| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Up | $510,829 | -46.6% | 75 | - | $6,811 | $1,575,077 | 2 | Walt Disney Pictures | false | false |
| 2 | - | District 9 | $230,961 | - | 50 | - | $4,619 | $230,961 | 1 | Viva International Pictures | true | false |
| 3 | - | Tarot | $224,719 | - | 70 | - | $3,210 | $224,719 | 1 | N/A | true | false |
| 4 | 2 | G.I. Joe: The Rise of Cobra | $164,495 | -63.6% | 76 | -13 | $2,164 | $3,143,738 | 4 | United International Pictures | false | false |
| 5 | 3 | And I Love You So | $124,844 | -42.9% | 65 | - | $1,920 | $939,451 | 3 | Star Cinema | false | false |
| 6 | 6 | The Time Traveler's Wife | $56,180 | -47.6% | 16 | - | $3,511 | $190,179 | 2 | Pioneer Films | false | false |
| 7 | 4 | Love on Line (LOL) | $36,995 | -82.4% | 50 | -20 | $739 | $299,334 | 2 | N/A | false | false |
| 8 | - | Shorts | $32,836 | - | 25 | - | $1,313 | $32,836 | 1 | Warner Bros. | true | false |
| 9 | 9 | Orphan | $11,282 | -60.4% | 9 | -8 | $1,253 | $291,085 | 5 | Warner Bros. | false | false |
| 10 | 5 | Aliens in the Attic | $10,918 | -90.2% | 17 | -18 | $642 | $135,541 | 2 | 20th Century Fox International | false | false |
| 11 | 7 | The Hangover | $10,822 | -71.3% | 14 | -2 | $773 | $197,184 | 3 | Warner Bros. | false | false |
| 12 | - | Bandslam | $9,988 | - | 15 | - | $665 | $9,988 | 1 | N/A | true | false |
| 13 | 8 | The Proposal | $6,972 | -80.1% | 5 | -19 | $1,394 | $1,070,087 | 5 | Walt Disney Pictures | false | false |
| 14 | 12 | Public Enemies | $6,503 | -33.2% | 5 | -8 | $1,300 | $270,485 | 6 | United International Pictures | false | false |
| 15 | 11 | Harry Potter and the Half-Blood Prince | $3,659 | -65.5% | 4 | -1 | $914 | $3,961,415 | 7 | Warner Bros. | false | false |
| 16 | 10 | Ong Bak 2 | $1,540 | -92.1% | 10 | - | $154 | $26,051 | 2 | Viva International Pictures | false | false |
