| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | G.I. Joe: The Rise of Cobra | $480,577 | - | 50 | - | $9,611 | $480,577 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Harry Potter and the Half-Blood Prince | $453,852 | -50.6% | 170 | +27 | $2,669 | $7,369,007 | 4 | Warner Bros. | false | false |
| 3 | 2 | Ice Age: Dawn of the Dinosaurs | $313,833 | -48.1% | 129 | -31 | $2,432 | $7,486,666 | 6 | 20th Century Fox International | false | false |
| 4 | 3 | G-Force | $276,002 | -54.3% | 76 | -3 | $3,631 | $989,681 | 2 | Walt Disney Pictures | false | false |
| 5 | 5 | Public Enemies | $204,258 | -48.8% | 53 | +3 | $3,853 | $1,509,564 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | The Taking of Pelham 123 | $196,036 | -52.9% | 45 | - | $4,356 | $692,140 | 2 | Sony Pictures Releasing | false | false |
| 7 | 9 | The Proposal | $88,457 | -18.6% | 40 | -1 | $2,211 | $2,391,359 | 8 | Walt Disney Pictures | false | false |
| 8 | 6 | Brüno | $85,088 | -46.8% | 39 | -1 | $2,181 | $2,077,230 | 5 | Universal Pictures International (UPI) | false | false |
| 9 | 8 | Luke and Lucy: The Texas Rangers | $57,269 | -54.4% | 52 | - | $1,101 | $430,526 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 10 | 7 | Het geheim van Mega Mindy | $54,181 | -57.8% | 33 | - | $1,641 | $1,236,674 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 11 | 12 | The Hangover | $52,395 | -32.6% | 32 | +8 | $1,637 | $1,694,641 | 8 | Warner Bros. | false | false |
| 12 | 10 | I Love You, Man | $48,932 | -46.8% | 20 | - | $2,446 | $234,553 | 2 | Universal Pictures International (UPI) | false | false |
| 13 | - | The Hedgehog | $47,408 | - | 12 | - | $3,950 | $48,841 | 1 | Cinéart | true | false |
| 14 | - | The Haunting in Connecticut | $46,193 | - | 12 | - | $3,849 | $59,132 | 1 | Benelux Film Distributors | true | false |
| 15 | 11 | Transformers: Revenge of the Fallen | $40,456 | -48% | 40 | -12 | $1,011 | $2,901,645 | 7 | Universal Pictures International (UPI) | false | false |
| 16 | 13 | Hannah Montana: The Movie | $24,575 | -42.7% | 32 | -2 | $767 | $543,991 | 5 | Walt Disney Pictures | false | false |
| 17 | - | The Brothers Bloom | $16,870 | - | 8 | - | $2,108 | $19,244 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 18 | 14 | Ghosts of Girlfriends Past | $14,454 | -47.7% | 11 | - | $1,314 | $545,213 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 19 | 15 | Angels & Demons | $14,263 | -46.5% | 7 | -2 | $2,037 | $4,617,593 | 13 | Sony Pictures Releasing | false | false |
| 20 | 17 | Drag Me to Hell | $12,046 | -39.3% | 12 | -2 | $1,003 | $574,750 | 7 | Belga Films | false | false |
| 21 | 24 | Passengers | $11,805 | +70.9% | 6 | - | $1,967 | $49,076 | 2 | Paradiso Entertainment | false | false |
| 22 | 18 | Blame It on Mum | $10,231 | -42.7% | 11 | - | $930 | $91,423 | 3 | Cinéart | false | false |
| 23 | 16 | Fighting | $9,913 | -56.3% | 7 | -5 | $1,416 | $222,251 | 4 | Universal Pictures International (UPI) | false | false |
| 24 | 20 | Broken Embraces | $9,283 | -20.7% | 15 | - | $618 | $659,288 | 12 | Alternative Films | false | false |
| 25 | - | Princess Lillifee | $8,722 | - | 14 | - | $623 | $28,926 | 20 | Walt Disney Pictures | false | false |
| 26 | 31 | Coraline | $8,548 | +341.5% | 16 | +8 | $534 | $463,837 | 9 | Universal Pictures International (UPI) | false | false |
| 27 | 29 | Alternate Weeks (and Half the Vacation) | $5,691 | +68.2% | 6 | -2 | $948 | $44,614 | 2 | Les Films de l'Elysée | false | false |
| 28 | 21 | State of Play | $5,585 | -32.8% | 8 | +2 | $698 | $547,221 | 8 | Universal Pictures International (UPI) | false | false |
| 29 | 23 | Kabuli Kid | $4,903 | -30.5% | 4 | - | $1,225 | $14,577 | 2 | N/A | false | false |
| 30 | - | Mid-August Lunch | $4,491 | - | 6 | - | $748 | $118,616 | 9 | ABC Distribution | false | false |
| 31 | 19 | Towelhead | $4,465 | -69.9% | 9 | -2 | $496 | $24,983 | 2 | Benelux Film Distributors | false | false |
| 32 | 22 | Looking for Eric | $4,446 | -41.9% | 15 | - | $296 | $280,023 | 9 | Cinéart | false | false |
| 33 | 25 | Disgrace | $3,177 | -46.5% | 5 | - | $635 | $22,246 | 3 | A-Film Distribution | false | false |
| 34 | 32 | The Girl with the Dragon Tattoo | $2,944 | +65.4% | 5 | +1 | $588 | $577,230 | 12 | Benelux Film Distributors | false | false |
| 35 | - | The Window | $2,289 | - | 4 | - | $572 | $3,079 | 1 | ABC Distribution | true | false |
| 36 | 26 | A Town Called Panic | $2,202 | -47.7% | 11 | - | $200 | $139,726 | 8 | Cinéart | false | false |
| 37 | 27 | Night at the Museum: Battle of the Smithsonian | $1,444 | -65.3% | 3 | -6 | $481 | $2,449,746 | 12 | 20th Century Fox International | false | false |
| 38 | 30 | Mammoth | $1,002 | -52.7% | 4 | -2 | $250 | $24,207 | 5 | A-Film Distribution | false | false |
| 39 | 28 | The French Kissers | $856 | -77.2% | 6 | -2 | $142 | $282,220 | 7 | Alternative Films | false | false |
| 40 | - | Soi Cowboy | $657 | - | 2 | - | $328 | $657 | 1 | N/A | true | false |
| 41 | 37 | Two-Legged Horse | $594 | -53.3% | 2 | - | $297 | $5,157 | 2 | N/A | false | false |
| 42 | 41 | The Reader | $316 | -46.3% | 1 | -1 | $316 | $912,152 | 23 | Benelux Film Distributors | false | false |
| 43 | - | Masangeles 2009 Re-release | $301 | - | 2 | - | $150 | $755 | 1 | N/A | true | false |
