| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Hangover | $545,572 | - | 69 | - | $7,906 | $665,629 | 1 | Warner Bros. | true | false |
| 2 | 1 | Ice Age: Dawn of the Dinosaurs | $254,990 | -48% | 122 | -22 | $2,090 | $2,720,373 | 3 | 20th Century Fox International | false | false |
| 3 | - | Last Chance Harvey | $144,516 | - | 12 | - | $12,043 | $144,516 | 1 | Hollywood Entertainment | true | false |
| 4 | 2 | Public Enemies | $115,350 | -56.8% | 43 | -22 | $2,682 | $1,276,355 | 3 | United International Pictures | false | false |
| 5 | 3 | Brüno | $80,766 | -52% | 30 | - | $2,692 | $355,396 | 2 | Sony Pictures Releasing | false | false |
| 6 | - | Transformers | $39,823 | - | 28 | - | $1,422 | $1,490,176 | 106 | United International Pictures | false | false |
| 7 | 5 | The Proposal | $27,107 | -65.6% | 25 | -19 | $1,084 | $1,079,232 | 4 | Walt Disney Pictures | false | false |
| 8 | - | Blood: The Last Vampire | $26,066 | - | 14 | - | $1,861 | $26,066 | 1 | Odeon | true | false |
| 9 | 7 | The Code | $20,092 | -62.9% | 13 | -6 | $1,545 | $108,189 | 2 | Odeon | false | false |
| 10 | 12 | Angels & Demons | $916 | -36.3% | 3 | - | $305 | $4,737,719 | 10 | Sony Pictures Releasing | false | false |
| 11 | 11 | Terminator Salvation | $656 | -92.5% | 3 | -5 | $218 | $1,600,203 | 7 | Sony Pictures Releasing | false | false |
