| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $712,252 | -8.5% | 89 | -3 | $8,002 | $8,518,854 | 6 | 20th Century Fox International | false | false |
| 2 | - | It's Complicated | $320,208 | - | 57 | - | $5,617 | $320,208 | 1 | United International Pictures | true | false |
| 3 | 3 | Alvin and the Chipmunks: The Squeakquel | $189,912 | -13.1% | 75 | - | $2,532 | $2,432,924 | 5 | 20th Century Fox International | false | false |
| 4 | 2 | Sherlock Holmes | $184,053 | -17% | 69 | -6 | $2,667 | $2,381,643 | 5 | Roadshow Films | false | false |
| 5 | 4 | Tooth Fairy | $181,765 | -8.8% | 63 | +2 | $2,885 | $503,010 | 2 | 20th Century Fox International | false | false |
| 6 | 5 | The Lovely Bones | $129,129 | -33.3% | 61 | - | $2,116 | $2,159,946 | 5 | Paramount Pictures International | false | false |
| 7 | 7 | Up in the Air | $118,254 | -12.3% | 20 | - | $5,912 | $305,833 | 2 | Paramount Pictures International | false | false |
| 8 | 6 | Paranormal Activity | $96,542 | -38.1% | 47 | +1 | $2,054 | $778,850 | 4 | Icon Film Distribution | false | false |
| 9 | 8 | Fantastic Mr. Fox | $80,219 | -13% | 48 | - | $1,671 | $408,041 | 3 | 20th Century Fox International | false | false |
| 10 | 9 | Old Dogs | $66,252 | -28.1% | 46 | - | $1,440 | $439,444 | 3 | Walt Disney Pictures | false | false |
| 11 | - | Astro Boy | $66,252 | - | 46 | - | $1,440 | $439,444 | 1 | Hoyts Distribution | true | false |
| 12 | 11 | The Girl with the Dragon Tattoo | $52,409 | -4.3% | 34 | +1 | $1,541 | $434,958 | 6 | Rialto Distribution | false | false |
| 13 | 10 | The Princess and the Frog | $49,306 | -18.7% | 59 | - | $835 | $510,480 | 4 | Walt Disney Pictures | false | false |
| 14 | 16 | Mid-August Lunch | $16,328 | +34.1% | 8 | - | $2,041 | $80,775 | 3 | Rialto Distribution | false | false |
| 15 | 12 | Whip It | $13,879 | -52.4% | 24 | -15 | $578 | $144,976 | 3 | Roadshow Films | false | false |
| 16 | - | Veer | $8,759 | - | 3 | - | $2,919 | $8,759 | 1 | - | true | false |
| 17 | 17 | Creation | $7,764 | -24.6% | 22 | -1 | $352 | $103,045 | 5 | Icon Film Distribution | false | false |
| 18 | 20 | Julie & Julia | $7,663 | -10.5% | 10 | -1 | $766 | $1,372,861 | 14 | Sony Pictures Releasing | false | false |
| 19 | 29 | My Sister's Keeper | $7,457 | +280.3% | 11 | -2 | $677 | $936,590 | 12 | Roadshow Films | false | false |
| 20 | 19 | Where the Wild Things Are | $7,418 | -19.2% | 27 | +3 | $274 | $890,310 | 8 | Roadshow Films | false | false |
| 21 | 15 | The Twilight Saga: New Moon | $6,666 | -47.9% | 16 | -8 | $416 | $4,325,191 | 10 | Hoyts Distribution | false | false |
| 22 | - | Noodle | $5,644 | - | 11 | - | $513 | $5,644 | 1 | - | true | false |
| 23 | 21 | The Time Traveler's Wife | $5,183 | -19.4% | 20 | +4 | $259 | $601,511 | 8 | Roadshow Films | false | false |
| 24 | 18 | 3 Idiots | $3,867 | -58.4% | 4 | -1 | $966 | $174,760 | 5 | Mind Blowing Films | false | false |
| 25 | 14 | Cirque du Freak: The Vampire's Assistant | $3,771 | -75.2% | 11 | -11 | $342 | $81,318 | 3 | United International Pictures | false | false |
| 26 | 23 | Chance Pe Dance | $2,516 | -40.6% | 2 | - | $1,258 | $8,782 | 2 | Mind Blowing Films | false | false |
| 27 | 24 | Planet 51 | $1,976 | -38.9% | 13 | -1 | $152 | $285,486 | 7 | Hoyts Distribution | false | false |
| 28 | 26 | Five Minutes of Heaven | $1,867 | -35.2% | 6 | -2 | $311 | $29,137 | 6 | Madman Entertainment | false | false |
| 29 | 13 | Offenbach: Les contes d'Hoffmann | $1,655 | -93.8% | 2 | -10 | $827 | $45,473 | 2 | Rialto Distribution | false | false |
| 30 | 22 | Whatever Works | $1,384 | -68.4% | 7 | -3 | $197 | $19,035 | 3 | Hopscotch Films | false | false |
| 31 | 25 | Cold Souls | $1,339 | -55.2% | 2 | - | $669 | $5,249 | 2 | Madman Entertainment | false | false |
| 32 | 30 | Departures | $1,241 | -22.5% | 6 | -2 | $206 | $196,435 | 23 | Madman Entertainment | false | false |
| 33 | 31 | In the Loop | $996 | -27.2% | 4 | - | $249 | $351,070 | 17 | Madman Entertainment | false | false |
| 34 | 32 | Looking for Eric | $823 | -25.5% | 4 | -3 | $205 | $116,942 | 9 | Icon Film Distribution | false | false |
| 35 | 28 | Amelia | $808 | -61.4% | 3 | -3 | $269 | $123,933 | 7 | 20th Century Fox International | false | false |
| 36 | 33 | Valentino: The Last Emperor | $760 | -28% | 2 | -1 | $380 | $67,686 | 9 | Hopscotch Films | false | false |
| 37 | 41 | The Imaginarium of Doctor Parnassus | $565 | +2,254.2% | 2 | +1 | $282 | $251,101 | 12 | Hoyts Distribution | false | false |
| 38 | 34 | Mary and Max | $460 | -46.3% | 3 | -1 | $153 | $53,240 | 9 | Icon Film Distribution | false | false |
| 39 | 36 | Bandslam | $433 | +26.2% | 3 | -2 | $144 | $84,408 | 6 | Hoyts Distribution | false | false |
| 40 | 27 | Pyaar Impossible | $324 | -86.8% | 1 | -1 | $324 | $9,035 | 3 | Forum Hungary | false | false |
| 41 | 37 | A Heavenly Vintage | $53 | -74.5% | 2 | -1 | $26 | $136,750 | 11 | Icon Film Distribution | false | false |
