| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Ugly Truth | $360,129 | - | 35 | - | $10,289 | $407,691 | 1 | Sony Pictures Releasing | true | false |
| 2 | 2 | Inglourious Basterds | $266,035 | -11.8% | 65 | - | $4,092 | $3,880,013 | 6 | Universal Pictures International (UPI) | false | false |
| 3 | 1 | The Final Destination | $220,999 | -36.8% | 41 | - | $5,390 | $821,203 | 2 | Warner Bros. | false | false |
| 4 | 4 | G-Force | $76,597 | -1.6% | 61 | -10 | $1,255 | $2,388,269 | 9 | Walt Disney Pictures | false | false |
| 5 | - | The Hurt Locker | $72,061 | - | 16 | - | $4,503 | $75,452 | 1 | Belga Films | true | false |
| 6 | 3 | Ice Age: Dawn of the Dinosaurs | $70,451 | -18.9% | 63 | -11 | $1,118 | $8,992,287 | 13 | 20th Century Fox International | false | false |
| 7 | 7 | A Perfect Getaway | $53,507 | -17.7% | 23 | - | $2,326 | $512,627 | 5 | A-Film Distribution | false | false |
| 8 | 6 | The Over the Hill Band | $52,407 | -21.7% | 24 | - | $2,183 | $634,763 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 9 | 5 | Gamer | $44,618 | -39.7% | 34 | - | $1,312 | $289,711 | 3 | Benelux Film Distributors | false | false |
| 10 | 9 | Harry Potter and the Half-Blood Prince | $41,261 | -22.8% | 63 | -22 | $654 | $8,858,781 | 11 | Warner Bros. | false | false |
| 11 | 8 | The Young Victoria | $37,129 | -35.7% | 26 | - | $1,428 | $121,371 | 2 | Paradiso Entertainment | false | false |
| 12 | 15 | Antichrist | $32,659 | -7% | 13 | +1 | $2,512 | $86,432 | 2 | N/A | false | false |
| 13 | 10 | Public Enemies | $32,400 | -24% | 27 | -15 | $1,200 | $2,360,222 | 10 | Universal Pictures International (UPI) | false | false |
| 14 | 12 | The Taking of Pelham 123 | $30,776 | -20.3% | 17 | -9 | $1,810 | $1,445,868 | 9 | Sony Pictures Releasing | false | false |
| 15 | 13 | The Proposal | $29,065 | -23.8% | 17 | -10 | $1,709 | $2,842,968 | 15 | Walt Disney Pictures | false | false |
| 16 | - | Crossing Over | $27,460 | - | 17 | - | $1,615 | $38,992 | 1 | Paradiso Entertainment | true | false |
| 17 | 18 | Neuilly Yo Mama! | $24,345 | -22.2% | 15 | +5 | $1,623 | $352,438 | 6 | Les Films de l'Elysée | false | false |
| 18 | - | Farewell | $23,302 | - | 6 | - | $3,883 | $23,302 | 1 | Alternative Films | true | false |
| 19 | 14 | A Prophet | $22,462 | -39.3% | 23 | +1 | $976 | $303,757 | 5 | ABC Distribution | false | false |
| 20 | 11 | My Life in Ruins | $20,755 | -47.1% | 11 | -1 | $1,886 | $79,189 | 2 | Belga Films | false | false |
| 21 | 17 | G.I. Joe: The Rise of Cobra | $20,583 | -35.6% | 19 | -15 | $1,083 | $1,597,062 | 8 | Universal Pictures International (UPI) | false | false |
| 22 | 16 | 9 | $17,648 | -49.4% | 14 | - | $1,260 | $67,037 | 2 | A-Film Distribution | false | false |
| 23 | 19 | The Hangover | $17,354 | -42.7% | 10 | - | $1,735 | $1,985,359 | 15 | Warner Bros. | false | false |
| 24 | 20 | Het geheim van Mega Mindy | $13,845 | -20.3% | 26 | -1 | $532 | $1,589,994 | 13 | Kinepolis Film Distribution (KFD) | false | false |
| 25 | - | Away We Go | $12,325 | - | 4 | - | $3,081 | $12,325 | 1 | A-Film Distribution | true | false |
