| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $859,729 | +16.5% | 92 | - | $9,344 | $4,507,637 | 3 | 20th Century Fox International | false | false |
| 2 | 3 | Sherlock Holmes | $401,971 | +33.3% | 76 | - | $5,289 | $1,107,526 | 2 | Roadshow Films | false | false |
| 3 | 2 | The Lovely Bones | $326,213 | +7.6% | 63 | - | $5,177 | $1,018,061 | 2 | Paramount Pictures International | false | false |
| 4 | 4 | Alvin and the Chipmunks: The Squeakquel | $324,337 | +25.8% | 83 | - | $3,907 | $1,041,736 | 2 | 20th Century Fox International | false | false |
| 5 | - | The Princess and the Frog | $100,101 | - | 61 | - | $1,641 | $100,101 | 1 | Walt Disney Pictures | true | false |
| 6 | 5 | The Girl with the Dragon Tattoo | $73,341 | +51.5% | 31 | - | $2,365 | $183,188 | 3 | Rialto Distribution | false | false |
| 7 | - | Paranormal Activity | $51,889 | - | 35 | - | $1,482 | $65,037 | 1 | Icon Film Distribution | true | false |
| 8 | 8 | 3 Idiots | $40,559 | +62.7% | 5 | +1 | $8,111 | $103,819 | 2 | Mind Blowing Films | false | false |
| 9 | 6 | The Twilight Saga: New Moon | $38,121 | +11.4% | 61 | -18 | $624 | $4,297,076 | 7 | Hoyts Distribution | false | false |
| 10 | 7 | Where the Wild Things Are | $28,163 | -5.1% | 45 | -3 | $625 | $841,132 | 5 | Roadshow Films | false | false |
| 11 | 11 | Creation | $17,691 | +73% | 23 | +3 | $769 | $44,217 | 2 | Icon Film Distribution | false | false |
| 12 | 9 | The Time Traveler's Wife | $15,129 | +2.5% | 24 | -14 | $630 | $571,140 | 5 | Roadshow Films | false | false |
| 13 | 10 | Planet 51 | $11,716 | -2.6% | 35 | -6 | $334 | $256,329 | 4 | Hoyts Distribution | false | false |
| 14 | 12 | Julie & Julia | $11,553 | +35.7% | 14 | +1 | $825 | $1,351,124 | 11 | Sony Pictures Releasing | false | false |
| 15 | - | The First Day of the Rest of Your Life | $8,871 | - | 11 | - | $806 | $67,669 | 4 | Rialto Distribution | false | false |
| 16 | - | Bodyguards and Assassins | $8,510 | - | 3 | - | $2,836 | $8,510 | 1 | - | true | false |
| 17 | 18 | Amelia | $7,296 | +56.4% | 12 | -14 | $608 | $115,244 | 4 | 20th Century Fox International | false | false |
| 18 | 13 | Under the Mountain | $6,580 | -21.6% | 26 | -21 | $253 | $189,152 | 4 | Walt Disney Pictures | false | false |
| 19 | 16 | Bandslam | $5,884 | +10% | 33 | -12 | $178 | $73,393 | 3 | Hoyts Distribution | false | false |
| 20 | 15 | Zombieland | $5,210 | -28.4% | 11 | -18 | $473 | $468,424 | 5 | Sony Pictures Releasing | false | false |
| 21 | 17 | 2012 | $4,742 | -0.9% | 9 | -7 | $526 | $2,057,977 | 8 | Sony Pictures Releasing | false | false |
| 22 | 14 | Cloudy with a Chance of Meatballs | $3,709 | -49.7% | 15 | -30 | $247 | $501,916 | 6 | Sony Pictures Releasing | false | false |
| 23 | 22 | Five Minutes of Heaven | $3,463 | +95.9% | 8 | - | $432 | $14,225 | 3 | Madman Entertainment | false | false |
| 24 | 20 | The Storm Warriors | $2,638 | -23.1% | 5 | -2 | $527 | $73,480 | 4 | Vendetta Films | false | false |
| 25 | 25 | Looking for Eric | $2,512 | +117.9% | 8 | -1 | $314 | $111,448 | 6 | Icon Film Distribution | false | false |
| 26 | 21 | My Sister's Keeper | $2,402 | +14.8% | 14 | -6 | $171 | $922,257 | 9 | Roadshow Films | false | false |
| 27 | 26 | In the Loop | $2,339 | +143.9% | 3 | - | $779 | $341,663 | 14 | Madman Entertainment | false | false |
| 28 | 27 | Mary and Max | $1,277 | +106% | 3 | -1 | $425 | $49,504 | 6 | Icon Film Distribution | false | false |
| 29 | - | Valentino: The Last Emperor | $1,095 | - | 2 | - | $547 | $61,996 | 6 | Hopscotch Films | false | false |
| 30 | 23 | Coco Before Chanel | $908 | -27.2% | 2 | -2 | $454 | $572,644 | 22 | Warner Bros. | false | false |
| 31 | 24 | The Informant! | $815 | -31.9% | 2 | -6 | $407 | $82,039 | 5 | Warner Bros. | false | false |
| 32 | - | Departures | $703 | - | 6 | - | $117 | $193,830 | 20 | Madman Entertainment | false | false |
| 33 | 29 | A Heavenly Vintage | $516 | +57.8% | 4 | - | $129 | $136,860 | 8 | Icon Film Distribution | false | false |
| 34 | 19 | A Christmas Carol | $452 | -90.2% | 1 | -24 | $452 | $512,006 | 9 | Walt Disney Pictures | false | false |
| 35 | 31 | The Imaginarium of Doctor Parnassus | $380 | +224.8% | 3 | +1 | $126 | $255,192 | 9 | Hoyts Distribution | false | false |
| 36 | - | Surrogates | $143 | - | 1 | - | $143 | $579,061 | 11 | Walt Disney Pictures | false | false |
| 37 | - | G-Force | $128 | - | 1 | - | $128 | $1,261,251 | 15 | Walt Disney Pictures | false | false |
