| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Up | $1,145,352 | +98.4% | 128 | -2 | $8,948 | $5,876,921 | 5 | Walt Disney Pictures | false | false |
| 2 | 1 | This Is It | $759,799 | -27.9% | 62 | - | $12,254 | $2,193,804 | 2 | Sony Pictures Releasing | false | false |
| 3 | 3 | Das Lied der Dinge | $414,912 | +7.5% | 31 | - | $13,384 | $2,445,648 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 4 | - | The Box | $326,406 | - | 28 | - | $11,657 | $331,404 | 1 | Benelux Film Distributors | true | false |
| 5 | - | Cirque du Freak: The Vampire's Assistant | $270,359 | - | 30 | - | $9,011 | $322,697 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 5 | Fame | $236,727 | +32.8% | 46 | - | $5,146 | $1,766,325 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 7 | 4 | Surrogates | $227,537 | -21.5% | 53 | - | $4,293 | $1,023,775 | 3 | Walt Disney Pictures | false | false |
| 8 | 8 | Little Nicholas | $200,611 | +54.6% | 30 | - | $6,687 | $1,454,567 | 6 | Cinéart | false | false |
| 9 | - | The Barons | $155,268 | - | 10 | - | $15,526 | $160,689 | 1 | Cinéart | true | false |
| 10 | 13 | Astro Boy | $151,600 | +126.3% | 43 | -1 | $3,525 | $322,895 | 2 | Belga Films | false | false |
| 11 | 7 | Dance Flick | $133,275 | -1.8% | 21 | +1 | $6,346 | $370,770 | 2 | Universal Pictures International (UPI) | false | false |
| 12 | 6 | Micmacs | $101,085 | -32.5% | 16 | -29 | $6,317 | $313,996 | 2 | Cinéart | false | false |
| 13 | 10 | Lucky Luke | $94,789 | +10.8% | 24 | - | $3,949 | $390,496 | 3 | Les Films de l'Elysée | false | false |
| 14 | 9 | Jennifer's Body | $81,112 | -33.5% | 35 | - | $2,317 | $530,458 | 3 | 20th Century Fox International | false | false |
| 15 | 15 | G-Force | $80,411 | +102.1% | 32 | -5 | $2,512 | $2,999,254 | 15 | Walt Disney Pictures | false | false |
| 16 | - | 500 Days of Summer | $72,786 | - | 11 | - | $6,616 | $97,381 | 1 | 20th Century Fox International | true | false |
| 17 | 11 | Inglourious Basterds | $67,740 | -13.9% | 30 | -17 | $2,258 | $5,094,433 | 12 | Universal Pictures International (UPI) | false | false |
| 18 | 20 | Sinterklaas en de verdwenen pakjesboot | $60,826 | +176% | 11 | - | $5,529 | $106,709 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 19 | 12 | The Ugly Truth | $57,296 | -16.5% | 25 | -4 | $2,291 | $1,500,044 | 7 | Sony Pictures Releasing | false | false |
| 20 | 23 | Lilly the Witch: The Dragon and the Magic Book | $54,731 | +256.6% | 10 | - | $5,473 | $142,065 | 38 | Kinepolis Film Distribution (KFD) | false | false |
| 21 | 14 | The White Ribbon | $51,066 | -17.6% | 16 | - | $3,191 | $251,961 | 3 | Cinéart | false | false |
| 22 | - | Whiteout | $35,511 | - | 12 | - | $2,959 | $54,362 | 1 | Universal Pictures International (UPI) | true | false |
| 23 | 25 | Ice Age: Dawn of the Dinosaurs | $27,638 | +100.6% | 16 | - | $1,727 | $9,755,324 | 19 | 20th Century Fox International | false | false |
| 24 | 18 | My Queen Karo | $26,841 | -1% | 10 | - | $2,684 | $68,158 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 25 | 17 | Whatever Works | $22,450 | -28.5% | 9 | -2 | $2,494 | $373,517 | 6 | Paradiso Entertainment | false | false |
| 26 | 16 | District 9 | $16,894 | -54.4% | 12 | -10 | $1,407 | $871,010 | 6 | Sony Pictures Releasing | false | false |
| 27 | - | Wild Grass | $12,038 | - | 7 | - | $1,719 | $12,936 | 1 | N/A | true | false |
| 28 | 27 | A Perfect Getaway | $10,767 | +1.8% | 1 | - | $10,767 | $693,518 | 11 | A-Film Distribution | false | false |
| 29 | - | Departures | $10,477 | - | 4 | - | $2,619 | $13,168 | 1 | N/A | true | false |
| 30 | - | Het geheim van Mega Mindy | $9,254 | - | 1 | - | $9,254 | $1,731,315 | 19 | Kinepolis Film Distribution (KFD) | false | false |
| 31 | 26 | The Storm | $8,607 | -32.3% | 6 | +1 | $1,434 | $134,457 | 6 | Universal Pictures International (UPI) | false | false |
| 32 | 28 | The Taking of Pelham 123 | $8,064 | -17.4% | 1 | -1 | $8,064 | $1,562,363 | 15 | Sony Pictures Releasing | false | false |
| 33 | 19 | Julie & Julia | $8,045 | -67.5% | 5 | -7 | $1,609 | $265,006 | 4 | Sony Pictures Releasing | false | false |
| 34 | 21 | The Final Destination | $7,364 | -64.2% | 7 | -16 | $1,052 | $1,405,282 | 8 | Warner Bros. | false | false |
