| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | This Is It | $22,131 | - | 6 | - | $3,688 | $22,131 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Inglourious Basterds | $14,794 | -59.5% | 8 | - | $1,849 | $105,834 | 3 | United International Pictures | false | false |
| 3 | - | Halloween II | $13,954 | - | 5 | - | $2,790 | $13,954 | 1 | N/A | true | false |
| 4 | 3 | Surrogates | $12,618 | -18.4% | 6 | - | $2,103 | $94,211 | 4 | Walt Disney Pictures | false | false |
| 5 | - | Management | $11,925 | - | 3 | - | $3,975 | $11,925 | 1 | N/A | true | false |
| 6 | 2 | The Ugly Truth | $10,624 | -34.5% | 6 | - | $1,770 | $172,661 | 6 | Sony Pictures Releasing | false | false |
| 7 | 6 | Arn: The Knight Templar | $9,629 | -20.9% | 5 | - | $1,925 | $23,915 | 2 | - | false | false |
| 8 | 5 | The Final Destination | $9,182 | -26% | 4 | -1 | $2,295 | $218,798 | 7 | Warner Bros. | false | false |
| 9 | 4 | Funny People | $8,439 | -32.1% | 5 | - | $1,687 | $22,852 | 2 | United International Pictures | false | false |
| 10 | 7 | Whiteout | $5,803 | -48.3% | 5 | - | $1,160 | $19,080 | 2 | Warner Bros. | false | false |
| 11 | 9 | I Hate Valentine's Day | $4,206 | -38.2% | 3 | - | $1,402 | $24,250 | 3 | - | false | false |
| 12 | 8 | Orphan | $3,808 | -64.4% | 2 | -3 | $1,904 | $79,394 | 5 | Warner Bros. | false | false |
| 13 | 10 | Jennifer's Body | $3,413 | -47.6% | 3 | - | $1,137 | $33,604 | 4 | 20th Century Fox International | false | false |
| 14 | 15 | Cloudy with a Chance of Meatballs | $1,889 | +1.5% | 3 | - | $629 | $40,046 | 7 | Sony Pictures Releasing | false | false |
| 15 | 14 | G.I. Joe: The Rise of Cobra | $1,747 | -20.7% | 6 | -1 | $291 | $100,654 | 6 | United International Pictures | false | false |
| 16 | 11 | Red Cliff | $1,452 | -70.8% | 2 | -2 | $726 | $28,670 | 4 | - | false | false |
| 17 | 12 | Land of the Lost | $1,018 | -71.6% | 2 | -4 | $509 | $33,167 | 5 | United International Pictures | false | false |
| 18 | 16 | The Flight Before Christmas | $956 | -35.9% | 2 | - | $478 | $4,475 | 3 | - | false | false |
| 19 | 19 | Imagine That | $324 | -45.2% | 2 | - | $162 | $64,412 | 13 | United International Pictures | false | false |
| 20 | 17 | Blood: The Last Vampire | $234 | -76.5% | 2 | -1 | $117 | $5,513 | 3 | N/A | false | false |
| 21 | 20 | The Other Man | $113 | -75.5% | 1 | -2 | $113 | $21,203 | 5 | N/A | false | false |
