paramount Pictures International | false | false |
| 11 | 5 | Edge of Darkness | $224,124 | -65.4% | 195 | -7 | $1,149 | $2,841,507 | 3 | Icon Film Distribution | false | false |
| 12 | - | Crazy Heart | $199,782 | - | 56 | - | $3,567 | $199,782 | 1 | 20th Century Fox International | true | false |
| 13 | 6 | Invictus | $176,265 | -60.1% | 124 | -100 | $1,421 | $5,940,076 | 5 | Warner Bros. | false | false |
| 14 | 8 | Law Abiding Citizen | $169,757 | -60.1% | 121 | -57 | $1,402 | $4,182,046 | 4 | Roadshow Films | false | false |
| 15 | 10 | My Name Is Khan | $156,362 | -59.8% | 37 | - | $4,226 | $685,888 | 2 | 20th Century Fox International | false | false |
| 16 | 12 | Bran Nue Dae | $155,723 | -32.5% | 113 | -62 | $1,378 | $6,148,468 | 6 | Roadshow Films | false | false |
| 17 | 9 | Daybreakers | $153,260 | -63.2% | 124 | -10 | $1,235 | $1,980,311 | 3 | Hoyts Distribution | false | false |
| 18 | - | Celine: Through the Eyes of the World | $119,274 | - | 45 | - | $2,650 | $119,274 | 1 | Sony Pictures Releasing | true | false |
| 19 | 14 | Precious | $119,160 | -28.6% | 30 | +2 | $3,972 | $712,988 | 3 | Icon Film Distribution | false | false |
| 20 | 13 | Tooth Fairy | $104,043 | -53.5% | 111 | -58 | $937 | $9,230,372 | 6 | 20th Century Fox International | false | false |
| 21 | - | The Ultimate Wave Tahiti | $22,390 | - | 2 | - | $11,195 | $22,390 | 1 | IMAX | true | false |
| 22 | - | North Face | $3,913 | - | 2 | - | $1,956 | $3,913 | 1 | Rialto Distribution | true | false |
