| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | G-Force | $43,708 | -22.3% | 12 | - | $3,642 | $129,246 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | The Ugly Truth | $22,006 | -7.4% | 7 | - | $3,143 | $129,193 | 3 | Sony Pictures Releasing | false | false |
| 3 | - | Orphan | $19,596 | - | 7 | - | $2,799 | $20,482 | 1 | - | true | false |
| 4 | 3 | The Final Destination | $13,007 | -16.6% | 6 | - | $2,167 | $181,356 | 4 | - | false | false |
| 5 | - | Pandorum | $10,969 | - | 4 | - | $2,742 | $10,969 | 1 | ACME | true | false |
| 6 | 5 | Up | $9,490 | -10.9% | 10 | +1 | $949 | $400,741 | 6 | Universal Pictures International (UPI) | false | false |
| 7 | 4 | Inglourious Basterds | $8,056 | -28.9% | 6 | - | $1,342 | $8,056 | 5 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | High Security Vacation | $5,528 | -23.8% | 4 | - | $1,382 | $59,586 | 4 | ACME | false | false |
| 9 | 7 | Vortex | $2,823 | -15.6% | 3 | - | $941 | $33,161 | 16 | N/A | false | false |
| 10 | 8 | Ice Age: Dawn of the Dinosaurs | $2,566 | -16.2% | 4 | -1 | $641 | $1,410,392 | 13 | Universal Pictures International (UPI) | false | false |
| 11 | 10 | Whatever Works | $2,032 | +32.6% | 1 | - | $2,032 | $5,164 | 2 | ACME | false | false |
| 12 | 9 | My Sister's Keeper | $1,538 | -41.6% | 4 | - | $384 | $114,375 | 8 | - | false | false |
| 13 | 12 | Diary of a Nymphomaniac | $943 | +13.8% | 2 | - | $471 | $38,114 | 8 | ACME | false | false |
| 14 | 16 | The Last House on the Left | $559 | +104% | 2 | - | $279 | $31,250 | 10 | Universal Pictures International (UPI) | false | false |
| 15 | 13 | Dream | $429 | -35.9% | 1 | - | $429 | $2,148 | 3 | N/A | false | false |
| 16 | 15 | Harry Potter and the Half-Blood Prince | $365 | -5.9% | 2 | -5 | $182 | $320,186 | 10 | Garsu Pasaulio Irasai | false | false |
| 17 | 14 | G.I. Joe: The Rise of Cobra | $362 | -28.3% | 3 | +1 | $120 | $55,390 | 7 | Universal Pictures International (UPI) | false | false |
| 18 | - | Ricky | $315 | - | 1 | - | $315 | $315 | 1 | N/A | true | false |
| 19 | 11 | District 9 | $275 | -67.6% | 7 | - | $39 | $96,771 | 7 | Sony Pictures Releasing | false | false |
| 20 | - | Gomorrah | $205 | - | 1 | - | $205 | $26,745 | 11 | Universal Pictures International (UPI) | false | false |
| 21 | 20 | Easy Virtue | $186 | +52.5% | 1 | - | $186 | $19,128 | 9 | ACME | false | false |
| 22 | 17 | Hannah Montana: The Movie | $115 | -54.7% | 2 | - | $57 | $30,818 | 9 | Universal Pictures International (UPI) | false | false |
| 23 | 18 | Let the Right One In | $64 | -66.1% | 1 | - | $64 | $9,545 | 6 | Universal Pictures International (UPI) | false | false |
| 24 | 19 | Lorna's Silence | $44 | -76% | 1 | -1 | $44 | $2,742 | 5 | N/A | false | false |
