| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Half-Blood Prince | $1,134,285 | - | 113 | - | $10,037 | $1,134,285 | 1 | Warner Bros. | true | false |
| 2 | 1 | Transformers: Revenge of the Fallen | $263,536 | -65.8% | 82 | - | $3,213 | $7,495,502 | 4 | United International Pictures | false | false |
| 3 | - | Skrip 7707 | $260,764 | - | 45 | - | $5,794 | $260,764 | 1 | N/A | true | false |
| 4 | 2 | Ice Age: Dawn of the Dinosaurs | $245,295 | -54.4% | 91 | - | $2,695 | $2,014,697 | 3 | 20th Century Fox International | false | false |
| 5 | 3 | Public Enemies | $72,836 | -46.5% | 27 | - | $2,697 | $259,735 | 2 | United International Pictures | false | false |
| 6 | 4 | Obsessed | $56,056 | -43.4% | 38 | - | $1,475 | $188,505 | 2 | Sony Pictures Releasing | false | false |
| 7 | - | Vedikondu Murugesu | $14,634 | - | 7 | - | $2,090 | $14,634 | 1 | N/A | true | false |
| 8 | - | Comatose | $9,104 | - | 10 | - | $910 | $41,140 | 2 | N/A | false | false |
| 9 | 5 | Drag Me to Hell | $7,962 | -76.7% | 9 | -20 | $884 | $829,486 | 7 | Golden Screen Cinemas | false | false |
| 10 | 7 | Kambakkht Ishq | $5,672 | -55.5% | 10 | - | $567 | $55,606 | 3 | N/A | false | false |
| 11 | 6 | The Last House on the Left | $3,936 | -77.1% | 9 | -3 | $437 | $201,832 | 5 | United International Pictures | false | false |
| 12 | - | Achchamundu! Achchamundu! | $3,209 | - | 3 | - | $1,069 | $3,209 | 1 | Five Star | true | false |
| 13 | 11 | Night at the Museum: Battle of the Smithsonian | $2,235 | -64.2% | 5 | -7 | $447 | $2,819,219 | 9 | 20th Century Fox International | false | false |
| 14 | - | Naadodigal | $1,910 | - | 5 | - | $382 | $38,695 | 4 | Five Star | false | false |
| 15 | 8 | Terminator Salvation | $1,823 | -82.3% | 10 | -16 | $182 | $3,882,916 | 8 | Sony Pictures Releasing | false | false |
| 16 | 13 | Departures | $1,552 | -54.4% | 3 | - | $517 | $23,576 | 5 | Golden Screen Cinemas | false | false |
| 17 | 10 | Blood: The Last Vampire | $1,465 | -77.6% | 7 | -10 | $209 | $553,601 | 6 | Sony Pictures Releasing | false | false |
| 18 | 12 | Hannah Montana: The Movie | $1,311 | -74.3% | 9 | -8 | $145 | $275,736 | 7 | Walt Disney Pictures | false | false |
| 19 | - | Mutthirai | $976 | - | 3 | - | $325 | $14,404 | 5 | Five Star | false | false |
| 20 | - | Indihira Vizha | $781 | - | 2 | - | $390 | $4,765 | 2 | Five Star | false | false |
| 21 | 9 | 17 Again | $668 | -90.9% | 3 | -13 | $222 | $448,329 | 6 | Golden Screen Cinemas | false | false |
| 22 | 18 | Masss | $551 | -40.3% | 6 | - | $91 | $32,350 | 6 | Five Star | false | false |
| 23 | - | Fighting | $323 | - | 4 | - | $80 | $95,143 | - | United International Pictures | - | false |
| 24 | 16 | Mayandi Kudumbathar | $192 | -83.1% | 1 | -1 | $192 | $19,390 | 7 | Five Star | false | false |
| 25 | 15 | State of Play | $138 | -93.7% | 8 | - | $17 | $101,954 | 6 | United International Pictures | false | false |
| 26 | 21 | Angels & Demons | $70 | -87.9% | 1 | -1 | $70 | $1,363,515 | 10 | Sony Pictures Releasing | false | false |
| 27 | 22 | Dance Subaru | $68 | -84.5% | 1 | -2 | $68 | $24,007 | 5 | N/A | false | false |
| 28 | 17 | Forever Enthralled | $66 | -93.9% | 1 | -4 | $66 | $4,857 | 3 | N/A | false | false |
