| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Up | $956,913 | - | 75 | - | $12,758 | $956,913 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | G.I. Joe: The Rise of Cobra | $452,212 | -48.4% | 89 | - | $5,081 | $2,907,895 | 3 | United International Pictures | false | false |
| 3 | 2 | And I Love You So | $218,477 | -48.5% | 65 | - | $3,361 | $749,064 | 2 | Star Cinema | false | false |
| 4 | - | Love on Line (LOL) | $209,863 | - | 70 | - | $2,998 | $209,863 | 1 | N/A | true | false |
| 5 | - | Aliens in the Attic | $111,834 | - | 35 | - | $3,195 | $111,834 | 1 | 20th Century Fox International | true | false |
| 6 | - | The Time Traveler's Wife | $107,199 | - | 16 | - | $6,699 | $107,199 | 1 | Pioneer Films | true | false |
| 7 | 4 | The Hangover | $37,756 | -68.1% | 16 | -9 | $2,359 | $180,003 | 2 | Warner Bros. | false | false |
| 8 | 3 | The Proposal | $35,090 | -73.8% | 24 | -26 | $1,462 | $1,056,438 | 4 | Walt Disney Pictures | false | false |
| 9 | 5 | Orphan | $28,504 | -32.7% | 17 | -11 | $1,676 | $274,203 | 4 | Warner Bros. | false | false |
| 10 | - | Ong Bak 2 | $19,601 | - | 10 | - | $1,960 | $19,601 | 1 | Viva International Pictures | true | false |
| 11 | 6 | Harry Potter and the Half-Blood Prince | $10,596 | -72% | 5 | -20 | $2,119 | $3,956,467 | 6 | Warner Bros. | false | false |
| 12 | 9 | Public Enemies | $9,732 | -38.6% | 13 | -4 | $748 | $261,659 | 5 | United International Pictures | false | false |
| 13 | 7 | Book of Blood | $6,388 | -81% | 10 | -4 | $638 | $50,104 | 2 | Pioneer Films | false | false |
| 14 | 8 | Oh, My Girl!: A Laugh Story... | $4,702 | -84.1% | 36 | -24 | $130 | $463,608 | 4 | N/A | false | false |
| 15 | 10 | Transformers: Revenge of the Fallen | $1,377 | -76.7% | 1 | -2 | $1,377 | $7,384,179 | 9 | United International Pictures | false | false |
