| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $778,496 | -13.6% | 92 | +3 | $8,461 | $7,650,456 | 5 | 20th Century Fox International | false | false |
| 2 | 2 | Sherlock Holmes | $221,713 | -29% | 75 | - | $2,956 | $2,167,026 | 4 | Roadshow Films | false | false |
| 3 | 3 | Alvin and the Chipmunks: The Squeakquel | $218,507 | -28.2% | 75 | -1 | $2,913 | $2,180,261 | 4 | 20th Century Fox International | false | false |
| 4 | - | Tooth Fairy | $199,211 | - | 61 | - | $3,265 | $199,211 | 1 | 20th Century Fox International | true | false |
| 5 | 4 | The Lovely Bones | $193,528 | -32% | 61 | - | $3,172 | $2,007,009 | 4 | Paramount Pictures International | false | false |
| 6 | 5 | Paranormal Activity | $156,001 | -40.5% | 46 | +4 | $3,391 | $630,256 | 3 | Icon Film Distribution | false | false |
| 7 | - | Up in the Air | $134,850 | - | 20 | - | $6,742 | $134,850 | 1 | Paramount Pictures International | true | false |
| 8 | 7 | Fantastic Mr. Fox | $92,192 | -10.8% | 48 | - | $1,920 | $292,170 | 2 | 20th Century Fox International | false | false |
| 9 | 6 | Old Dogs | $92,137 | -40.1% | 46 | - | $2,002 | $341,754 | 2 | Walt Disney Pictures | false | false |
| 10 | 8 | The Princess and the Frog | $60,681 | -30.6% | 59 | - | $1,028 | $437,242 | 3 | Walt Disney Pictures | false | false |
| 11 | 9 | The Girl with the Dragon Tattoo | $54,751 | -13.3% | 33 | - | $1,659 | $369,315 | 5 | Rialto Distribution | false | false |
| 12 | 10 | Whip It | $29,134 | -44.4% | 39 | - | $747 | $116,273 | 2 | Roadshow Films | false | false |
| 13 | - | Offenbach: Les contes d'Hoffmann | $26,731 | - | 12 | - | $2,227 | $116,273 | 1 | Rialto Distribution | true | false |
| 14 | 11 | Cirque du Freak: The Vampire's Assistant | $15,231 | -50.8% | 22 | -4 | $692 | $69,033 | 2 | United International Pictures | false | false |
| 15 | 12 | The Twilight Saga: New Moon | $12,801 | -37.5% | 24 | -8 | $533 | $4,472,765 | 9 | Hoyts Distribution | false | false |
| 16 | 14 | Mid-August Lunch | $12,176 | -29.4% | 8 | +1 | $1,522 | $59,808 | 2 | Rialto Distribution | false | false |
| 17 | 15 | Creation | $10,297 | -31.6% | 23 | +1 | $447 | $92,076 | 4 | Icon Film Distribution | false | false |
| 18 | 13 | 3 Idiots | $9,289 | -53.4% | 5 | - | $1,857 | $173,449 | 4 | Mind Blowing Films | false | false |
| 19 | 16 | Where the Wild Things Are | $9,179 | -26.7% | 24 | +3 | $382 | $917,359 | 7 | Roadshow Films | false | false |
| 20 | 17 | Julie & Julia | $8,561 | -4.2% | 11 | -2 | $778 | $1,412,664 | 13 | Sony Pictures Releasing | false | false |
| 21 | 19 | The Time Traveler's Wife | $6,431 | +4.7% | 16 | +4 | $401 | $615,892 | 7 | Roadshow Films | false | false |
| 22 | 18 | Whatever Works | $4,383 | -43.6% | 10 | - | $438 | $16,660 | 2 | Hopscotch Films | false | false |
| 23 | - | Chance Pe Dance | $4,235 | - | 2 | - | $2,117 | $4,235 | 1 | Mind Blowing Films | true | false |
| 24 | 20 | Planet 51 | $3,236 | -40.9% | 14 | -1 | $231 | $291,236 | 6 | Hoyts Distribution | false | false |
| 25 | - | Cold Souls | $2,991 | - | 2 | - | $1,495 | $2,991 | 1 | Madman Entertainment | true | false |
| 26 | 23 | Five Minutes of Heaven | $2,882 | -17.5% | 8 | - | $360 | $27,245 | 5 | Madman Entertainment | false | false |
| 27 | 22 | Pyaar Impossible | $2,455 | -32.1% | 2 | - | $1,227 | $7,998 | 2 | Forum Hungary | false | false |
| 28 | 24 | Amelia | $2,093 | -22.2% | 6 | -3 | $348 | $127,375 | 6 | 20th Century Fox International | false | false |
| 29 | 21 | My Sister's Keeper | $1,961 | -59.6% | 13 | +1 | $150 | $953,687 | 11 | Roadshow Films | false | false |
| 30 | 30 | Departures | $1,601 | +56.2% | 8 | - | $200 | $202,322 | 22 | Madman Entertainment | false | false |
| 31 | 25 | In the Loop | $1,368 | -46% | 4 | +1 | $342 | $363,134 | 16 | Madman Entertainment | false | false |
| 32 | 28 | Looking for Eric | $1,104 | -18.1% | 7 | -1 | $157 | $120,163 | 8 | Icon Film Distribution | false | false |
| 33 | 29 | Valentino: The Last Emperor | $1,055 | -4.8% | 3 | +1 | $351 | $69,322 | 8 | Hopscotch Films | false | false |
| 34 | 27 | Mary and Max | $856 | -44.7% | 4 | -1 | $214 | $54,414 | 8 | Icon Film Distribution | false | false |
| 35 | 35 | Under the Mountain | $634 | -8.8% | 7 | +2 | $90 | $203,502 | 6 | Walt Disney Pictures | false | false |
| 36 | 34 | Bandslam | $343 | -60% | 5 | -4 | $68 | $86,264 | 5 | Hoyts Distribution | false | false |
| 37 | 36 | A Heavenly Vintage | $208 | -57% | 3 | -2 | $69 | $141,852 | 10 | Icon Film Distribution | false | false |
| 38 | 37 | The Strength of Water | $66 | -68.3% | 1 | - | $66 | $163,650 | 21 | Hopscotch Films | false | false |
| 39 | 38 | Surrogates | $44 | -70.1% | 1 | - | $44 | $590,531 | 13 | Walt Disney Pictures | false | false |
| 40 | 41 | What Just Happened | $30 | +150% | 1 | - | $30 | $17,816 | 9 | Hopscotch Films | false | false |
| 41 | 39 | The Imaginarium of Doctor Parnassus | $24 | -78.8% | 1 | - | $24 | $260,357 | 11 | Hoyts Distribution | false | false |
