| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $914,470 | -5.9% | 196 | - | $4,665 | $11,329,331 | 7 | 20th Century Fox International | false | false |
| 2 | 2 | Sherlock Holmes | $372,506 | -11% | 75 | - | $4,966 | $2,127,088 | 4 | Warner Bros. | false | false |
| 3 | - | Did You Hear About the Morgans? | $353,796 | - | 27 | - | $13,103 | $382,397 | 1 | Sony Pictures Releasing | true | false |
| 4 | 4 | Alvin and the Chipmunks: The Squeakquel | $211,786 | -25.5% | 93 | - | $2,277 | $3,841,298 | 6 | 20th Century Fox International | false | false |
| 5 | 3 | Up in the Air | $211,763 | -29.6% | 25 | - | $8,470 | $622,184 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | - | Oceans | $168,357 | - | 26 | - | $6,475 | $168,357 | 1 | Alternative Films | true | false |
| 7 | 10 | Cloudy with a Chance of Meatballs | $167,830 | +156.4% | 42 | +19 | $3,995 | $601,196 | 3 | Sony Pictures Releasing | false | false |
| 8 | 5 | Dossier K. | $147,552 | -18.3% | 35 | -1 | $4,215 | $3,424,196 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 9 | - | The Road | $143,892 | - | 23 | - | $6,256 | $173,704 | 1 | Benelux Film Distributors | true | false |
| 10 | 6 | Mr. Nobody | $127,098 | -28.6% | 35 | -1 | $3,631 | $619,140 | 3 | Belga Films | false | false |
| 11 | 7 | Invictus | $105,645 | -34.1% | 25 | - | $4,225 | $519,152 | 3 | Warner Bros. | false | false |
| 12 | 8 | It's Complicated | $77,411 | -36.8% | 43 | +1 | $1,800 | $1,399,076 | 6 | Universal Pictures International (UPI) | false | false |
| 13 | 9 | A Serious Man | $75,560 | -30.9% | 13 | - | $5,812 | $221,184 | 2 | Universal Pictures International (UPI) | false | false |
| 14 | 11 | Plop en de kabouterbaby | $45,157 | -26% | 31 | -2 | $1,456 | $1,475,119 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 15 | 13 | The Twilight Saga: New Moon | $40,339 | -21.3% | 23 | -4 | $1,753 | $6,922,337 | 11 | Belga Films | false | false |
| 16 | 14 | Anubis en de wraak van Arghus | $37,728 | -24% | 29 | - | $1,300 | $1,009,345 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 17 | 12 | The Men Who Stare at Goats | $36,439 | -33.6% | 14 | - | $2,602 | $248,245 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 18 | 16 | The Barons | $22,663 | -36.1% | 12 | +2 | $1,888 | $1,285,011 | 13 | Cinéart | false | false |
| 19 | 19 | Arthur and the Revenge of Maltazard | $22,445 | -34.2% | 21 | -8 | $1,068 | $2,143,974 | 9 | Belga Films | false | false |
| 20 | 15 | The Girl Who Played with Fire | $20,637 | -50.6% | 21 | - | $982 | $149,139 | 3 | Benelux Film Distributors | false | false |
| 21 | 21 | Paranormal Activity | $19,887 | -24.6% | 13 | -3 | $1,529 | $1,148,225 | 10 | Kinepolis Film Distribution (KFD) | false | false |
| 22 | 17 | The Whistler | $18,547 | -46.8% | 13 | - | $1,426 | $209,887 | 4 | Benelux Film Distributors | false | false |
| 23 | 20 | The Concert | $17,980 | -38.3% | 8 | -7 | $2,247 | $799,983 | 12 | Cinéart | false | false |
| 24 | 18 | 2012 | $17,960 | -48% | 11 | -6 | $1,632 | $6,317,048 | 12 | Sony Pictures Releasing | false | false |
| 25 | 30 | Bright Star | $16,437 | +157.6% | 6 | -1 | $2,739 | $103,122 | 8 | Paradiso Entertainment | false | false |
| 26 | - | No One Knows About Persian Cats | $11,702 | - | 5 | - | $2,340 | $15,366 | 1 | Cinéart | true | false |
| 27 | 23 | Capitalism: A Love Story | $11,566 | -14.3% | 9 | - | $1,285 | $132,446 | 4 | Paradiso Entertainment | false | false |
| 28 | 24 | Das Lied der Dinge | $8,735 | -32.3% | 11 | -8 | $794 | $3,630,085 | 17 | Kinepolis Film Distribution (KFD) | false | false |
| 29 | 26 | Brothers | $8,053 | -19.9% | 7 | - | $1,150 | $269,406 | 6 | A-Film Distribution | false | false |
| 30 | 22 | Oscar and the Lady in Pink | $7,397 | -51% | 13 | -8 | $569 | $330,546 | 7 | Cinéart | false | false |
| 31 | 25 | Couples Retreat | $5,281 | -48.6% | 3 | -1 | $1,760 | $517,362 | 9 | Universal Pictures International (UPI) | false | false |
| 32 | 29 | The Ordinary People | $4,900 | -37.7% | 5 | - | $980 | $16,297 | 2 | Cinéart | false | false |
| 33 | 31 | Altiplano | $4,743 | -13.5% | 5 | - | $948 | $136,001 | 10 | N/A | false | false |
| 34 | - | Up | $4,110 | - | 1 | - | $4,110 | $7,088,865 | 17 | Walt Disney Pictures | false | false |
| 35 | 28 | Creation | $3,961 | -55.9% | 5 | - | $792 | $20,887 | 2 | A-Film Distribution | false | false |
| 36 | 27 | Coco Chanel & Igor Stravinsky | $3,313 | -65.2% | 6 | -1 | $552 | $71,499 | 4 | Cinéart | false | false |
| 37 | 32 | Where the Wild Things Are | $2,841 | -36% | 5 | -5 | $568 | $117,817 | 5 | Warner Bros. | false | false |
| 38 | - | Love Life | $2,036 | - | 2 | - | $1,018 | $148,415 | 9 | Benelux Film Distributors | false | false |
| 39 | - | A Christmas Carol | $924 | - | 7 | - | $132 | $1,769,393 | 11 | Walt Disney Pictures | false | false |
| 40 | - | Remembering the Children | $898 | - | 4 | - | $224 | $16,814 | 7 | Benelux Film Distributors | false | false |
| 41 | - | Krabat and the Legend of the Satanic Mill | $256 | - | 1 | - | $256 | $256 | 1 | Jekino | true | false |