| 26 | - | Army of Crime | $12,129 | - | 7 | - | $1,732 | $15,550 | 1 | Cinéart | true | false |
| 27 | 21 | The September Issue | $11,769 | -16.3% | 3 | - | $3,923 | $29,439 | 2 | Benelux Film Distributors | false | false |
| 28 | - | Luke and Lucy: The Texas Rangers | $11,372 | - | 31 | - | $366 | $792,603 | 10 | Kinepolis Film Distribution (KFD) | false | false |
| 29 | 24 | Le coach | $10,326 | +5.4% | 17 | +1 | $607 | $58,058 | 3 | N/A | false | false |
| 30 | 22 | Regrets | $10,109 | -25.8% | 9 | -1 | $1,123 | $69,307 | 3 | Benelux Film Distributors | false | false |
| 31 | 23 | The Hedgehog | $6,785 | -41% | 11 | - | $616 | $248,982 | 8 | Cinéart | false | false |
| 32 | 25 | Partir | $5,956 | -38% | 16 | - | $372 | $299,343 | 7 | Benelux Film Distributors | false | false |
| 33 | 27 | Bandslam | $5,195 | -40.6% | 16 | -6 | $324 | $405,084 | 7 | Belga Films | false | false |
| 34 | 28 | Easy Virtue | $4,215 | -49.1% | 6 | -2 | $702 | $123,462 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 35 | - | My One and Only | $3,990 | - | 3 | - | $1,330 | $4,468 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 36 | 26 | The Time That Remains | $3,589 | -60.1% | 6 | - | $598 | $32,705 | 3 | Cinéart | false | false |
| 37 | 32 | Angels & Demons | $3,494 | -4.8% | 2 | - | $1,747 | $4,693,052 | 20 | Sony Pictures Releasing | false | false |
| 38 | 39 | The Haunting in Connecticut | $2,916 | +37.7% | 2 | -2 | $1,458 | $237,444 | 8 | Benelux Film Distributors | false | false |
| 39 | 30 | I Love You, Man | $2,670 | -53.4% | 5 | -1 | $534 | $364,114 | 9 | Universal Pictures International (UPI) | false | false |
| 40 | 31 | Passengers | $2,199 | -55.4% | 2 | -1 | $1,099 | $104,277 | 9 | Paradiso Entertainment | false | false |
| 41 | 41 | Fighting | $1,865 | -4.9% | 1 | - | $1,865 | $254,477 | 11 | Universal Pictures International (UPI) | false | false |
| 42 | 35 | Ghosts of Girlfriends Past | $1,696 | -43.6% | 1 | -2 | $1,696 | $591,291 | 13 | Kinepolis Film Distribution (KFD) | false | false |
| 43 | 33 | Drag Me to Hell | $1,249 | -65.9% | 3 | -1 | $416 | $621,264 | 14 | Belga Films | false | false |
| 44 | 44 | Princess Lillifee | $1,156 | - | 2 | - | $578 | $55,847 | 27 | Walt Disney Pictures | false | false |
| 45 | - | The Girl with the Dragon Tattoo | $855 | - | 4 | - | $213 | $584,649 | 19 | Benelux Film Distributors | false | false |
| 46 | 46 | Demain | $812 | -24.7% | 3 | -4 | $270 | $24,857 | 4 | Benelux Film Distributors | false | false |
| 47 | 38 | Brüno | $469 | -78% | 3 | -3 | $156 | $2,290,483 | 12 | Universal Pictures International (UPI) | false | false |
| 48 | - | Still Walking | $425 | - | 2 | - | $212 | $70,997 | 18 | Benelux Film Distributors | false | false |
| 49 | 48 | Transformers: Revenge of the Fallen | $410 | -58.5% | 3 | +1 | $136 | $2,966,917 | 14 | Universal Pictures International (UPI) | false | false |
| 50 | - | Silent Wedding | $232 | - | 1 | - | $232 | $7,424 | 7 | Paradiso Entertainment | false | false |
