| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Wolfman | $548,677 | - | 45 | - | $12,192 | $548,677 | 1 | United International Pictures | true | false |
| 2 | - | The Princess and the Frog | $379,726 | - | 65 | - | $5,841 | $379,726 | 1 | Walt Disney Pictures | true | false |
| 3 | 1 | Up in the Air | $374,258 | -23.9% | 41 | -2 | $9,128 | $1,040,587 | 2 | United International Pictures | false | false |
| 4 | - | Valentine's Day | $359,183 | - | 45 | - | $7,981 | $359,183 | 1 | Warner Bros. | true | false |
| 5 | 2 | Avatar | $270,243 | -19.4% | 26 | - | $10,393 | $10,343,999 | 9 | 20th Century Fox International | false | false |
| 6 | 3 | Cloudy with a Chance of Meatballs | $202,805 | -36.5% | 55 | -22 | $3,687 | $1,014,709 | 3 | Sony Pictures Releasing | false | false |
| 7 | 4 | I Love Karditsa | $198,414 | -35.4% | 47 | -9 | $4,221 | $3,930,665 | 5 | Odeon | false | false |
| 8 | 5 | Dangerous Cooking | $121,315 | -55.9% | 69 | -6 | $1,758 | $511,000 | 2 | Odeon | false | false |
| 9 | 6 | Sherlock Holmes | $87,111 | -51.3% | 36 | -20 | $2,419 | $2,927,097 | 5 | Roadshow Films | false | false |
| 10 | 7 | Agora | $69,261 | -34.6% | 22 | -1 | $3,148 | $492,943 | 3 | Odeon | false | false |
| 11 | 11 | Did You Hear About the Morgans? | $2,619 | -85.5% | 4 | -5 | $654 | $784,818 | 6 | Sony Pictures Releasing | false | false |
