| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Proposal | $444,756 | - | 50 | - | $8,895 | $476,946 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Harry Potter and the Half-Blood Prince | $295,929 | -63.6% | 105 | - | $2,818 | $3,700,701 | 3 | Warner Bros. | false | false |
| 3 | - | Oh, My Girl!: A Laugh Story... | $216,396 | - | 72 | - | $3,005 | $216,396 | 1 | N/A | true | false |
| 4 | - | Orphan | $89,443 | - | 30 | - | $2,981 | $89,443 | 1 | Warner Bros. | true | false |
| 5 | 2 | Ice Age: Dawn of the Dinosaurs | $86,037 | -55% | 40 | -35 | $2,150 | $2,343,137 | 5 | 20th Century Fox International | false | false |
| 6 | 3 | Public Enemies | $51,129 | -58.4% | 16 | - | $3,195 | $201,099 | 2 | United International Pictures | false | false |
| 7 | - | Nothing But the Truth | $25,801 | - | 16 | - | $1,612 | $25,801 | 1 | Pioneer Films | true | false |
| 8 | 4 | Transformers: Revenge of the Fallen | $25,799 | -71.4% | 23 | -44 | $1,121 | $7,356,833 | 6 | United International Pictures | false | false |
| 9 | 5 | It's Alive | $20,766 | -64.3% | 18 | - | $1,153 | $90,886 | 2 | Viva International Pictures | false | false |
| 10 | 9 | Hannah Montana: The Movie | $8,383 | -51.6% | 9 | -11 | $931 | $232,126 | 4 | Walt Disney Pictures | false | false |
| 11 | 7 | My Sister's Keeper | $7,449 | -71.2% | 15 | - | $496 | $41,157 | 2 | Pioneer Films | false | false |
| 12 | - | The Taking of Pelham 123 | $2,180 | - | 3 | - | $726 | $519,149 | 1 | Sony Pictures Releasing | true | false |
| 13 | 12 | Adventureland | $1,404 | -76.8% | 1 | - | $1,404 | $9,095 | 2 | Walt Disney Pictures | false | false |
